Luca Freschi
Luca Freschi
Research fellow, Department of Biomedical informatics, Harvard University
Verified email at
Cited by
Cited by
The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity
L Freschi, AT Vincent, J Jeukens, JG Emond-Rheault, I Kukavica-Ibrulj, ...
Genome biology and evolution 11 (1), 109-120, 2019
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium
L Freschi, J Jeukens, I Kukavica-Ibrulj, B Boyle, MJ Dupont, J Laroche, ...
Frontiers in microbiology 6, 1036, 2015
GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions
MR Farhat, L Freschi, R Calderon, T Ioerger, M Snyder, CJ Meehan, ...
Nature communications 10 (1), 2128, 2019
Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction
ML Chen, A Doddi, J Royer, L Freschi, M Schito, M Ezewudo, IS Kohane, ...
EBioMedicine 43, 356-369, 2019
Genomics of antibiotic‐resistance prediction in Pseudomonas aeruginosa
J Jeukens, L Freschi, I Kukavica‐Ibrulj, JG Emond‐Rheault, NP Tucker, ...
Annals of the New York Academy of Sciences 1435 (1), 5-17, 2019
Population structure, biogeography and transmissibility of Mycobacterium tuberculosis
L Freschi, R Vargas Jr, A Husain, SMM Kamal, A Skrahina, S Tahseen, ...
Nature communications 12 (1), 6099, 2021
Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools
L Freschi, C Bertelli, J Jeukens, MP Moore, I Kukavica-Ibrulj, ...
FEMS microbiology letters 365 (14), fny120, 2018
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes
J Jeukens, I Kukavica-Ibrulj, JG Emond-Rheault, L Freschi, RC Levesque
FEMS Microbiology Letters 364 (18), fnx161, 2017
Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection
I Bianconi, J Jeukens, L Freschi, B Alcalá-Franco, M Facchini, B Boyle, ...
BMC genomics 16 (1), 1-13, 2015
Turnover of protein phosphorylation evolving under stabilizing selection
CR Landry, L Freschi, T Zarin, AM Moses
Frontiers in genetics 5, 245, 2014
A Pan-Genomic Approach to Understand the Basis of Host Adaptation in Achromobacter
J Jeukens, L Freschi, AT Vincent, JG Emond-Rheault, I Kukavica-Ibrulj, ...
Genome Biology and Evolution 9 (4), 1030-1046, 2017
Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida
AT Vincent, MV Trudel, L Freschi, V Nagar, C Gagné-Thivierge, ...
BMC genomics 17 (1), 1-12, 2016
Functional divergence and evolutionary turnover in mammalian phosphoproteomes
L Freschi, M Osseni, CR Landry
PLoS genetics 10 (1), e1004062, 2014
Salmonella enterica Prophage Sequence Profiles Reflect Genome Diversity and Can Be Used for High Discrimination Subtyping
W Mottawea, MO Duceppe, AA Dupras, V Usongo, J Jeukens, L Freschi, ...
Frontiers in microbiology 9, 836, 2018
Comparative analysis of mitochondrial genomes of geographic variants of the gypsy moth, Lymantria dispar, reveals a previously undescribed genotypic entity
A Djoumad, A Nisole, R Zahiri, L Freschi, S Picq, DE Gundersen-Rindal, ...
Scientific Reports 7 (1), 14245, 2017
Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint …
S Lee, P Thebault, L Freschi, S Beaufils, TL Blundell, CR Landry, ...
Journal of Biological Chemistry 287 (8), 5988-6001, 2012
Role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in Mycobacterium tuberculosis complex
R Vargas Jr, L Freschi, A Spitaleri, S Tahseen, I Barilar, S Niemann, ...
Antimicrobial Agents and Chemotherapy 65 (11), 10.1128/aac. 01164-21, 2021
A Multi-Species TaqMan PCR Assay for the Identification of Asian Gypsy Moths (Lymantria spp.) and Other Invasive Lymantriines of Biosecurity Concern to North …
D Stewart, R Zahiri, A Djoumad, L Freschi, J Lamarche, D Holden, ...
PloS one 11 (8), e0160878, 2016
qPCA: a scalable assay to measure the perturbation of protein–protein interactions in living cells
L Freschi, F Torres-Quiroz, AK Dubé, CR Landry
Molecular BioSystems, 2013
Phosphorylation network rewiring by gene duplication
L Freschi, M Courcelles, P Thibault, SW Michnick, CR Landry
Molecular systems biology 7 (1), 504, 2011
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