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Rune Busk Damgaard
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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin
K Keusekotten, PR Elliott, L Glockner, BK Fiil, RB Damgaard, Y Kulathu, ...
Cell 153 (6), 1312-1326, 2013
4712013
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity
RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ...
Molecular cell 46 (6), 746-758, 2012
4032012
The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity
RB Damgaard, JA Walker, P Marco-Casanova, NV Morgan, ...
Cell 166 (5), 1215-1230. e20, 2016
2932016
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling
BK Fiil, RB Damgaard, SA Wagner, K Keusekotten, M Fritsch, ...
Molecular cell 50 (6), 818-830, 2013
2652013
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation
M Yabal, N Müller, H Adler, N Knies, CJ Groß, RB Damgaard, ...
Cell reports 7 (6), 1796-1808, 2014
2582014
X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
C Speckmann, K Lehmberg, MH Albert, RB Damgaard, M Fritsch, ...
Clinical immunology 149 (1), 133-141, 2013
1822013
CYLD limits Lys63-and Met1-linked ubiquitin at receptor complexes to regulate innate immune signaling
M Hrdinka, BK Fiil, M Zucca, D Leske, K Bagola, M Yabal, PR Elliott, ...
Cell reports 14 (12), 2846-2858, 2016
1532016
Disease‐causing mutations in the XIAP BIR 2 domain impair NOD 2‐dependent immune signalling
RB Damgaard, BK Fiil, C Speckmann, M Yabal, U Stadt, S Bekker‐Jensen, ...
EMBO molecular medicine 5 (8), 1278-1295, 2013
1502013
Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity
RB Damgaard, M Gyrd-Hansen
Discovery medicine 11 (58), 221-231, 2011
992011
The ubiquitin system: from cell signalling to disease biology and new therapeutic opportunities
RB Damgaard
Cell Death & Differentiation 28 (2), 423-426, 2021
932021
OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death
RB Damgaard, PR Elliott, KN Swatek, ER Maher, P Stepensky, O Elpeleg, ...
EMBO molecular medicine 11 (3), e9324, 2019
892019
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ...
Cell Death & Differentiation 30 (5), 1097-1154, 2023
772023
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer
RB Damgaard, HE Jolin, MED Allison, SE Davies, HL Titheradge, ...
Cell Death & Differentiation 27 (5), 1457-1474, 2020
522020
Met1-linked ubiquitin signalling in health and disease: inflammation, immunity, cancer, and beyond
AS Jahan, CR Elbæk, RB Damgaard
Cell Death & Differentiation 28 (2), 473-492, 2021
412021
WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
CR Elbæk, V Petrosius, J Benada, L Erichsen, RB Damgaard, ...
Cell reports 38 (3), 2022
272022
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
L Merklinger, J Bauer, PA Pedersen, RB Damgaard, JP Morth
Life Science Alliance 5 (8), 2022
62022
Ester‐linked ubiquitination by HOIL‐1 controls immune signalling by shaping the linear ubiquitin landscape
JN Pruneda, RB Damgaard
The FEBS Journal 288 (20), 5903-5908, 2021
62021
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
N Furthmann, V Bader, L Angersbach, A Blusch, S Goel, ...
Nature Communications 14 (1), 8368, 2023
3*2023
Legionella dismantles linear ubiquitin
RB Damgaard, JN Pruneda
Nature Microbiology 4 (8), 1244-1245, 2019
22019
Universiteterne har brug for en reformpause
K Kropp, K Vallgårda, AH Laustsen-Kiel, N Albrechtsen, L Sylow, ...
Berlingske Tidende, 2023
2023
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