Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19 ATTACC, ACTIV-4a, and REMAP-CAP Investigators New England Journal of Medicine 385 (9), 790-802, 2021 | 1131 | 2021 |
Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: the REMAP-CAP COVID-19 corticosteroid domain randomized clinical trial DC Angus, L Derde, F Al-Beidh, D Annane, Y Arabi, A Beane, ... Jama 324 (13), 1317-1329, 2020 | 878 | 2020 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 807 | 2021 |
Restrictive or liberal red-cell transfusion for cardiac surgery CD Mazer, RP Whitlock, DA Fergusson, J Hall, E Belley-Cote, K Connolly, ... New England Journal of Medicine 377 (22), 2133-2144, 2017 | 737 | 2017 |
Interleukin-6 receptor antagonists in critically ill patients with Covid-19 Remap-Cap Investigators New England Journal of Medicine 384 (16), 1491-1502, 2021 | 659 | 2021 |
Whole-genome sequencing reveals host factors underlying critical COVID-19 A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ... Nature 607 (7917), 97-103, 2022 | 286 | 2022 |
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial P Bégin, J Callum, E Jamula, R Cook, NM Heddle, A Tinmouth, MP Zeller, ... Nature medicine 27 (11), 2012-2024, 2021 | 270 | 2021 |
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity S Zhou, G Butler-Laporte, T Nakanishi, DR Morrison, J Afilalo, M Afilalo, ... Nature medicine 27 (4), 659-667, 2021 | 251 | 2021 |
Six-month outcomes after restrictive or liberal transfusion for cardiac surgery CD Mazer, RP Whitlock, DA Fergusson, E Belley-Cote, K Connolly, ... New England Journal of Medicine 379 (13), 1224-1233, 2018 | 240 | 2018 |
Intravenous vitamin C in adults with sepsis in the intensive care unit F Lamontagne, MH Masse, J Menard, S Sprague, R Pinto, DK Heyland, ... New England Journal of Medicine 386 (25), 2387-2398, 2022 | 228 | 2022 |
Alterations in portal vein flow and intrarenal venous flow are associated with acute kidney injury after cardiac surgery: a prospective observational cohort study W Beaubien‐Souligny, A Benkreira, P Robillard, N Bouabdallaoui, ... Journal of the American Heart Association 7 (19), e009961, 2018 | 227 | 2018 |
Effect of convalescent plasma on organ support–free days in critically ill patients with COVID-19: a randomized clinical trial H Abdelhady, M Abdelrazik, Z Abdi, D Abdo, A Abdulle, L Abel, ... Jama 326 (17), 1690-1702, 2021 | 204 | 2021 |
Levofloxacin for BK virus prophylaxis following kidney transplantation: a randomized clinical trial GA Knoll, A Humar, D Fergusson, O Johnston, AA House, SJ Kim, ... Jama 312 (20), 2106-2114, 2014 | 146 | 2014 |
Association of blood donor age and sex with recipient survival after red blood cell transfusion M Chassé, A Tinmouth, SW English, JP Acker, K Wilson, G Knoll, ... JAMA internal medicine 176 (9), 1307-1314, 2016 | 124 | 2016 |
Effect of probiotics on incident ventilator-associated pneumonia in critically ill patients: a randomized clinical trial J Johnstone, M Meade, F Lauzier, J Marshall, E Duan, J Dionne, YM Arabi, ... Jama 326 (11), 1024-1033, 2021 | 122 | 2021 |
Long-term (180-day) outcomes in critically ill patients with COVID-19 in the REMAP-CAP randomized clinical trial S Florescu, D Stanciu, M Zaharia, A Kosa, D Codreanu, A Kidwai, ... Jama 329 (1), 39-51, 2023 | 116 | 2023 |
Ramipril versus placebo in kidney transplant patients with proteinuria: a multicentre, double-blind, randomised controlled trial GA Knoll, D Fergusson, M Chassé, P Hebert, G Wells, LA Tibbles, ... The lancet Diabetes & endocrinology 4 (4), 318-326, 2016 | 106 | 2016 |
Resumption of cardiac activity after withdrawal of life-sustaining measures S Dhanani, L Hornby, A van Beinum, NB Scales, M Hogue, A Baker, ... New England Journal of Medicine 384 (4), 345-352, 2021 | 103 | 2021 |
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial YM Arabi, AC Gordon, LPG Derde, AD Nichol, S Murthy, FA Beidh, ... Intensive care medicine 47, 867-886, 2021 | 96 | 2021 |
Effect of blood donor characteristics on transfusion outcomes: a systematic review and meta-analysis M Chassé, L McIntyre, SW English, A Tinmouth, G Knoll, D Wolfe, ... Transfusion medicine reviews 30 (2), 69-80, 2016 | 92 | 2016 |