Hughes, Christopher S.
Hughes, Christopher S.
Group Leader, Proteomics, BC Cancer Agency
Verified email at
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Matrigel: a complex protein mixture required for optimal growth of cell culture
CS Hughes, LM Postovit, GA Lajoie
Proteomics 10 (9), 1886-1890, 2010
Ultrasensitive proteome analysis using paramagnetic bead technology
CS Hughes, S Foehr, DA Garfield, EE Furlong, LM Steinmetz, J Krijgsveld
Molecular systems biology 10 (10), 757, 2014
Prevention of amino acid conversion in SILAC experiments with embryonic stem cells
SC Bendall, C Hughes, MH Stewart, B Doble, M Bhatia, GA Lajoie
Molecular & Cellular Proteomics 7 (9), 1587-1597, 2008
Single-pot, solid-phase-enhanced sample preparation for proteomics experiments
CS Hughes, S Moggridge, T Müller, PH Sorensen, GB Morin, J Krijgsveld
Nature protocols 14 (1), 68-85, 2019
High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry
J Wu, CS Hughes, P Picard, S Letarte, M Gaudreault, JF Lévesque, ...
Analytical Chemistry 79 (12), 4657-4665, 2007
Streptavidin paramagnetic particles provide a choice of three affinity-based capture and magnetic concentration strategies for retroviral vectors
C Hughes, J Galea-Lauri, F Farzaneh, D Darling
Molecular Therapy 3 (4), 623-630, 2001
Identification of maturation-specific proteins by single-cell proteomics of human oocytes
I Virant-Klun, S Leicht, C Hughes, J Krijgsveld
Molecular & Cellular Proteomics 15 (8), 2616-2627, 2016
An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture
SC Bendall, C Hughes, JL Campbell, MH Stewart, P Pittock, S Liu, ...
Molecular & Cellular Proteomics 8 (3), 421-432, 2009
Extending the compatibility of the SP3 paramagnetic bead processing approach for proteomics
S Moggridge, PH Sorensen, GB Morin, CS Hughes
Journal of proteome research 17 (4), 1730-1740, 2018
CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion
JF Tien, A Mazloomian, SWG Cheng, CS Hughes, CCT Chow, LT Canapi, ...
Nucleic acids research 45 (11), 6698-6716, 2017
De novo sequencing methods in proteomics
C Hughes, B Ma, GA Lajoie
Proteome Bioinformatics, 105-121, 2010
Quantitative profiling of single formalin fixed tumour sections: proteomics for translational research
CS Hughes, MK McConechy, DR Cochrane, T Nazeran, AN Karnezis, ...
Scientific reports 6 (1), 1-14, 2016
Teaching grammar, structure and meaning: exploring theory and practice for post-16 English Language teachers
M Giovanelli
Routledge, 2014
Proteomic analysis of extracellular matrices used in stem cell culture
CS Hughes, L Radan, D Betts, LM Postovit, GA Lajoie
Proteomics 11 (20), 3983-3991, 2011
Mass spectrometry–based proteomic analysis of the matrix microenvironment in pluripotent stem cell culture
C Hughes, L Radan, WY Chang, WL Stanford, DH Betts, LM Postovit, ...
Molecular & Cellular Proteomics 11 (12), 1924-1936, 2012
Fusagene vectors: a novel strategy for the expression of multiple genes from a single cistron
J Gäken, J Jiang, K Daniel, E Van Berkel, C Hughes, M Kuiper, D Darling, ...
Gene therapy 7 (23), 1979-1985, 2000
Human fibroblast matrices bio‐assembled under macromolecular crowding support stable propagation of human embryonic stem cells
Y Peng, MT Bocker, J Holm, WS Toh, CS Hughes, F Kidwai, GA Lajoie, ...
Journal of tissue engineering and regenerative medicine 6 (10), e74-e86, 2012
Translational capacity of a cell is determined during transcription elongation via the Ccr4-Not complex
I Gupta, Z Villanyi, S Kassem, C Hughes, OO Panasenko, LM Steinmetz, ...
Cell reports 15 (8), 1782-1794, 2016
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor
T Funnell, S Tasaki, A Oloumi, S Araki, E Kong, D Yap, Y Nakayama, ...
Nature communications 8 (1), 1-16, 2017
Microenvironmental regulation of telomerase isoforms in human embryonic stem cells
L Radan, CS Hughes, JH Teichroeb, FM Vieira Zamora, M Jewer, ...
Stem cells and development 23 (17), 2046-2066, 2014
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