Reduced physical activity and risk of chronic disease: the biology behind the consequences FW Booth, MJ Laye, SJ Lees, RS Rector, JP Thyfault European journal of applied physiology 102 (4), 381-390, 2008 | 236 | 2008 |
Fundamental questions about genes, inactivity, and chronic diseases FW Booth, SJ Lees Physiological genomics 28 (2), 146-157, 2007 | 198 | 2007 |
Sedentary death syndrome SJ Lees, FW Booth Canadian Journal of Applied Physiology 29 (4), 447-460, 2004 | 155 | 2004 |
Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells EAIF Queiroz, S Puukila, R Eichler, SC Sampaio, HL Forsyth, SJ Lees, ... PloS one 9 (5), e98207, 2014 | 148 | 2014 |
Physically active subjects should be the control group FW Booth, SJ Lees Medicine and Science in Sports and Exercise 38 (3), 405, 2006 | 123 | 2006 |
Calcineurin activation influences muscle phenotype in a muscle-specific fashion RJ Talmadge, JS Otis, MR Rittler, ND Garcia, SR Spencer, SJ Lees, ... BMC cell biology 5 (1), 28, 2004 | 102 | 2004 |
Sirt1 increases skeletal muscle precursor cell proliferation CR Rathbone, FW Booth, SJ Lees European journal of cell biology 88 (1), 35-44, 2009 | 97 | 2009 |
Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia BT Steffen, SJ Lees, FW Booth Journal of applied physiology 105 (6), 1950-1958, 2008 | 67 | 2008 |
Glycogen and glycogen phosphorylase associated with sarcoplasmic reticulum: effects of fatiguing activity SJ Lees, PD Franks, EE Spangenburg, JH Williams Journal of Applied Physiology 91 (4), 1638-1644, 2001 | 66 | 2001 |
Age-associated decrease in muscle precursor cell differentiation SJ Lees, CR Rathbone, FW Booth American Journal of Physiology-Cell Physiology 290 (2), C609-C615, 2006 | 57 | 2006 |
Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat RT Morris, MJ Laye, SJ Lees, RS Rector, JP Thyfault, FW Booth Journal of Applied Physiology 104 (3), 708-715, 2008 | 52 | 2008 |
Pro-inflammatory mediation of myoblast proliferation JS Otis, S Niccoli, N Hawdon, JL Sarvas, MA Frye, AJ Chicco, SJ Lees PloS one 9 (3), e92363, 2014 | 51 | 2014 |
The IL-6 paradox: context dependent interplay of SOCS3 and AMPK JL Sarvas, N Khaper, SJ Lees Journal of diabetes & metabolism, 2013 | 48 | 2013 |
Physical inactivity is a disease S Lees, F Booth World review of nutrition and dietetics 95 (R), 73, 2005 | 47 | 2005 |
FoxO3a preferentially induces p27Kip1 expression while impairing muscle precursor cell‐cycle progression CR Rathbone, FW Booth, SJ Lees Muscle & Nerve: Official Journal of the American Association of …, 2008 | 41 | 2008 |
Age-dependent FOXO regulation of p27Kip1 expression via a conserved binding motif in rat muscle precursor cells SJ Lees, TE Childs, FW Booth American Journal of Physiology-Cell Physiology 295 (5), C1238-C1246, 2008 | 38 | 2008 |
Muscle precursor cells isolated from aged rats exhibit an increased tumor necrosis factor‐α response SJ Lees, KA Zwetsloot, FW Booth Aging cell 8 (1), 26-35, 2009 | 33 | 2009 |
Skeletal muscle sarcoplasmic reticulum glycogen status influences Ca2+ uptake supported by endogenously synthesized ATP SJ Lees, JH Williams American Journal of Physiology-Cell Physiology 286 (1), C97-C104, 2004 | 33 | 2004 |
p21Cip1 expression is increased in ambient oxygen, compared to estimated physiological (5%) levels in rat muscle precursor cell culture SJ Lees, TE Childs, FW Booth Cell proliferation 41 (2), 193-207, 2008 | 28 | 2008 |
Fibroblast growth factor 2‐stimulated proliferation is lower in muscle precursor cells from old rats SS Jump, TE Childs, KA Zwetsloot, FW Booth, SJ Lees Experimental physiology 94 (6), 739-748, 2009 | 24 | 2009 |