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John Tolsma
John Tolsma
RES Group
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Title
Cited by
Cited by
Year
Efficient sensitivity analysis of large-scale differential-algebraic systems
WF Feehery, JE Tolsma, PI Barton
Applied Numerical Mathematics 25 (1), 41-54, 1997
3051997
DAEPACK: An open modeling environment for legacy models
J Tolsma, PI Barton
Industrial & Engineering Chemistry Research 39 (6), 1826-1839, 2000
1332000
Optimal design and operation of a natural gas tri-reforming reactor for DME synthesis
W Cho, T Song, A Mitsos, JT McKinnon, GH Ko, JE Tolsma, D Denholm, ...
Catalysis Today 139 (4), 261-267, 2009
1322009
On upgrading the numerics in combustion chemistry codes
DA Schwer, JE Tolsma, WH Green Jr, PI Barton
Combustion and Flame 128 (3), 270-291, 2002
902002
Rigorous valid ranges for optimally reduced kinetic models
OO Oluwole, B Bhattacharjee, JE Tolsma, PI Barton, WH Green
Combustion and Flame 146 (1-2), 348-365, 2006
822006
On computational differentiation
JE Tolsma, PI Barton
Computers & chemical engineering 22 (4-5), 475-490, 1998
751998
Bridging the gap between in vitro and in vivo: dose and schedule predictions for the ATR inhibitor AZD6738
S Checkley, L MacCallum, J Yates, P Jasper, H Luo, J Tolsma, ...
Scientific reports 5 (1), 1-12, 2015
672015
Rapid method to determine intracellular drug concentrations in cellular uptake assays: application to metformin in organic cation transporter 1–transfected human embryonic …
HC Chien, AA Zur, TS Maurer, SW Yee, J Tolsma, P Jasper, DO Scott, ...
Drug Metabolism and Disposition 44 (3), 356-364, 2016
612016
Hidden discontinuities and parametric sensitivity calculations
JE Tolsma, PI Barton
SIAM Journal on Scientific Computing 23 (6), 1861-1874, 2002
592002
Preclinical to clinical translation of antibody-drug conjugates using PK/PD modeling: a retrospective analysis of inotuzumab ozogamicin
AM Betts, N Haddish-Berhane, J Tolsma, P Jasper, LE King, Y Sun, ...
The AAPS journal 18, 1101-1116, 2016
532016
Construction of convex relaxations using automated code generation techniques
EP Gatzke, JE Tolsma, PI Barton
Optimization and Engineering 3, 305-326, 2002
522002
Symbolic incorporation of external procedures into process modeling environments
JE Tolsma, JA Clabaugh, PI Barton
Industrial & engineering chemistry research 41 (16), 3867-3876, 2002
492002
Quantitative systems pharmacology modeling of acid sphingomyelinase deficiency and the enzyme replacement therapy olipudase alfa is an innovative tool for linking …
CD Kaddi, B Niesner, R Baek, P Jasper, J Pappas, J Tolsma, J Li, ...
CPT: Pharmacometrics & Systems Pharmacology 7 (7), 442-452, 2018
272018
Computation of heteroazeotropes. Part I: Theory
JE Tolsma, PI Barton
Chemical engineering science 55 (18), 3817-3834, 2000
252000
Systems pharmacology model of gastrointestinal damage predicts species differences and optimizes clinical dosing schedules
H Shankaran, A Cronin, J Barnes, P Sharma, J Tolsma, P Jasper, ...
CPT: Pharmacometrics & Systems Pharmacology 7 (1), 26-33, 2018
202018
Computation of heteroazeotropes. Part II: Efficient calculation of changes in phase equilibrium structure
JE Tolsma, PI Barton
Chemical engineering science 55 (18), 3835-3853, 2000
182000
A quantitative systems pharmacology model of Gaucher disease type 1 provides mechanistic insight into the response to substrate reduction therapy with eliglustat
R Abrams, CD Kaddi, M Tao, RJ Leiser, G Simoni, F Reali, J Tolsma, ...
CPT: pharmacometrics & systems pharmacology 9 (7), 374-383, 2020
172020
Use of translational modeling and simulation for quantitative comparison of PF-06804103, a new generation HER2 ADC, with Trastuzumab-DM1
A Betts, T Clark, P Jasper, J Tolsma, PH van der Graaf, EI Graziani, ...
Journal of Pharmacokinetics and Pharmacodynamics 47, 513-526, 2020
132020
A Physiologically‐Based Pharmacokinetic Model for the Prediction of “Half‐Life Extension” and “Catch and Release” Monoclonal Antibody Pharmacokinetics
HM Jones, J Tolsma, Z Zhang, P Jasper, H Luo, GL Weber, K Wright, ...
CPT: Pharmacometrics & Systems Pharmacology 9 (9), 534-541, 2020
132020
Efficient calculation of sparse Jacobians
JE Tolsma, PI Barton
SIAM Journal on Scientific Computing 20 (6), 2282-2296, 1999
131999
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