Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms P Baker, PJ Hill, BD Snarr, N Alnabelseya, MJ Pestrak, MJ Lee, ... Science advances 2 (5), e1501632, 2016 | 322 | 2016 |
PelA deacetylase activity is required for Pel polysaccharide synthesis in Pseudomonas aeruginosa KM Colvin, N Alnabelseya, P Baker, JC Whitney, PL Howell, MR Parsek Journal of bacteriology 195 (10), 2329-2339, 2013 | 158 | 2013 |
Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus*♦ NC Bamford, BD Snarr, FN Gravelat, DJ Little, MJ Lee, CA Zacharias, ... Journal of Biological Chemistry 290 (46), 27438-27450, 2015 | 102 | 2015 |
Characterization of the Pseudomonas aeruginosa glycoside hydrolase PslG reveals that its levels are critical for Psl polysaccharide biosynthesis and biofilm formation P Baker, GB Whitfield, PJ Hill, DJ Little, MJ Pestrak, H Robinson, ... Journal of Biological Chemistry 290 (47), 28374-28387, 2015 | 98 | 2015 |
Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity BD Snarr, P Baker, NC Bamford, Y Sato, H Liu, M Lehoux, FN Gravelat, ... Proceedings of the National Academy of Sciences 114 (27), 7124-7129, 2017 | 97 | 2017 |
Treatment with the Pseudomonas aeruginosa glycoside hydrolase PslG combats wound infection by improving antibiotic efficacy and host innate immune activity MJ Pestrak, P Baker, S Dellos-Nolan, PJ Hill, D Passos da Silva, H Silver, ... Antimicrobial agents and chemotherapy 63 (6), 10.1128/aac. 00234-19, 2019 | 92 | 2019 |
P. aeruginosa SGNH Hydrolase-Like Proteins AlgJ and AlgX Have Similar Topology but Separate and Distinct Roles in Alginate Acetylation P Baker, T Ricer, PJ Moynihan, EN Kitova, MTC Walvoort, DJ Little, ... PLoS pathogens 10 (8), e1004334, 2014 | 79 | 2014 |
Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation LM Riley, JT Weadge, P Baker, H Robinson, JDC Codée, PA Tipton, ... Journal of Biological Chemistry 288 (31), 22299-22314, 2013 | 78 | 2013 |
PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β (1, 6)-N-acetylglucosamine and can disrupt bacterial biofilms DJ Little, R Pfoh, F Le Mauff, NC Bamford, C Notte, P Baker, M Guragain, ... PLoS pathogens 14 (4), e1006998, 2018 | 74 | 2018 |
Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases F Le Mauff, NC Bamford, N Alnabelseya, Y Zhang, P Baker, H Robinson, ... Journal of Biological Chemistry 294 (28), 10760-10772, 2019 | 64 | 2019 |
Non-eluting, surface-bound enzymes disrupt surface attachment of bacteria by continuous biofilm polysaccharide degradation D Asker, TS Awad, P Baker, PL Howell, BD Hatton Biomaterials 167, 168-176, 2018 | 55 | 2018 |
Comparison of two metal-dependent pyruvate aldolases related by convergent evolution: substrate specificity, kinetic mechanism, and substrate channeling W Wang, P Baker, SYK Seah Biochemistry 49 (17), 3774-3782, 2010 | 55 | 2010 |
Characterization of an aldolase− dehydrogenase complex that exhibits substrate channeling in the polychlorinated biphenyls degradation pathway P Baker, D Pan, J Carere, A Rossi, W Wang, SYK Seah Biochemistry 48 (27), 6551-6558, 2009 | 48 | 2009 |
Rational design of stereoselectivity in the class II pyruvate aldolase BphI P Baker, SYK Seah Journal of the American Chemical Society 134 (1), 507-513, 2012 | 45 | 2012 |
An epigenetic mechanism regulates germ cell-specific expression of the porcine Deleted in Azoospermia-Like (DAZL) gene K Linher, Q Cheung, P Baker, G Bedecarrats, K Shiota, J Li Differentiation 77 (4), 335-349, 2009 | 44 | 2009 |
Probing the molecular basis of substrate specificity, stereospecificity, and catalysis in the class II pyruvate aldolase, BphI P Baker, J Carere, SYK Seah Biochemistry 50 (17), 3559-3569, 2011 | 34 | 2011 |
Protein–protein interactions and substrate channeling in Orthologous and chimeric aldolase–dehydrogenase complexes P Baker, C Hillis, J Carere, SYK Seah Biochemistry 51 (9), 1942-1952, 2012 | 33 | 2012 |
Investigating the molecular determinants for substrate channeling in BphI–BphJ, an aldolase–dehydrogenase complex from the polychlorinated biphenyls degradation pathway J Carere, P Baker, SYK Seah Biochemistry 50 (39), 8407-8416, 2011 | 28 | 2011 |
Substrate specificity, substrate channeling, and allostery in BphJ: an acylating aldehyde dehydrogenase associated with the pyruvate aldolase BphI P Baker, J Carere, SYK Seah Biochemistry 51 (22), 4558-4567, 2012 | 17 | 2012 |
Distinct types of multicellular aggregates in Pseudomonas aeruginosa liquid cultures G Melaugh, VA Martinez, P Baker, PJ Hill, PL Howell, DJ Wozniak, ... npj Biofilms and Microbiomes 9 (1), 52, 2023 | 15 | 2023 |