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Christian Beausejour
Christian Beausejour
Verified email at umontreal.ca
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Year
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
FD Urnov, JC Miller, YL Lee, CM Beausejour, JM Rock, S Augustus, ...
Nature 435 (7042), 646-651, 2005
21682005
Reversal of human cellular senescence: roles of the p53 and p16 pathways
CM Beauséjour, A Krtolica, F Galimi, M Narita, SW Lowe, P Yaswen, ...
The EMBO journal, 2003
16702003
An improved zinc-finger nuclease architecture for highly specific genome editing
JC Miller, MC Holmes, J Wang, DY Guschin, YL Lee, I Rupniewski, ...
Nature biotechnology 25 (7), 778-785, 2007
14872007
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
A Lombardo, P Genovese, CM Beausejour, S Colleoni, YL Lee, KA Kim, ...
Nature biotechnology 25 (11), 1298-1306, 2007
11422007
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
M Fumagalli, F Rossiello, M Clerici, S Barozzi, D Cittaro, JM Kaplunov, ...
Nature cell biology 14 (4), 355-365, 2012
8822012
L1 drives IFN in senescent cells and promotes age-associated inflammation
M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ...
Nature 566 (7742), 73-78, 2019
7832019
Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
JP Coppé, K Kauser, J Campisi, CM Beauséjour
Journal of Biological Chemistry 281 (40), 29568-29574, 2006
6682006
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
F Rodier, DP Muñoz, R Teachenor, V Chu, O Le, D Bhaumik, JP Coppé, ...
Journal of cell science 124 (1), 68-81, 2011
5972011
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1
K Itahana, Y Zou, Y Itahana, JL Martinez, C Beausejour, JJL Jacobs, ...
Molecular and cellular biology 23 (1), 389-401, 2003
5852003
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen
JP Coppe, CK Patil, F Rodier, A Krtolica, CM Beausejour, S Parrinello, ...
PloS one 5 (2), e9188, 2010
4912010
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
AR Davalos, M Kawahara, GK Malhotra, N Schaum, J Huang, U Ved, ...
Journal of Cell Biology 201 (4), 613-629, 2013
4382013
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
P Sapieha, M Sirinyan, D Hamel, K Zaniolo, JS Joyal, JH Cho, JC Honoré, ...
Nature medicine 14 (10), 1067-1076, 2008
4122008
TIN2 mediates functions of TRF2 at human telomeres
S Kim, C Beausejour, AR Davalos, P Kaminker, SJ Heo, J Campisi
Journal of biological chemistry 279 (42), 43799-43804, 2004
3192004
Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A
JS Joyal, N Sitaras, F Binet, JC Rivera, A Stahl, K Zaniolo, Z Shao, ...
Blood, The Journal of the American Society of Hematology 117 (22), 6024-6035, 2011
2032011
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status
ONL Le, F Rodier, F Fontaine, JP Coppe, J Campisi, J DeGregori, ...
Aging cell 9 (3), 398-409, 2010
1812010
Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming
S Selleri, P Bifsha, S Civini, C Pacelli, MM Dieng, W Lemieux, P Jin, ...
Oncotarget 7 (21), 30193, 2016
1552016
Balancing regeneration and cancer
CM Beausejour, J Campisi
Nature 443 (7110), 404-405, 2006
1372006
Bone marrow-derived cells: the influence of aging and cellular senescence
C Beausejour
Bone marrow-derived progenitors, 67-88, 2007
1062007
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition
S Crespo-Garcia, PR Tsuruda, A Dejda, RD Ryan, F Fournier, SY Chaney, ...
Cell metabolism 33 (4), 818-832. e7, 2021
862021
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
S Kim, AR Davalos, SJ Heo, F Rodier, Y Zou, C Beausejour, P Kaminker, ...
The Journal of cell biology 181 (3), 447-460, 2008
832008
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