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Yuen Yi C. Tam
Yuen Yi C. Tam
Integrated Nanotherapeutics Inc.
Verified email at mail.ubc.ca
Title
Cited by
Cited by
Year
On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ...
ACS nano 12 (5), 4787-4795, 2018
3692018
Influence of polyethylene glycol lipid desorption rates on pharmacokinetics and pharmacodynamics of siRNA lipid nanoparticles
BL Mui, YK Tam, M Jayaraman, SM Ansell, X Du, YYC Tam, PJC Lin, ...
Molecular Therapy-Nucleic Acids 2, 2013
2932013
Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae
M Babu, J Vlasblom, S Pu, X Guo, C Graham, BDM Bean, HE Burston, ...
Nature 489 (7417), 585-589, 2012
2772012
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
S Chen, YYC Tam, PJC Lin, MMH Sung, YK Tam, PR Cullis
Journal of Controlled Release 235, 236-244, 2016
2672016
Microfluidic mixing: a general method for encapsulating macromolecules in lipid nanoparticle systems
AKK Leung, YYC Tam, S Chen, IM Hafez, PR Cullis
The Journal of Physical Chemistry B 119 (28), 8698-8706, 2015
2522015
Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells
G Basha, TI Novobrantseva, N Rosin, YYC Tam, IM Hafez, MK Wong, ...
Molecular Therapy 19 (12), 2186-2200, 2011
2482011
Advances in lipid nanoparticles for siRNA delivery
YYC Tam, S Chen, PR Cullis
Pharmaceutics 5 (3), 498-507, 2013
2322013
On the role of helper lipids in lipid nanoparticle formulations of siRNA
JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis
Nanoscale 11 (45), 21733-21739, 2019
2192019
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer
MS Kostelansky, C Schluter, YYC Tam, S Lee, R Ghirlando, B Beach, ...
Cell 129 (3), 485-498, 2007
2152007
Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae
YYC Tam, A Fagarasanu, M Fagarasanu, RA Rachubinski
Journal of Biological Chemistry 280 (41), 34933-34939, 2005
2112005
Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane
M Marelli, JJ Smith, S Jung, E Yi, AI Nesvizhskii, RH Christmas, ...
The Journal of cell biology 167 (6), 1099-1112, 2004
1782004
Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA
JA Kulkarni, JL Myhre, S Chen, YYC Tam, A Danescu, JM Richman, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1377-1387, 2017
1642017
Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo
JB Lee, K Zhang, YYC Tam, YK Tam, NM Belliveau, VYC Sung, PJC Lin, ...
International Journal of Cancer 131 (5), E781-E790, 2012
1612012
Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration
S Chen, YYC Tam, PJC Lin, AKK Leung, YK Tam, PR Cullis
Journal of controlled release 196, 106-112, 2014
1422014
Lipid nanoparticles for short interfering RNA delivery
AKK Leung, YYC Tam, PR Cullis
Advances in genetics 88, 71-110, 2014
1412014
Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae
M Fagarasanu, A Fagarasanu, YYC Tam, JD Aitchison, RA Rachubinski
The Journal of cell biology 169 (5), 765-775, 2005
1362005
Pex11-related Proteins in Peroxisome Dynamics: A Role for the Novel Peroxin Pex27p in Controlling Peroxisome Size and Number in Saccharomyces cerevisiae
YYC Tam, JC Torres-Guzman, FJ Vizeacoumar, JJ Smith, M Marelli, ...
Molecular biology of the cell 14 (10), 4089-4102, 2003
1312003
YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae
FJ Vizeacoumar, JC Torres-Guzman, YYC Tam, JD Aitchison, ...
The Journal of cell biology 161 (2), 321-332, 2003
1252003
Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA
PJC Lin, YYC Tam, I Hafez, A Sandhu, S Chen, MA Ciufolini, IR Nabi, ...
Nanomedicine: Nanotechnology, Biology and Medicine 9 (2), 233-246, 2013
992013
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads
JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ...
Nanoscale 11 (18), 9023-9031, 2019
962019
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