ANS binding reveals common features of cytotoxic amyloid species B Bolognesi, JR Kumita, TP Barros, EK Esbjorner, LM Luheshi, ... ACS chemical biology 5 (8), 735-740, 2010 | 421 | 2010 |
The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide P Narayan, A Orte, RW Clarke, B Bolognesi, S Hook, KA Ganzinger, ... Nature structural & molecular biology 19 (1), 79-83, 2012 | 309 | 2012 |
A concentration-dependent liquid phase separation can cause toxicity upon increased protein expression B Bolognesi, NL Gotor, R Dhar, D Cirillo, M Baldrighi, GG Tartaglia, ... Cell reports 16 (1), 222-231, 2016 | 271 | 2016 |
The mutational landscape of a prion-like domain B Bolognesi, AJ Faure, M Seuma, JM Schmiedel, GG Tartaglia, B Lehner Nature communications 10 (1), 4162, 2019 | 141 | 2019 |
The controlling roles of Trp60 and Trp95 in β2-microglobulin function, folding and amyloid aggregation properties G Esposito, S Ricagno, A Corazza, E Rennella, D Gümral, MC Mimmi, ... Journal of molecular biology 378 (4), 887-897, 2008 | 106 | 2008 |
Detergent-like interaction of Congo red with the amyloid β peptide C Lendel, B Bolognesi, A Wahlström, CM Dobson, A Graslund Biochemistry 49 (7), 1358-1360, 2010 | 89 | 2010 |
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein R Porcari, C Proukakis, CA Waudby, B Bolognesi, PP Mangione, ... Journal of Biological Chemistry 290 (4), 2395-2404, 2015 | 85 | 2015 |
Neurodegenerative diseases: quantitative predictions of protein–RNA interactions D Cirillo, F Agostini, P Klus, D Marchese, S Rodriguez, B Bolognesi, ... Rna 19 (2), 129-140, 2013 | 82 | 2013 |
Disulfide bonds reduce the toxicity of the amyloid fibrils formed by an extracellular protein MF Mossuto, B Bolognesi, B Guixer, A Dhulesia, F Agostini, JR Kumita, ... Angewandte Chemie 123 (31), 7186-7189, 2011 | 70 | 2011 |
Reaching the limit B Bolognesi, B Lehner Elife 7, e39804, 2018 | 68 | 2018 |
An integrative study of protein-RNA condensates identifies scaffolding RNAs and reveals players in fragile X-associated tremor/ataxia syndrome F Cid-Samper, M Gelabert-Baldrich, B Lang, N Lorenzo-Gotor, RD Ponti, ... Cell reports 25 (12), 3422-3434. e7, 2018 | 67 | 2018 |
The cleverSuite approach for protein characterization: predictions of structural properties, solubility, chaperone requirements and RNA-binding abilities P Klus, B Bolognesi, F Agostini, D Marchese, A Zanzoni, GG Tartaglia Bioinformatics 30 (11), 1601-1608, 2014 | 64 | 2014 |
Principles of self-organization in biological pathways: a hypothesis on the autogenous association of alpha-synuclein A Zanzoni, D Marchese, F Agostini, B Bolognesi, D Cirillo, M Botta-Orfila, ... Nucleic acids research 41 (22), 9987-9998, 2013 | 61 | 2013 |
Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid β self-assembly A Abelein, B Bolognesi, CM Dobson, A Graslund, C Lendel Biochemistry 51 (1), 126-137, 2012 | 61 | 2012 |
Intrinsic determinants of neurotoxic aggregate formation by the amyloid β peptide AC Brorsson, B Bolognesi, GG Tartaglia, SL Shammas, G Favrin, I Watson, ... Biophysical journal 98 (8), 1677-1684, 2010 | 61 | 2010 |
X-inactivation: quantitative predictions of protein interactions in the Xist network F Agostini, D Cirillo, B Bolognesi, GG Tartaglia Nucleic acids research 41 (1), e31-e31, 2013 | 56 | 2013 |
The genetic landscape for amyloid beta fibril nucleation accurately discriminates familial Alzheimer’s disease mutations M Seuma, AJ Faure, M Badia, B Lehner, B Bolognesi elife 10, e63364, 2021 | 39 | 2021 |
Methods and models in neurodegenerative and systemic protein aggregation diseases AC Brorsson, JR Kumita, I MacLeod, B Bolognesi, E Speretta, LM Luheshi, ... Front. Biosci 15 (1), 373-396, 2010 | 34 | 2010 |
An atlas of amyloid aggregation: the impact of substitutions, insertions, deletions and truncations on amyloid beta fibril nucleation M Seuma, B Lehner, B Bolognesi Nature Communications 13 (1), 7084, 2022 | 29 | 2022 |
Single Point Mutations Induce a Switch in the Molecular Mechanism of the Aggregation of the Alzheimer’s Disease Associated Aβ42 Peptide B Bolognesi, SIA Cohen, P Aran Terol, EK Esbjörner, S Giorgetti, ... ACS Chemical Biology 9 (2), 378-382, 2014 | 28 | 2014 |