| Reduced physical activity and risk of chronic disease: the biology behind the consequences FW Booth, MJ Laye, SJ Lees, RS Rector, JP Thyfault European journal of applied physiology 102 (4), 381-390, 2008 | 292 | 2008 |
| Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells EAIF Queiroz, S Puukila, R Eichler, SC Sampaio, HL Forsyth, SJ Lees, ... PloS one 9 (5), e98207, 2014 | 253 | 2014 |
| Fundamental questions about genes, inactivity, and chronic diseases FW Booth, SJ Lees Physiological genomics, 2007 | 250 | 2007 |
| Sedentary death syndrome SJ Lees, FW Booth Canadian Journal of Applied Physiology 29 (4), 447-460, 2004 | 205 | 2004 |
| Physically active subjects should be the control group FW Booth, SJ Lees Medicine and Science in Sports and Exercise 38 (3), 405, 2006 | 143 | 2006 |
| Sirt1 increases skeletal muscle precursor cell proliferation CR Rathbone, FW Booth, SJ Lees European journal of cell biology 88 (1), 35-44, 2009 | 120 | 2009 |
| Calcineurin activation influences muscle phenotype in a muscle-specific fashion RJ Talmadge, JS Otis, MR Rittler, ND Garcia, SR Spencer, SJ Lees, ... BMC cell biology 5 (1), 1-12, 2004 | 111 | 2004 |
| Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia BT Steffen, SJ Lees, FW Booth Journal of applied physiology 105 (6), 1950-1958, 2008 | 90 | 2008 |
| Pro-inflammatory mediation of myoblast proliferation JS Otis, S Niccoli, N Hawdon, JL Sarvas, MA Frye, AJ Chicco, SJ Lees PloS one 9 (3), e92363, 2014 | 87 | 2014 |
| Age-associated decrease in muscle precursor cell differentiation SJ Lees, CR Rathbone, FW Booth American Journal of Physiology-Cell Physiology 290 (2), C609-C615, 2006 | 73 | 2006 |
| Glycogen and glycogen phosphorylase associated with sarcoplasmic reticulum: effects of fatiguing activity SJ Lees, PD Franks, EE Spangenburg, JH Williams Journal of Applied Physiology 91 (4), 1638-1644, 2001 | 72 | 2001 |
| Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat RT Morris, MJ Laye, SJ Lees, RS Rector, JP Thyfault, FW Booth Journal of Applied Physiology 104 (3), 708-715, 2008 | 65 | 2008 |
| The IL-6 paradox: context dependent interplay of SOCS3 and AMPK JL Sarvas, N Khaper, SJ Lees Journal of diabetes & metabolism, 2013 | 62 | 2013 |
| Physical inactivity is a disease S Lees, F Booth World review of nutrition and dietetics 95 (R), 73, 2005 | 55 | 2005 |
| FoxO3a preferentially induces p27Kip1 expression while impairing muscle precursor cell‐cycle progression CR Rathbone, FW Booth, SJ Lees Muscle & Nerve: Official Journal of the American Association of …, 2008 | 47 | 2008 |
| Age-dependent FOXO regulation of p27Kip1 expression via a conserved binding motif in rat muscle precursor cells SJ Lees, TE Childs, FW Booth American Journal of Physiology-Cell Physiology 295 (5), C1238-C1246, 2008 | 43 | 2008 |
| Muscle precursor cells isolated from aged rats exhibit an increased tumor necrosis factor‐α response SJ Lees, KA Zwetsloot, FW Booth Aging cell 8 (1), 26-35, 2009 | 40 | 2009 |
| Ionizing radiation exposure during pregnancy: effects on postnatal development and life S Sreetharan, C Thome, S Tharmalingam, DE Jones, AV Kulesza, ... Radiation research 187 (6), 647-658, 2017 | 39 | 2017 |
| Skeletal muscle sarcoplasmic reticulum glycogen status influences Ca2+ uptake supported by endogenously synthesized ATP SJ Lees, JH Williams American Journal of Physiology-Cell Physiology 286 (1), C97-C104, 2004 | 35 | 2004 |
| Searching for novel PET radiotracers: imaging cardiac perfusion, metabolism and inflammation CQ Davidson, CP Phenix, TC Tai, N Khaper, SJ Lees American Journal of Nuclear Medicine and Molecular Imaging 8 (3), 200, 2018 | 34 | 2018 |
