| A role for Wnt signalling in self-renewal of haematopoietic stem cells T Reya, AW Duncan, L Ailles, J Domen, DC Scherer, K Willert, L Hintz, ... Nature 423 (6938), 409-414, 2003 | 2555 | 2003 |
| Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma ME Prince, R Sivanandan, A Kaczorowski, GT Wolf, MJ Kaplan, P Dalerba, ... Proceedings of the National Academy of Sciences 104 (3), 973-978, 2007 | 2365 | 2007 |
| Association of reactive oxygen species levels and radioresistance in cancer stem cells M Diehn, RW Cho, NA Lobo, T Kalisky, MJ Dorie, AN Kulp, D Qian, ... nature 458 (7239), 780-783, 2009 | 2159 | 2009 |
| Granulocyte–macrophage progenitors as candidate leukemic stem cells in blast-crisis CML CHM Jamieson, LE Ailles, SJ Dylla, M Muijtjens, C Jones, JL Zehnder, ... New England Journal of Medicine 351 (7), 657-667, 2004 | 1712 | 2004 |
| Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences A Follenzi, LE Ailles, S Bakovic, M Geuna, L Naldini Nature genetics 25 (2), 217-222, 2000 | 1239 | 2000 |
| Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? E Passegué, CHM Jamieson, LE Ailles, IL Weissman Proceedings of the National Academy of Sciences 100 (suppl 1), 11842-11849, 2003 | 910 | 2003 |
| Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells KS Chan, I Espinosa, M Chao, D Wong, L Ailles, M Diehn, H Gill, J Presti, ... Proceedings of the National Academy of Sciences 106 (33), 14016-14021, 2009 | 615 | 2009 |
| Cancer stem cells in solid tumors LE Ailles, IL Weissman Current opinion in biotechnology 18 (5), 460-466, 2007 | 578 | 2007 |
| Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo A Blair, DE Hogge, LE Ailles, PM Lansdorp, HJ Sutherland Blood, The Journal of the American Society of Hematology 89 (9), 3104-3112, 1997 | 445 | 1997 |
| An immune atlas of clear cell renal cell carcinoma S Chevrier, JH Levine, VRT Zanotelli, K Silina, D Schulz, M Bacac, ... Cell 169 (4), 736-749. e18, 2017 | 414 | 2017 |
| The cancer stem cell hypothesis: a work in progress BT Tan, CY Park, LE Ailles, IL Weissman Laboratory investigation 86 (12), 1203-1207, 2006 | 368 | 2006 |
| Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells JM Stewart, PA Shaw, C Gedye, MQ Bernardini, BG Neel, LE Ailles Proceedings of the National Academy of Sciences 108 (16), 6468-6473, 2011 | 227 | 2011 |
| Tumor-initiating cells are rare in many human tumors K Ishizawa, ZA Rasheed, R Karisch, Q Wang, J Kowalski, E Susky, ... Cell stem cell 7 (3), 279-282, 2010 | 224 | 2010 |
| Cancer stem cells in head and neck squamous cell cancer MEP Prince, LE Ailles Journal of Clinical Oncology 26 (17), 2871-2875, 2008 | 214 | 2008 |
| Growth characteristics of acute myelogenous leukemia progenitors that initiate malignant hematopoiesis in nonobese diabetic/severe combined immunodeficient mice LE Ailles, B Gerhard, H Kawagoe, DE Hogge Blood, The Journal of the American Society of Hematology 94 (5), 1761-1772, 1999 | 187 | 1999 |
| Developmental signaling pathways in cancer stem cells of solid tumors C Karamboulas, L Ailles Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (2), 2481-2495, 2013 | 181 | 2013 |
| Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness B Joshua, MJ Kaplan, I Doweck, R Pai, IL Weissman, ME Prince, LE Ailles Head & neck 34 (1), 42-49, 2012 | 167 | 2012 |
| Robust and efficient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors E Vigna, S Cavalieri, L Ailles, M Geuna, R Loew, H Bujard, L Naldini Molecular therapy 5 (3), 252-261, 2002 | 167 | 2002 |
| Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state M Shimoda, S Principe, HW Jackson, V Luga, H Fang, SD Molyneux, ... Nature cell biology 16 (9), 889-901, 2014 | 162 | 2014 |
| Molecular evidence of lentiviral vector-mediated gene transfer into human self-renewing, multi-potent, long-term NOD/SCID repopulating hematopoietic cells L Ailles, M Schmidt, FRS De Sio, H Glimm, S Cavalieri, S Bruno, ... Molecular Therapy 6 (5), 615-626, 2002 | 113 | 2002 |
