| Molecular mechanisms of somatic hypermutation and class switch recombination SP Methot, JM Di Noia Advances in immunology 133, 37-87, 2017 | 277 | 2017 |
| Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance J Padeken, SP Methot, SM Gasser Nature Reviews Molecular Cell Biology 23 (9), 623-640, 2022 | 150 | 2022 |
| Guanine-rich RNAs and DNAs that bind heme robustly catalyze oxygen transfer reactions LCH Poon, SP Methot, W Morabi-Pazooki, F Pio, AJ Bennet, D Sen Journal of the American Chemical Society 133 (6), 1877-1884, 2011 | 125 | 2011 |
| PRMT5 is essential for B cell development and germinal center dynamics LC Litzler, A Zahn, AP Meli, S Hébert, AM Patenaude, SP Methot, ... Nature communications 10 (1), 22, 2019 | 74 | 2019 |
| Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination A Zahn, AK Eranki, AM Patenaude, SP Methot, H Fifield, EM Cortizas, ... Proceedings of the National Academy of Sciences 111 (11), E988-E997, 2014 | 62 | 2014 |
| Optimal functional levels of activation‐induced deaminase specifically require the Hsp40 DnaJa1 A Orthwein, A Zahn, SP Methot, D Godin, SG Conticello, K Terada, ... The EMBO journal 31 (3), 679-691, 2012 | 61 | 2012 |
| Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm SP Methot, LC Litzler, F Trajtenberg, A Zahn, F Robert, J Pelletier, ... Journal of Experimental Medicine 212 (4), 581-596, 2015 | 52 | 2015 |
| Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression J Padeken, P Zeller, B Towbin, I Katic, V Kalck, SP Methot, SM Gasser Genes & development 33 (7-8), 436-451, 2019 | 48 | 2019 |
| A licensing step links AID to transcription elongation for mutagenesis in B cells SP Methot, LC Litzler, PG Subramani, AK Eranki, H Fifield, AM Patenaude, ... Nature communications 9 (1), 1248, 2018 | 46 | 2018 |
| A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching Y Hu, I Ericsson, K Torseth, SP Methot, O Sundheim, NB Liabakk, ... Journal of molecular biology 425 (2), 424-443, 2013 | 45 | 2013 |
| H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity SP Methot, J Padeken, G Brancati, P Zeller, CE Delaney, D Gaidatzis, ... Nature cell biology 23 (11), 1163-1175, 2021 | 39 | 2021 |
| Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65 CE Delaney, SP Methot, M Guidi, I Katic, SM Gasser, J Padeken Journal of Cell Biology 218 (3), 820-838, 2019 | 24 | 2019 |
| Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression J Padeken, S Methot, P Zeller, CE Delaney, V Kalck, SM Gasser Genes & development 35 (1-2), 82-101, 2021 | 20 | 2021 |
| Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin JHE Baker, AH Kyle, KL Bartels, SP Methot, EJ Flanagan, A Balbirnie, ... PLoS One 8 (10), e76832, 2013 | 15 | 2013 |
| AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms PE Morande, XJ Yan, J Sepulveda, N Seija, ME Marquez, N Sotelo, ... Blood, The Journal of the American Society of Hematology 138 (3), 246-258, 2021 | 13 | 2021 |
| SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity CE Delaney, SP Methot, V Kalck, J Seebacher, D Hess, SM Gasser, ... Nature structural & molecular biology 29 (2), 85-96, 2022 | 11 | 2022 |
| Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice LC Litzler, A Zahn, KL Dionne, A Sprumont, SR Ferreira, MRF Slattery, ... Journal of Experimental Medicine 220 (9), e20220381, 2023 | 2 | 2023 |
| Pharmacological manipulation of AID SP Methot, JM Di Noia Oncotarget 6 (29), 26550, 2015 | 2 | 2015 |
| Author Correction: SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity CE Delaney, SP Methot, V Kalck, J Seebacher, D Hess, SM Gasser, ... Nature Structural & Molecular Biology 29 (5), 502, 2022 | | 2022 |
| How Heterochromatin Ensures Genome Stability and Tissue Specific Gene Expression SP Methot, J Padeken, G Brancati, P Zeller, D Gaidatzis, H Grosshans, ... 한국미생물학회 학술대회논문집, 35-35, 2021 | | 2021 |
Javier M Di NoiaInstitute de Recherches Cliniques de Montreal (IRCM)Verified email at ircm.qc.ca
