| Architecture of the human interactome defines protein communities and disease networks EL Huttlin, RJ Bruckner, JA Paulo, JR Cannon, L Ting, K Baltier, G Colby, ... Nature 545 (7655), 505-509, 2017 | 1356 | 2017 |
| Quantitative proteomics of the cancer cell line encyclopedia DP Nusinow, J Szpyt, M Ghandi, CM Rose, ER McDonald III, M Kalocsay, ... Cell 180 (2), 387-402. e16, 2020 | 660 | 2020 |
| Dual proteome-scale networks reveal cell-specific remodeling of the human interactome EL Huttlin, RJ Bruckner, J Navarrete-Perea, JR Cannon, K Baltier, ... Cell 184 (11), 3022-3040. e28, 2021 | 562 | 2021 |
| Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells AN Kettenbach, DK Schweppe, BK Faherty, D Pechenick, AA Pletnev, ... Science signaling 4 (179), rs5-rs5, 2011 | 544 | 2011 |
| TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples J Li, JG Van Vranken, L Pontano Vaites, DK Schweppe, EL Huttlin, ... Nature methods 17 (4), 399-404, 2020 | 344 | 2020 |
| A quantitative tissue-specific landscape of protein redox regulation during aging H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ... Cell 180 (5), 968-983. e24, 2020 | 259 | 2020 |
| Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics DK Schweppe, JK Eng, Q Yu, D Bailey, R Rad, J Navarrete-Perea, ... Journal of proteome research 19 (5), 2026-2034, 2020 | 193 | 2020 |
| Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry DK Schweppe, JD Chavez, CF Lee, A Caudal, SE Kruse, R Stuppard, ... Proceedings of the National Academy of Sciences 114 (7), 1732-1737, 2017 | 189 | 2017 |
| Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries M Kuljanin, DC Mitchell, DK Schweppe, AS Gikandi, DP Nusinow, ... Nature biotechnology 39 (5), 630-641, 2021 | 173 | 2021 |
| Characterization and optimization of multiplexed quantitative analyses using high-field asymmetric-waveform ion mobility mass spectrometry DK Schweppe, S Prasad, MW Belford, J Navarrete-Perea, DJ Bailey, ... Analytical chemistry 91 (6), 4010-4016, 2019 | 165 | 2019 |
| Host-microbe protein interactions during bacterial infection DK Schweppe, C Harding, JD Chavez, X Wu, E Ramage, PK Singh, ... Chemistry & biology 22 (11), 1521-1530, 2015 | 141 | 2015 |
| Active instrument engagement combined with a real-time database search for improved performance of sample multiplexing workflows BK Erickson, J Mintseris, DK Schweppe, J Navarrete-Perea, AR Erickson, ... Journal of proteome research 18 (3), 1299-1306, 2019 | 110 | 2019 |
| Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors DK Schweppe, JR Rigas, SA Gerber Journal of proteomics 91, 286-296, 2013 | 110 | 2013 |
| In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075 X Wu, JD Chavez, DK Schweppe, C Zheng, CR Weisbrod, JK Eng, ... Nature communications 7 (1), 13414, 2016 | 100 | 2016 |
| Quantitative interactome analysis reveals a chemoresistant edgotype JD Chavez, DK Schweppe, JK Eng, C Zheng, A Taipale, Y Zhang, ... Nature communications 6 (1), 7928, 2015 | 93 | 2015 |
| In vivo conformational dynamics of Hsp90 and its interactors JD Chavez, DK Schweppe, JK Eng, JE Bruce Cell chemical biology 23 (6), 716-726, 2016 | 81 | 2016 |
| Sample multiplexing for targeted pathway proteomics in aging mice Q Yu, H Xiao, MP Jedrychowski, DK Schweppe, J Navarrete-Perea, ... Proceedings of the National Academy of Sciences 117 (18), 9723-9732, 2020 | 76 | 2020 |
| BioPlex display: an interactive suite for large-scale AP–MS protein–protein interaction data DK Schweppe, EL Huttlin, JW Harper, SP Gygi Journal of proteome research 17 (1), 722-726, 2018 | 72 | 2018 |
| Optimized workflow for multiplexed phosphorylation analysis of TMT-labeled peptides using high-field asymmetric waveform ion mobility spectrometry DK Schweppe, SF Rusin, SP Gygi, JA Paulo Journal of proteome research 19 (1), 554-560, 2019 | 61 | 2019 |
| A general method for targeted quantitative cross-linking mass spectrometry JD Chavez, JK Eng, DK Schweppe, M Cilia, K Rivera, X Zhong, X Wu, ... PLoS One 11 (12), e0167547, 2016 | 59 | 2016 |
Steven GygiProfessor of Cell Biology, Harvard Medical SchoolVerified email at hms.harvard.edu
