Ivelin Georgiev
Ivelin Georgiev
Vanderbilt
Verified email at vumc.org - Homepage
Title
Cited by
Cited by
Year
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
T Zhou, I Georgiev, X Wu, ZY Yang, K Dai, A Finzi, Y Do Kwon, JF Scheid, ...
Science 329 (5993), 811-817, 2010
10762010
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ...
Nature 480 (7377), 336-343, 2011
8252011
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
X Wu, T Zhou, J Zhu, B Zhang, I Georgiev, C Wang, X Chen, NS Longo, ...
Science 333 (6049), 1593-1602, 2011
8062011
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ...
Nature 514 (7523), 455-461, 2014
5882014
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ...
Nature 509 (7498), 55-62, 2014
5512014
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
F Klein, R Diskin, JF Scheid, C Gaebler, H Mouquet, IS Georgiev, ...
Cell 153 (1), 126-138, 2013
4042013
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
M Rolland, PT Edlefsen, BB Larsen, S Tovanabutra, E Sanders-Buell, ...
Nature 490 (7420), 417-420, 2012
4012012
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ...
Nature 515 (7525), 138-142, 2014
3602014
Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G
GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ...
Cell 165 (4), 813-826, 2016
2542016
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ...
Immunity 39 (2), 245-258, 2013
2472013
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ...
Nature structural & molecular biology 22 (7), 522, 2015
2282015
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo
RS Rudicell, Y Do Kwon, SY Ko, A Pegu, MK Louder, IS Georgiev, X Wu, ...
Journal of virology 88 (21), 12669-12682, 2014
2042014
Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody
M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ...
Cell 165 (2), 449-463, 2016
1902016
Computational structure-based redesign of enzyme activity
CY Chen, I Georgiev, AC Anderson, BR Donald
Proceedings of the National Academy of Sciences 106 (10), 3764-3769, 2009
1892009
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
IS Georgiev, NA Doria-Rose, T Zhou, Y Do Kwon, RP Staupe, S Moquin, ...
Science 340 (6133), 751-756, 2013
1852013
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Cell 161 (6), 1280-1292, 2015
1832015
Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera
JO Ngwuta, M Chen, K Modjarrad, MG Joyce, M Kanekiyo, A Kumar, ...
Science translational medicine 7 (309), 309ra162-309ra162, 2015
1802015
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
KJ Bar, C Tsao, SS Iyer, JM Decker, Y Yang, M Bonsignori, X Chen, ...
PLoS Pathog 8 (5), e1002721, 2012
1802012
Maturation and diversity of the VRC01-antibody lineage over 15 years of chronic HIV-1 infection
X Wu, Z Zhang, CA Schramm, MG Joyce, Y Do Kwon, T Zhou, Z Sheng, ...
Cell 161 (3), 470-485, 2015
1762015
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ...
Science 352 (6287), 828-833, 2016
1732016
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