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Hu Zheng
Hu Zheng
Verified email at whu.edu.cn
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Year
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Z Hu, D Zhu, W Wang, W Li, W Jia, X Zeng, W Ding, L Yu, X Wang, ...
Nature genetics 47 (2), 158-163, 2015
4922015
The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implications
Z Hu, D Ma
Cancer medicine 7 (10), 5217-5236, 2018
3042018
Disruption of HPV16-E7 by CRISPR/Cas system induces apoptosis and growth inhibition in HPV16 positive human cervical cancer cells
Z Hu, L Yu, D Zhu, W Ding, X Wang, C Zhang, L Wang, X Jiang, H Shen, ...
BioMed research international 2014, 2014
2132014
TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy
Z Hu, W Ding, D Zhu, L Yu, X Jiang, X Wang, C Zhang, L Wang, T Ji, D Liu, ...
The Journal of clinical investigation 125 (1), 425-436, 2015
1232015
LNMICC promotes nodal metastasis of cervical cancer by reprogramming fatty acid metabolism
C Shang, W Wang, Y Liao, Y Chen, T Liu, Q Du, J Huang, Y Liang, J Liu, ...
Cancer research 78 (4), 877-890, 2018
1112018
Hyperbranched poly (β-amino ester) based polyplex nanopaticles for delivery of CRISPR/Cas9 system and treatment of HPV infection associated cervical cancer
X Gao, Z Jin, X Tan, C Zhang, C Zou, W Zhang, J Ding, BC Das, ...
Journal of controlled release 321, 654-668, 2020
692020
Zinc Finger Nucleases Targeting the Human Papillomavirus E7 Oncogene Induce E7 Disruption and a Transformed Phenotype in HPV16/18-Positive Cervical …
W Ding, Z Hu, D Zhu, X Jiang, L Yu, X Wang, C Zhang, L Wang, T Ji, K Li, ...
Clinical cancer research 20 (24), 6495-6503, 2014
652014
HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer
C Cao, P Hong, X Huang, D Lin, G Cao, L Wang, B Feng, P Wu, H Shen, ...
Journal of genetics and genomics 47 (8), 437-450, 2020
492020
Amplification and overexpression of TP63 and MYC as biomarkers for transition of cervical intraepithelial neoplasia to cervical cancer.
D Zhu, XH Jiang, YH Jiang, WC Ding, C Zhang, H Shen, XL Wang, D Ma, ...
International Journal of Gynecologic Cancer 24 (4), 643-648, 2014
42*2014
Fibulin-5 is down-regulated in urothelial carcinoma of bladder and inhibits growth and invasion of human bladder cancer cell line 5637
Z Hu, Q Ai, H Xu, X Ma, H Li, T Shi, C Wang, D Gong, X Zhang
Urologic Oncology: Seminars and Original Investigations 29 (4), 430-435, 2011
422011
Periostin+cancer‐associated fibroblasts promote lymph node metastasis by impairing the lymphatic endothelial barriers in cervical squamous cell carcinoma
WF Wei, XJ Chen, LJ Liang, L Yu, XG Wu, CF Zhou, ZC Wang, LS Fan, ...
Molecular Oncology 15 (1), 210-227, 2021
342021
Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer
TY Liu, J Chen, CL Shang, HW Shen, JM Huang, YC Liang, W Wang, ...
Journal of Experimental & Clinical Cancer Research 35, 1-20, 2016
342016
In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system
Y Chen, H Jiang, T Wang, D He, R Tian, Z Cui, X Tian, Q Gao, X Ma, ...
Antiviral Research 178, 104794, 2020
332020
The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy
Z Cui, H Liu, H Zhang, Z Huang, R Tian, L Li, W Fan, Y Chen, L Chen, ...
Molecular Therapy-Nucleic Acids 26, 1466-1478, 2021
282021
FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity
Z Cui, R Tian, Z Huang, Z Jin, L Li, J Liu, Z Huang, H Xie, D Liu, H Mo, ...
Nature Communications 13 (1), 1425, 2022
252022
Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles
Carcinogenesis 40 (10), 1220–1228, 2019
242019
An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy
G Niu, Z Jin, C Zhang, D He, X Gao, C Zou, W Zhang, J Ding, BC Das, ...
EBioMedicine 58, 2020
152020
Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells
R Tian, J Liu, W Fan, R Li, Z Cui, Z Jin, Z Huang, H Xie, L Li, Z Huang, ...
Molecular Therapy-Oncolytics 24, 171-179, 2022
142022
A fifteen‐gene classifier to predict neoadjuvant chemotherapy responses in patients with stage IB to IIB squamous cervical cancer
X Tian, X Wang, Z Cui, J Liu, X Huang, C Shi, M Zhang, T Liu, X Du, R Li, ...
Advanced Science 8 (10), 2001978, 2021
122021
Cytological immunostaining of HMGA2, LRP1B, and TP63 as potential biomarkers for triaging human papillomavirus-positive women
Y Jiang, C Zhu, D He, Q Gao, X Tian, X Ma, J Wu, BC Das, K Severinov, ...
Translational Oncology 12 (7), 959-967, 2019
112019
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