Leanne Stokes
Leanne Stokes
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The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease
R Bartlett, L Stokes, R Sluyter
Pharmacological reviews 66 (3), 638-675, 2014
The human P2X7 receptor and its role in innate immunity
JS Wiley, R Sluyter, BJ Gu, L Stokes, SJ Fuller
Tissue antigens 78 (5), 321-332, 2011
Two haplotypes of the P2X7 receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion
L Stokes, SJ Fuller, R Sluyter, KK Skarratt, BJ Gu, JS Wiley
The FASEB Journal 24 (8), 2916-2927, 2010
Characterization of a selective and potent antagonist of human P2X7 receptors, AZ11645373
L Stokes, LH Jiang, L Alcaraz, J Bent, K Bowers, M Fagura, M Furber, ...
British journal of pharmacology 149 (7), 880-887, 2006
Significance of P2X7 receptor variants to human health and disease
R Sluyter, L Stokes
Recent Patents on DNA & Gene Sequences (Discontinued) 5 (1), 41-54, 2011
Genetics of the P2X7 receptor and human disease
SJ Fuller, L Stokes, KK Skarratt, BJ Gu, JS Wiley
Purinergic signalling 5, 257-262, 2009
Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor
KR Vaughan, L Stokes, LR Prince, HM Marriott, S Meis, MU Kassack, ...
The Journal of Immunology 179 (12), 8544-8553, 2007
P2X4 receptor function in the nervous system and current breakthroughs in pharmacology
L Stokes, JA Layhadi, L Bibic, K Dhuna, SJ Fountain
Frontiers in pharmacology 8, 291, 2017
Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major α pore-forming and auxiliary β-subunits
L Stokes, J Gordon, G Grafton
Journal of Biological Chemistry 279 (19), 19566-19573, 2004
Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation
BJ Gu, C Rathsam, L Stokes, AB McGeachie, JS Wiley
American Journal of Physiology-Cell Physiology 297 (2), C430-C439, 2009
Calcium channels in lymphocytes
G Grafton, L Thwaite
Immunology 104 (2), 119, 2001
Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures
NR Jørgensen, LB Husted, KK Skarratt, L Stokes, CL Tofteng, T Kvist, ...
European Journal of Human Genetics 20 (6), 675-681, 2012
Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism
A Bhaskaracharya, P Dao-Ung, I Jalilian, M Spildrejorde, KK Skarratt, ...
PloS one 9 (3), e93058, 2014
Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women
A Gartland, KK Skarratt, LJ Hocking, C Parsons, L Stokes, NR Jørgensen, ...
European Journal of Human Genetics 20 (5), 559-564, 2012
P2X receptor characterization and IL‐1/IL‐1Ra release from human endothelial cells
HL Wilson, RW Varcoe, L Stokes, KL Holland, SE Francis, SK Dower, ...
British journal of pharmacology 151 (1), 96-108, 2007
Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term
I Ziko, S De Luca, T Dinan, JM Barwood, L Sominsky, G Cai, R Kenny, ...
Brain, behavior, and immunity 41, 32-43, 2014
A loss-of-function polymorphism in the human P2X4 receptor is associated with increased pulse pressure
L Stokes, K Scurrah, JA Ellis, BA Cromer, KK Skarratt, BJ Gu, SB Harrap, ...
Hypertension 58 (6), 1086-1092, 2011
Purinergic P2Y2 receptors induce increased MCP-1/CCL2 synthesis and release from rat alveolar and peritoneal macrophages
L Stokes, A Surprenant
The Journal of Immunology 179 (9), 6016-6023, 2007
Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation
L Stokes, A Surprenant
European journal of immunology 39 (4), 986-995, 2009
A non-voltage-gated calcium channel with L-type characteristics activated by B cell receptor ligation
G Grafton, L Stokes, KM Toellner, J Gordon
Biochemical pharmacology 66 (10), 2001-2009, 2003
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