Laurie Ailles
Laurie Ailles
Princess Margaret Cancer Centre
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A role for Wnt signalling in self-renewal of haematopoietic stem cells
T Reya, AW Duncan, L Ailles, J Domen, DC Scherer, K Willert, L Hintz, ...
Nature 423 (6938), 409-414, 2003
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
ME Prince, R Sivanandan, A Kaczorowski, GT Wolf, MJ Kaplan, P Dalerba, ...
Proceedings of the National Academy of Sciences 104 (3), 973-978, 2007
Association of reactive oxygen species levels and radioresistance in cancer stem cells
M Diehn, RW Cho, NA Lobo, T Kalisky, MJ Dorie, AN Kulp, D Qian, ...
nature 458 (7239), 780-783, 2009
Granulocyte–macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
CHM Jamieson, LE Ailles, SJ Dylla, M Muijtjens, C Jones, JL Zehnder, ...
New England Journal of Medicine 351 (7), 657-667, 2004
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
A Follenzi, LE Ailles, S Bakovic, M Geuna, L Naldini
Nature genetics 25 (2), 217-222, 2000
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
E Passegué, CHM Jamieson, LE Ailles, IL Weissman
Proceedings of the National Academy of Sciences 100 (suppl_1), 11842-11849, 2003
An immune atlas of clear cell renal cell carcinoma
S Chevrier, JH Levine, VRT Zanotelli, K Silina, D Schulz, M Bacac, ...
Cell 169 (4), 736-749. e18, 2017
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
KS Chan, I Espinosa, M Chao, D Wong, L Ailles, M Diehn, H Gill, ...
Proceedings of the National Academy of Sciences 106 (33), 14016-14021, 2009
Cancer stem cells in solid tumors
LE Ailles, IL Weissman
Current opinion in biotechnology 18 (5), 460-466, 2007
Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo
A Blair, DE Hogge, LE Ailles, PM Lansdorp, HJ Sutherland
Blood, The Journal of the American Society of Hematology 89 (9), 3104-3112, 1997
The cancer stem cell hypothesis: a work in progress
BT Tan, CY Park, LE Ailles, IL Weissman
Laboratory investigation 86 (12), 1203-1207, 2006
Tumor-initiating cells are rare in many human tumors
K Ishizawa, ZA Rasheed, R Karisch, Q Wang, J Kowalski, E Susky, ...
Cell stem cell 7 (3), 279-282, 2010
Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
JM Stewart, PA Shaw, C Gedye, MQ Bernardini, BG Neel, LE Ailles
Proceedings of the National Academy of Sciences 108 (16), 6468-6473, 2011
Cancer stem cells in head and neck squamous cell cancer
MEP Prince, LE Ailles
Journal of Clinical Oncology 26 (17), 2871-2875, 2008
Developmental signaling pathways in cancer stem cells of solid tumors
C Karamboulas, L Ailles
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (2), 2481-2495, 2013
Growth characteristics of acute myelogenous leukemia progenitors that initiate malignant hematopoiesis in nonobese diabetic/severe combined immunodeficient mice
LE Ailles, B Gerhard, H Kawagoe, DE Hogge
Blood, The Journal of the American Society of Hematology 94 (5), 1761-1772, 1999
Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state
M Shimoda, S Principe, HW Jackson, V Luga, H Fang, SD Molyneux, ...
Nature cell biology 16 (9), 889-901, 2014
Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness
B Joshua, MJ Kaplan, I Doweck, R Pai, IL Weissman, ME Prince, LE Ailles
Head & neck 34 (1), 42-49, 2012
Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas
S Papillon-Cavanagh, C Lu, T Gayden, LG Mikael, D Bechet, ...
Nature genetics 49 (2), 180-185, 2017
Robust and efficient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors
E Vigna, S Cavalieri, L Ailles, M Geuna, R Loew, H Bujard, L Naldini
Molecular therapy 5 (3), 252-261, 2002
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