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John Beale
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Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins
A Ebrahim, T Moreno-Chicano, MV Appleby, AK Chaplin, JH Beale, ...
IUCrJ 6 (4), 543-551, 2019
702019
Crystal structures of the extracellular domain from PepT1 and PepT2 provide novel insights into mammalian peptide transport
JH Beale, JL Parker, F Samsudin, AL Barrett, A Senan, LE Bird, D Scott, ...
Structure 23 (10), 1889-1899, 2015
542015
Successful sample preparation for serial crystallography experiments
JH Beale, R Bolton, SA Marshall, EV Beale, SB Carr, A Ebrahim, ...
Journal of applied crystallography 52 (6), 1385-1396, 2019
462019
High-throughput structures of protein–ligand complexes at room temperature using serial femtosecond crystallography
T Moreno-Chicano, A Ebrahim, D Axford, MV Appleby, JH Beale, ...
IUCrJ 6 (6), 1074-1085, 2019
412019
Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography
A Ebrahim, MV Appleby, D Axford, J Beale, T Moreno-Chicano, ...
Acta Crystallographica Section D: Structural Biology 75 (2), 151-159, 2019
382019
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
A Butryn, PS Simon, P Aller, P Hinchliffe, RN Massad, G Leen, CL Tooke, ...
Nature communications 12 (1), 4461, 2021
372021
X-ray–induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner
V Pfanzagl, JH Beale, H Michlits, D Schmidt, T Gabler, C Obinger, ...
Journal of Biological Chemistry 295 (39), 13488-13501, 2020
372020
Reducing sample consumption for serial crystallography using acoustic drop ejection
B Davy, D Axford, JH Beale, A Butryn, P Docker, A Ebrahim, G Leen, ...
Journal of synchrotron radiation 26 (5), 1820-1825, 2019
252019
Non-contact universal sample presentation for room temperature macromolecular crystallography using acoustic levitation
RH Morris, ER Dye, D Axford, MI Newton, JH Beale, PT Docker
Scientific reports 9 (1), 12431, 2019
182019
How best to use photons
G Winter, RJ Gildea, NG Paterson, J Beale, M Gerstel, D Axford, ...
Acta Crystallographica Section D: Structural Biology 75 (3), 242-261, 2019
162019
Anaerobic fixed-target serial crystallography
P Rabe, JH Beale, A Butryn, P Aller, A Dirr, PA Lang, DN Axford, SB Carr, ...
IUCrJ 7 (5), 901-912, 2020
142020
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography
M Wranik, T Weinert, C Slavov, T Masini, A Furrer, N Gaillard, D Gioia, ...
Nature Communications 14 (1), 903, 2023
132023
Structure of the aliphatic sulfonate-binding protein SsuA from Escherichia coli
J Beale, SY Lee, S Iwata, K Beis
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
102010
Probing ligand binding of endothiapepsin bytemperature-resolved'macromolecular crystallography
CY Huang, S Aumonier, S Engilberge, D Eris, KML Smith, F Leonarski, ...
Acta Crystallographica Section D: Structural Biology 78 (8), 964-974, 2022
82022
Time-resolved crystallography captures light-driven DNA repair
NE Christou, V Apostolopoulou, DVM Melo, M Ruppert, A Fadini, ...
Science 382 (6674), 1015-1020, 2023
72023
Versatile microporous polymer-based supports for serial macromolecular crystallography
I Martiel, JH Beale, A Karpik, CY Huang, L Vera, N Olieric, M Wranik, ...
Acta Crystallographica Section D: Structural Biology 77 (9), 1153-1167, 2021
72021
Macromolecular X-ray crystallography: soon to be a road less travelled?
JH Beale
Acta Crystallographica Section D: Structural Biology 76 (5), 400-405, 2020
52020
Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature
T Moreno-Chicano, LM Carey, D Axford, JH Beale, RB Doak, ...
IUCrJ 9 (5), 610-624, 2022
42022
Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs
M Carrillo, TJ Mason, A Karpik, I Martiel, MW Kepa, KE McAuley, JH Beale, ...
IUCrJ 10 (6), 2023
12023
A standard descriptor for fixed-target serial crystallography
RL Owen, D de Sanctis, AR Pearson, JH Beale
Acta Crystallographica Section D: Structural Biology 79 (8), 2023
2023
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