| Fungal metabolites as pharmaceuticals AM Beekman, RA Barrow Australian Journal of Chemistry 67 (6), 827-843, 2014 | 70 | 2014 |
| Small‐molecule and peptide inhibitors of the pro‐survival protein Mcl‐1 AM Beekman, LA Howell ChemMedChem 11 (8), 802-813, 2016 | 51 | 2016 |
| Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4 SC Mills, L Howell, A Beekman, L Stokes, A Mueller Cellular signalling 42, 88-96, 2018 | 24 | 2018 |
| Syntheses of the fungal metabolites boletopsins 7, 11, and 12 from the Papua New Guinea medicinal mushroom Boletopsis sp. AM Beekman, RA Barrow The Journal of organic chemistry 79 (3), 1017-1024, 2014 | 23 | 2014 |
| Syntheses of the fungal metabolites boletopsins 7, 11, and 12 from the Papua New Guinea medicinal mushroom Boletopsis sp. AM Beekman, RA Barrow The Journal of organic chemistry 79 (3), 1017-1024, 2014 | 23 | 2014 |
| Identification of Boletopsin 11 and 12, Antibiotics from the Traditionally Used Fungus Boletopsis sp. SW Wossa, AM Beekman, P Ma, O Kevo, RA Barrow Asian Journal of Organic Chemistry 2 (7), 565-567, 2013 | 22 | 2013 |
| First syntheses of the biologically active fungal metabolites pestalotiopsones A, B, C and F AM Beekman, EC Martinez, RA Barrow Organic & Biomolecular Chemistry 11 (7), 1109-1115, 2013 | 22 | 2013 |
| Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design AM Beekman, MMD Cominetti, SJ Walpole, S Prabhu, MA O'Connell, ... Chemical Science 10 (16), 4502-4508, 2019 | 21 | 2019 |
| Identification of Small‐Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia‐1 (Mcl‐1) AM Beekman, MA O'Connell, LA Howell ChemMedChem 11 (8), 840-844, 2016 | 19 | 2016 |
| Peptide‐Directed Binding for the Discovery of Modulators of α‐Helix‐Mediated Protein–Protein Interactions: Proof‐of‐Concept Studies with the Apoptosis Regulator Mcl‐1 AM Beekman, MA O'Connell, LA Howell Angewandte Chemie 129 (35), 10582-10586, 2017 | 15 | 2017 |
| Ravynic acid, an antibiotic polyeneyne tetramic acid from Penicillium sp. elucidated through synthesis JD Myrtle, AM Beekman, RA Barrow Organic & Biomolecular Chemistry 14 (35), 8253-8260, 2016 | 15 | 2016 |
| Cleavage of Catechol Monoalkyl Ethers by Aluminum Triiodide–Dimethyl Sulfoxide D Sang, J Tian, X Tu, Z He, M Yao Synthesis 51 (03), 704-712, 2019 | 14 | 2019 |
| Discovery and synthesis of Boletopsins 13 and 14, brominated fungal metabolites of terrestrial origin AM Beekman, SW Wossa, O Kevo, P Ma, RA Barrow Journal of natural products 78 (8), 2133-2135, 2015 | 13 | 2015 |
| Peptide directed phthalocyanine–gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers ZR Goddard, AM Beekman, MMD Cominetti, MA O'Connell, I Chambrier, ... RSC Medicinal Chemistry 12 (2), 288-292, 2021 | 12 | 2021 |
| Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors W Piyasirananda, A Beekman, A Ganesan, S Bidula, L Stokes Molecular pharmacology 99 (2), 163-174, 2021 | 11 | 2021 |
| Syntheses of cytosporones A, C, J, K, and N, metabolites from medicinal fungi AM Beekman, RA Barrow Australian Journal of Chemistry 68 (10), 1583-1592, 2015 | 11 | 2015 |
| Stereochemical assignment of the fungal metabolites pestalotiopsones D and E through enantiopure synthesis AM Beekman, RA Barrow Journal of natural products 76 (11), 2054-2059, 2013 | 11 | 2013 |
| A Peptide–Duocarmycin Conjugate Targeting the Thomsen-Friedenreich Antigen Has Potent and Selective Antitumor Activity OC Cartwright, AM Beekman, MMD Cominetti, DA Russell, M Searcey Bioconjugate Chemistry 31 (7), 1745-1749, 2020 | 7 | 2020 |
| Duocarmycins as antibody–drug conjugate (ADC) payloads AM Beekman, M Cominetti, M Searcey | 5 | 2019 |
| A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase AM Beekman, MMD Cominetti, OC Cartwright, DL Boger, M Searcey MedChemComm 10 (12), 2170-2174, 2019 | 5 | 2019 |
Lesley Ann HowellLecturer in Pharmaceutical/Medicinal Chemistry, Queen Mary, University of LondonVerified email at qmul.ac.uk
