| Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs KP Ponder, JR Melniczek, L Xu, MA Weil, TM O'Malley, PA O'Donnell, ... Proceedings of the National Academy of Sciences 99 (20), 13102-13107, 2002 | 212 | 2002 |
| Gene therapy for lysosomal storage diseases: the lessons and promise of animal models NM Ellinwood, CH Vite, ME Haskins The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 160 | 2004 |
| Safe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes NM Ellinwood, J Ausseil, N Desmaris, S Bigou, S Liu, JK Jens, EM Snella, ... Molecular therapy 19 (2), 251-259, 2011 | 157 | 2011 |
| Derivation of adult canine intestinal organoids for translational research in gastroenterology L Chandra, DC Borcherding, D Kingsbury, T Atherly, YM Ambrosini, ... BMC biology 17, 1-21, 2019 | 116 | 2019 |
| Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor BL Brim, R Haskell, R Awedikian, NM Ellinwood, L Jin, A Kumar, ... Behavioural brain research 238, 211-226, 2013 | 88 | 2013 |
| MC1R Studies in Dogs With Melanistic Mask or Brindle Patterns SM Schmutz, TG Berryere, NM Ellinwood, JA Kerns, GS Barsh Journal of Heredity 94 (1), 69-73, 2003 | 88 | 2003 |
| Replacing the enzyme α-l-iduronidase at birth ameliorates symptoms in the brain and periphery of dogs with mucopolysaccharidosis type I AD Dierenfeld, MF McEntee, CA Vogler, CH Vite, AH Chen, M Passage, ... Science translational medicine 2 (60), 60ra89-60ra89, 2010 | 86 | 2010 |
| A model of mucopolysaccharidosis IIIB (Sanfilippo syndrome type IIIB): N‐acetyl‐α‐D‐glucosaminidase deficiency in Schipperke dogs NM Ellinwood, P Wang, T Skeen, NJH Sharp, M Cesta, S Decker, ... Journal of inherited metabolic disease 26 (5), 489-504, 2003 | 83 | 2003 |
| Evaluation of pathological manifestations of disease in mucopolysaccharidosis VII mice after neonatal hepatic gene therapy L Xu, RL Mango, MS Sands, ME Haskins, NM Ellinwood, KP Ponder Molecular Therapy 6 (6), 745-758, 2002 | 73 | 2002 |
| Transduction of hepatocytes after neonatal delivery of a Moloney murine leukemia virus based retroviral vector results in long-term expression of β-glucuronidase in … L Xu, ME Haskins, JR Melniczek, C Gao, MA Weil, TM O'malley, ... Molecular Therapy 5 (2), 141-153, 2002 | 71 | 2002 |
| Gene therapy ameliorates cardiovascular disease in dogs with mucopolysaccharidosis VII MM Sleeper, B Fornasari, NM Ellinwood, MA Weil, J Melniczek, ... Circulation 110 (7), 815-820, 2004 | 64 | 2004 |
| Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I PI Dickson, S Hanson, MF McEntee, CH Vite, CA Vogler, A Mlikotic, ... Molecular genetics and metabolism 101 (2-3), 115-122, 2010 | 62 | 2010 |
| Cloning and characterization of cDNAs for a bovine (Bos taurus) Mx protein NM ELLINWOOD, JM McCUE, PW GORDY, RA BOWEN Journal of interferon & cytokine research 18 (9), 745-755, 1998 | 60 | 1998 |
| Mucopolysaccharidosis I cats mount a cytotoxic T lymphocyte response after neonatal gene therapy that can be blocked with CTLA4-Ig KP Ponder, B Wang, P Wang, X Ma, R Herati, B Wang, K Cullen, ... Molecular Therapy 14 (1), 5-13, 2006 | 53 | 2006 |
| Normal canine brain maturation at magnetic resonance imaging B Gross, D GARCIA‐TAPIA, E Riedesel, NM Ellinwood, JK Jens Veterinary Radiology & Ultrasound 51 (4), 361-373, 2010 | 49 | 2010 |
| Animal models for mucopolysaccharidoses and their clinical relevance M Haskins, M Casal, NM Ellinwood, J Melniczek, H Mazrier, U Giger Acta Paediatrica 91, 88-97, 2002 | 49 | 2002 |
| Not all SCID pigs are created equally: two independent mutations in the Artemis gene cause SCID in pigs EH Waide, J Dekkers, JW Ross, RRR Rowland, CR Wyatt, CL Ewen, ... The Journal of Immunology 195 (7), 3171-3179, 2015 | 47 | 2015 |
| Biodistribution and pharmacodynamics of recombinant human alpha-L-iduronidase (rhIDU) in mucopolysaccharidosis type I-affected cats following multiple intrathecal administrations CH Vite, P Wang, RT Patel, RM Walton, SU Walkley, RS Sellers, ... Molecular genetics and metabolism 103 (3), 268-274, 2011 | 46 | 2011 |
| Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs B Wang, TM O’Malley, L Xu, C Vite, P Wang, PA O’Donnell, NM Ellinwood, ... Molecular genetics and metabolism 87 (1), 8-21, 2006 | 43 | 2006 |
| Association of MITF with white spotting in Beagle crosses and Newfoundland dogs. MF Rothschild, PS Van Cleave, KL Glenn, LP Carlstrom, NM Ellinwood Animal genetics 37 (6), 2006 | 40 | 2006 |
Markus H. KuehnProfessor, The University of IowaVerified email at uiowa.edu
