Alan H Lazarus
Alan H Lazarus
Canadian Blood Services & The Li Ka Shing Institute of St. Michael's Hospital & The University of
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Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.
MJ Rapoport, A Jaramillo, D Zipris, AH Lazarus, DV Serreze, EH Leiter, ...
The Journal of experimental medicine 178 (1), 87-99, 1993
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
R Aslam, ER Speck, M Kim, AR Crow, KWA Bang, FP Nestel, H Ni, ...
Blood 107 (2), 637-641, 2006
Intravenous immunoglobulin ameliorates ITP via activating Fcγ receptors on dendritic cells
V Siragam, AR Crow, D Brinc, S Song, J Freedman, AH Lazarus
Nature medicine 12 (6), 688-692, 2006
Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk
A Podolanczuk, AH Lazarus, AR Crow, E Grossbard, JB Bussel
Blood, The Journal of the American Society of Hematology 113 (14), 3154-3160, 2009
A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy
L Chow, R Aslam, ER Speck, M Kim, N Cridland, ML Webster, P Chen, ...
Blood, The Journal of the American Society of Hematology 115 (6), 1247-1253, 2010
IVIg-mediated amelioration of murine ITP via FcγRIIB is independent of SHIP1, SHP-1, and Btk activity
AR Crow, S Song, J Freedman, CD Helgason, RK Humphries, ...
Blood 102 (2), 558-560, 2003
IVIg inhibits reticuloendothelial system function and ameliorates murine passive‐immune thrombocytopenia independent of anti‐idiotype reactivity
AR Crow, S Song, JW Semple, J Freedman, AH Lazarus
British journal of haematology 115 (3), 679-686, 2001
Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils
IK Campbell, S Miescher, DR Branch, PJ Mott, AH Lazarus, D Han, ...
The Journal of Immunology 192 (11), 5031-5038, 2014
Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of …
D Zipris, AH Lazarus, AR Crow, M Hadzija, TL Delovitch
Journal of immunology (Baltimore, Md.: 1950) 146 (11), 3763-3771, 1991
Can antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease?
V Siragam, D Brinc, AR Crow, S Song, J Freedman, AH Lazarus
The Journal of clinical investigation 115 (1), 155-160, 2005
Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation.
MJ Rapoport, AH Lazarus, A Jaramillo, E Speck, TL Delovitch
The Journal of experimental medicine 177 (4), 1221-1226, 1993
The mechanisms of action of intravenous immunoglobulin and polyclonal anti-d immunoglobulin in the amelioration of immune thrombocytopenic purpura: what do we really know?
AR Crow, AH Lazarus
Transfusion medicine reviews 22 (2), 103-116, 2008
Intravenous immunoglobulin inhibits anti‐glycoprotein IIb‐induced platelet apoptosis in a murine model of immune thrombocytopenia
V Leytin, S Mykhaylov, AF Starkey, DJ Allen, H Lau, H Ni, JW Semple, ...
British journal of haematology 133 (1), 78-82, 2006
Antigen-induced B lymphocyte activation involves the p21ras and ras. GAP signaling pathway.
AH Lazarus, K Kawauchi, MJ Rapoport, TL Delovitch
The Journal of experimental medicine 178 (5), 1765-1769, 1993
A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy
H Ni, P Chen, CM Spring, E Sayeh, JW Semple, AH Lazarus, RO Hynes, ...
Blood 107 (7), 2976-2983, 2006
Monoclonal IgG can ameliorate immune thrombocytopenia in a murine model of ITP: an alternative to IVIG
S Song, AR Crow, J Freedman, AH Lazarus
Blood, The Journal of the American Society of Hematology 101 (9), 3708-3713, 2003
Mechanism of action of IVIG and anti-D in ITP
AH Lazarus, AR Crow
Transfusion and apheresis science 28 (3), 249-255, 2003
A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?
AR Crow, S Song, JW Semple, J Freedman, AH Lazarus
Blood 109 (1), 155-158, 2007
Role of Fcγ receptors in the pathogenesis and treatment of idiopathic thrombocytopenic purpura
AR Crow, AH Lazarus
Journal of pediatric hematology/oncology 25, S14-S18, 2003
Preanalytical requirements for flow cytometric evaluation of platelet activation: choice of anticoagulant
Mody, Lazarus, Semple
Transfusion Medicine 9 (2), 147-154, 1999
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