H3K36 methylation promotes longevity by enhancing transcriptional fidelity P Sen, W Dang, G Donahue, J Dai, J Dorsey, X Cao, W Liu, K Cao, ... Genes & development 29 (13), 1362-1376, 2015 | 240 | 2015 |
Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching D Wei, X Jiang, L Zhou, J Chen, Z Chen, C He, K Yang, Y Liu, J Pei, L Lai Journal of medicinal chemistry 51 (24), 7882-7888, 2008 | 158 | 2008 |
Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import C He, SK Tsuchiyama, QT Nguyen, EN Plyusnina, SR Terrill, S Sahibzada, ... PLoS genetics 10 (12), e1004860, 2014 | 118 | 2014 |
The yeast replicative aging model C He, C Zhou, BK Kennedy Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (9 …, 2018 | 102 | 2018 |
Translational control of lipogenic enzymes in the cell cycle of synchronous, growing yeast cells HM Blank, R Perez, C He, N Maitra, R Metz, J Hill, Y Lin, CD Johnson, ... The EMBO journal 36 (4), 487-502, 2017 | 71 | 2017 |
Dynamic modeling of human 5-lipoxygenase–inhibitor interactions helps to discover novel inhibitors Y Wu, C He, Y Gao, S He, Y Liu, L Lai Journal of Medicinal Chemistry 55 (6), 2597-2605, 2012 | 58 | 2012 |
Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network C He, Y Wu, Y Lai, Z Cai, Y Liu, L Lai Molecular BioSystems 8 (5), 1585-1594, 2012 | 51 | 2012 |
Proteasomes, Sir2, and Hxk2 form an interconnected aging network that impinges on the AMPK/Snf1-regulated transcriptional repressor Mig1 Y Yao, S Tsuchiyama, C Yang, AL Bulteau, C He, B Robison, M Tsuchiya, ... PLoS genetics 11 (1), e1004968, 2015 | 45 | 2015 |
Benzo [d] isothiazole 1, 1-dioxide derivatives as dual functional inhibitors of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 E Shang, Y Wu, P Liu, Y Liu, W Zhu, X Deng, C He, S He, C Li, L Lai Bioorganic & Medicinal Chemistry Letters 24 (12), 2764-2767, 2014 | 39 | 2014 |
A lipid transfer protein signaling axis exerts dual control of cell-cycle and membrane trafficking systems J Huang, CJ Mousley, L Dacquay, N Maitra, G Drin, C He, ND Ridgway, ... Developmental Cell 44 (3), 378-391. e5, 2018 | 38 | 2018 |
Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity N Maitra, C He, HM Blank, M Tsuchiya, B Schilling, M Kaeberlein, ... Elife 9, e53127, 2020 | 27 | 2020 |
Controlling arachidonic acid metabolic network: from single-to multi-target inhibitors of key enzymes Y Liu, Z Chen, EC Shang, K Yang, DG Wei, L Zhou, XL Jiang, C He, ... Yao xue xue bao= Acta Pharmaceutica Sinica 44 (3), 231-241, 2009 | 12 | 2009 |
Development of 3, 5-dinitrobenzoate-based 5-lipoxygenase inhibitors E Shang, Y Liu, Y Wu, W Zhu, C He, L Lai Bioorganic & Medicinal Chemistry 22 (8), 2396-2402, 2014 | 11 | 2014 |
Translational control of methionine and serine metabolic pathways underpin the paralog-specific phenotypes of Rpl22 ribosomal protein mutants in cell division and replicative … N Maitra, C He, HM Blank, M Tsuchiya, B Schilling, M Kaeberlein, ... bioRxiv, 2020.02. 05.935726, 2020 | 3 | 2020 |
Aging in the Single-Celled Eukaryote, S. cerevisiae C He, BK Kennedy Stem Cell Aging: Mechanisms, Consequences, Rejuvenation, 19-49, 2015 | 2 | 2015 |
Wie Ibuprofen das Altern verlangsamt: neue Erkenntnisse aus Hefen, Würmern und Fliegen C He, SK Tsuchiyama, QT Nguyen, EN Plyusnina, SR Terrill, S Sahibzada, ... Journal Club Schmerzmedizin 4 (02), 74-74, 2015 | | 2015 |
Predicting and modulating aging from cell cycle phenotypes M Polymenis, C He, S Tsuchiyama, Q Ngyen, L Caflisch, B Kennedy YEAST 30, 94-94, 2013 | | 2013 |