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Jacob Corn
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ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules
A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ...
Methods in enzymology 487, 545-574, 2011
17382011
Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
CD Richardson, GJ Ray, MA DeWitt, GL Curie, JE Corn
Nature biotechnology 34 (3), 339-344, 2016
10312016
A prudent path forward for genomic engineering and germline gene modification
D Baltimore, P Berg, M Botchan, D Carroll, RA Charo, G Church, JE Corn, ...
Science 348 (6230), 36-38, 2015
8482015
Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
SJ Fleishman, TA Whitehead, DC Ekiert, C Dreyfus, JE Corn, EM Strauch, ...
Science 332 (6031), 816-821, 2011
6412011
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
K Lee, M Conboy, HM Park, F Jiang, HJ Kim, MA Dewitt, VA Mackley, ...
Nature biomedical engineering 1 (11), 889-901, 2017
5662017
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ...
elife 5, e19760, 2016
5412016
RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite
SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ...
PloS one 6 (6), e20161, 2011
4752011
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells
MA DeWitt, W Magis, NL Bray, T Wang, JR Berman, F Urbinati, SJ Heo, ...
Science translational medicine 8 (360), 360ra134-360ra134, 2016
4342016
Cornerstones of CRISPR–Cas in drug discovery and therapy
C Fellmann, BG Gowen, PC Lin, JA Doudna, JE Corn
Nature reviews Drug discovery 16 (2), 89-100, 2017
3992017
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
MR Mumbach, AT Satpathy, EA Boyle, C Dai, BG Gowen, SW Cho, ...
Nature genetics 49 (11), 1602-1612, 2017
3702017
Disabling Cas9 by an anti-CRISPR DNA mimic
J Shin, F Jiang, JJ Liu, NL Bray, BJ Rauch, SH Baik, E Nogales, ...
Science advances 3 (7), e1701620, 2017
2992017
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
B Wienert, SK Wyman, CD Richardson, CD Yeh, P Akcakaya, MJ Porritt, ...
Science 364 (6437), 286-289, 2019
2842019
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
CN Cunningham, JM Baughman, L Phu, JS Tea, C Yu, M Coons, ...
Nature cell biology 17 (2), 160-169, 2015
2642015
Advances in genome editing through control of DNA repair pathways
CD Yeh, CD Richardson, JE Corn
Nature cell biology 21 (12), 1468-1478, 2019
2372019
Discovery of stimulation-responsive immune enhancers with CRISPR activation
DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ...
Nature 549 (7670), 111-115, 2017
2332017
SLC19A1 transports immunoreactive cyclic dinucleotides
RD Luteijn, SA Zaver, BG Gowen, SK Wyman, NE Garelis, L Onia, ...
Nature 573 (7774), 434-438, 2019
1902019
A de novo protein binding pair by computational design and directed evolution
J Karanicolas, JE Corn, I Chen, LA Joachimiak, O Dym, SH Peck, ...
Molecular cell 42 (2), 250-260, 2011
1902011
CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway
CD Richardson, KR Kazane, SJ Feng, E Zelin, NL Bray, AJ Schäfer, ...
Nature genetics 50 (8), 1132-1139, 2018
1882018
CRISPR germline engineering—the community speaks
KS Bosley, M Botchan, AL Bredenoord, D Carroll, RA Charo, ...
Nature biotechnology 33 (5), 478-486, 2015
1872015
Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex
ELC Dueber, JE Corn, SD Bell, JM Berger
Science 317 (5842), 1210-1213, 2007
1582007
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