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Tharaka Wijerathne
Tharaka Wijerathne
Postdoctoral Research Associate
Verified email at westernu.edu - Homepage
Title
Cited by
Cited by
Year
Psoralea corylifolia extract induces vasodilation in rat arteries through both endothelium-dependent and -independent mechanisms involving inhibition of TRPC3 …
A Kassahun Gebremeskel, TD Wijerathne, JH Kim, MJ Kim, CS Seo, ...
Pharmaceutical biology 55 (1), 2136-2144, 2017
262017
Yoda1’s energetic footprint on Piezo1 channels and its modulation by voltage and temperature
TD Wijerathne, AD Ozkan, JJ Lacroix
Proceedings of the National Academy of Sciences 119 (29), e2202269119, 2022
222022
Applications of seafood by-products in the food industry and human nutrition
JK Vidanarachchi, CS Ranadheera, TD Wijerathne, RMC Udayangani, ...
Seafood Processing By-products: Trends and Applications, 463-528, 2014
212014
Distinct gating mechanism of SOC channel involving STIM–Orai coupling and an intramolecular interaction of Orai in Caenorhabditis elegans
KM Kim, T Wijerathne, JH Hur, UJ Kang, IH Kim, YC Kweon, AR Lee, ...
Proceedings of the National Academy of Sciences 115 (20), E4623-E4632, 2018
172018
Onion peel extract and its constituent, quercetin inhibits human Slo3 in a pH and calcium dependent manner
TD Wijerathne, JH Kim, MJ Kim, CY Kim, MR Chae, SW Lee, KP Lee
The Korean Journal of Physiology & Pharmacology: Official Journal of the …, 2019
112019
Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BKCa activator LDD175
KPL Tharaka Darshana Wijerathne, Jihyun Kim, Dongki Yang
The Korean Journal of Physiology & Pharmacology 21 (2), 241-249, 2017
9*2017
An inter-channel cooperative mechanism mediates PIEZO1’s exquisite mechanosensitivity
T Wijerathne, AD Ozkan, W Jiang, Y Luo, JJ Lacroix
bioRxiv, 2021.04. 16.440217, 2021
42021
Structural and thermodynamic framework for PIEZO1 modulation by small molecules
W Jiang, TD Wijerathne, H Zhang, YC Lin, S Jo, W Im, JJ Lacroix, YL Luo
Proceedings of the National Academy of Sciences 120 (50), e2310933120, 2023
32023
Force-induced motions of the PIEZO1 blade probed with fluorimetry
AD Ozkan, TD Wijerathne, T Gettas, JJ Lacroix
Cell reports 42 (8), 2023
22023
Microscopic mechanism of PIEZO1 activation by pressure-induced membrane stretch
TD Wijerathne, AD Ozkan, JJ Lacroix
Journal of General Physiology 155 (5), e202213260, 2023
22023
In vitro assessment of Prunus japonica seed extract on human spermatozoa hypermotility and intracellular alkalization
JH Kim, MR Chae, TD Wijerathne, AD Cooray, CY Kim, SW Lee, KP Lee
Andrologia 54 (8), e14471, 2022
22022
Rearrangements of Piezo1 blade domains correlate with pore opening
AD Ozkan, TD Wijerathne, T Gettas, JJ Lacroix
biorxiv, 2022
22022
Hexane fraction of Prunus japonica thunb. Seed extract enhances boar sperm motility via CatSper ion channel
A Cooray, MR Chae, TD Wijerathne, DG Kim, J Kim, CY Kim, SW Lee, ...
Heliyon 9 (2), 2023
12023
Hydrophobic interactions within the C terminus pole helices tunnel regulate calcium-dependent inactivation of TRPC3 in a calmodulin-dependent manner
T Wijerathne, WY Lin, A Cooray, S Muallem, KP Lee
Cell Calcium 109, 102684, 2023
12023
PIEZO1 discriminates mechanical stimuli
AD Ozkan, TD Wijerathne, T Gettas, JJ Lacroix
bioRxiv, 2022.06. 23.497409, 2022
12022
Voltage-clamp fluorometry to record flow-activated PIEZO1 currents and fluorometric signals
T Wijerathne, J Lacroix
STAR protocols 5 (1), 102789, 2024
2024
Kinetics and permeation properties of mammalian Piezo channels
TD Wijerathne, JJ Lacroix
Biophysical Journal 123 (3), 331a-332a, 2024
2024
Rationale design of novel PIEZO1 modulators
W Jiang, TD Wijerathne, H Zhang, YC Lin, W Im, JJ Lacroix, YL Luo
Biophysical Journal 122 (3), 396a, 2023
2023
Energetic destabilization of shut states underpins the membrane stretch dependent activation of Piezo1
TD Wijerathne, AD Ozkan, JJ Lacroix
Biophysical Journal 122 (3), 522a, 2023
2023
Long-range retrograde mechanical coupling in the PIEZO1 channel
AD Ozkan, TD Wijerathne, JJ Lacroix
Biophysical Journal 121 (3), 492a-493a, 2022
2022
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Articles 1–20