Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion R Zang, JB Case, E Yutuc, X Ma, S Shen, MF Gomez Castro, Z Liu, ... Proceedings of the National Academy of Sciences 117 (50), 32105-32113, 2020 | 198 | 2020 |
Defective cholesterol metabolism in amyotrophic lateral sclerosis J Abdel-Khalik, E Yutuc, PJ Crick, JÅ Gustafsson, M Warner, G Roman, ... Journal of lipid research 58 (1), 267-278, 2017 | 136 | 2017 |
New methods for analysis of oxysterols and related compounds by LC–MS WJ Griffiths, J Abdel-Khalik, PJ Crick, E Yutuc, Y Wang The Journal of steroid biochemistry and molecular biology 162, 4-26, 2016 | 80 | 2016 |
Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism E Yutuc, R Angelini, M Baumert, N Mast, I Pikuleva, J Newton, MR Clench, ... Proceedings of the National Academy of Sciences 117 (11), 5749-5760, 2020 | 57 | 2020 |
Current trends in oxysterol research WJ Griffiths, J Abdel-Khalik, T Hearn, E Yutuc, AH Morgan, Y Wang Biochemical Society Transactions 44 (2), 652-658, 2016 | 56 | 2016 |
Cholesterolomics: an update WJ Griffiths, J Abdel-Khalik, E Yutuc, AH Morgan, I Gilmore, T Hearn, ... Analytical biochemistry 524, 56-67, 2017 | 53 | 2017 |
Metabolism of non-enzymatically derived oxysterols: clues from sterol metabolic disorders WJ Griffiths, E Yutuc, J Abdel-Khalik, PJ Crick, T Hearn, A Dickson, ... Free Radical Biology and Medicine 144, 124-133, 2019 | 44 | 2019 |
An interferon regulated MicroRNA provides broad cell-intrinsic antiviral immunity through multihit host-directed targeting of the sterol pathway KA Robertson, WY Hsieh, T Forster, M Blanc, H Lu, PJ Crick, E Yutuc, ... PLoS biology 14 (3), e1002364, 2016 | 44 | 2016 |
Cholesterol metabolism pathways–are the intermediates more important than the products? Y Wang, E Yutuc, WJ Griffiths The FEBS Journal 288 (12), 3727-3745, 2021 | 43 | 2021 |
Visualizing cholesterol in the brain by on-tissue derivatization and quantitative mass spectrometry imaging R Angelini, E Yutuc, MF Wyatt, J Newton, FA Yusuf, L Griffiths, BJ Cooze, ... Analytical Chemistry 93 (11), 4932-4943, 2021 | 42 | 2021 |
Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients WJ Griffiths, J Abdel-Khalik, E Yutuc, G Roman, M Warner, JÅ Gustafsson, ... Free Radical Biology and Medicine 134, 42-52, 2019 | 37 | 2019 |
Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma WJ Griffiths, PJ Crick, A Meljon, S Theofilopoulos, J Abdel-Khalik, E Yutuc, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 37 | 2019 |
24 (S), 25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo S Theofilopoulos, WAA de Oliveira, S Yang, E Yutuc, A Saeed, ... Journal of Biological Chemistry 294 (11), 4169-4176, 2019 | 33 | 2019 |
Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle NJ Hudson, A Reverter, WJ Griffiths, E Yutuc, Y Wang, A Jeanes, ... BMC genomics 21, 1-23, 2020 | 24 | 2020 |
Identification of unusual oxysterols and bile acids with 7-oxo or 3β, 5α, 6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage … WJ Griffiths, I Gilmore, E Yutuc, J Abdel-Khalik, PJ Crick, T Hearn, ... Journal of lipid research 59 (6), 1058-1070, 2018 | 24 | 2018 |
Neuro‐oxysterols and neuro‐sterols as ligands to nuclear receptors, GPCRs, ligand‐gated ion channels and other protein receptors Y Wang, E Yutuc, WJ Griffiths British Journal of Pharmacology 178 (16), 3176-3193, 2021 | 20 | 2021 |
Charge-tagging liquid chromatography–mass spectrometry methodology targeting oxysterol diastereoisomers WJ Griffiths, T Hearn, PJ Crick, J Abdel-Khalik, A Dickson, E Yutuc, ... Chemistry and physics of lipids 207, 69-80, 2017 | 20 | 2017 |
Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis P Höflinger, S Hauser, E Yutuc, H Hengel, L Griffiths, F Radelfahr, ... Journal of lipid research 62, 2021 | 19 | 2021 |
Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry E Yutuc, AL Dickson, M Pacciarini, L Griffiths, PRS Baker, L Connell, ... Analytica Chimica Acta 1154, 338259, 2021 | 18 | 2021 |
Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates J Abdel-Khalik, T Hearn, AL Dickson, PJ Crick, E Yutuc, K Austin-Muttitt, ... The Journal of steroid biochemistry and molecular biology 206, 105794, 2021 | 17 | 2021 |