Jörg Menche
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A proteome-scale map of the human interactome network
T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ...
Cell 159 (5), 1212-1226, 2014
Uncovering disease-disease relationships through the incomplete interactome
J Menche, A Sharma, M Kitsak, SD Ghiassian, M Vidal, J Loscalzo, ...
Science 347 (6224), 1257601, 2015
Human symptoms–disease network
XZ Zhou, J Menche, AL Barabási, A Sharma
Nature communications 5 (1), 4212, 2014
Canonical Genetic Signatures of the Adult Human Brain
M Hawrylycz, JA Miller, V Menon, D Feng, T Dolbeare, ...
Nature Neuroscience, 2015
Network-based in silico drug efficacy screening
E Guney, J Menche, M Vidal, AL Barábasi
Nature communications 7 (1), 10331, 2016
A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome
SD Ghiassian, J Menche, AL Barabási
PLoS computational biology 11 (4), e1004120, 2015
Assessment of network module identification across complex diseases
S Choobdar, ME Ahsen, J Crawford, M Tomasoni, T Fang, D Lamparter, ...
Nature methods 16 (9), 843-852, 2019
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ...
Human molecular genetics 24 (11), 3005-3020, 2015
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers
S Schick, AF Rendeiro, K Runggatscher, A Ringler, B Boidol, M Hinkel, ...
Nature genetics 51 (9), 1399-1410, 2019
Interactome-based approaches to human disease
M Caldera, P Buphamalai, F Müller, J Menche
Current Opinion in Systems Biology 3, 88-94, 2017
Tissue specificity of human disease module
M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ...
Scientific reports 6 (1), 35241, 2016
Endophenotype network models: common core of complex diseases
SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, ...
Scientific reports 6 (1), 27414, 2016
Plasticity of the Cullin-RING ligase repertoire shapes sensitivity to ligand-induced protein degradation
C Mayor-Ruiz, MG Jaeger, S Bauer, M Brand, C Sin, A Hanzl, AC Mueller, ...
Molecular cell 75 (4), 849-858. e8, 2019
Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function
A Lercher, A Bhattacharya, AM Popa, M Caldera, MF Schlapansky, ...
Immunity 51 (6), 1074-1087. e9, 2019
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation
S Sdelci, AF Rendeiro, P Rathert, W You, JMG Lin, A Ringler, G Hofstätter, ...
Nature genetics 51 (6), 990-998, 2019
Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms
F Schischlik, R Jäger, F Rosebrock, E Hug, M Schuster, R Holly, E Fuchs, ...
Blood, The Journal of the American Society of Hematology 134 (2), 199-210, 2019
Integrating personalized gene expression profiles into predictive disease-associated gene pools
J Menche, E Guney, A Sharma, PJ Branigan, MJ Loza, F Baribaud, ...
NPJ systems biology and applications 3 (1), 10, 2017
Non-classical monocytes as mediators of tissue destruction in arthritis
A Puchner, V Saferding, M Bonelli, Y Mikami, M Hofmann, JS Brunner, ...
Annals of the rheumatic diseases 77 (10), 1490-1497, 2018
Asymptotic properties of degree-correlated scale-free networks
J Menche, A Valleriani, R Lipowsky
Physical review E 81 (4), 046103, 2010
B cell–activating factor neutralization aggravates atherosclerosis
D Tsiantoulas, AP Sage, L Göderle, M Ozsvar-Kozma, D Murphy, ...
Circulation 138 (20), 2263-2273, 2018
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