Getting TRAIL back on track for cancer therapy JV Lemke, S von Karstedt, J Zinngrebe, H Walczak Cell Death & Differentiation 21 (9), 1350-1364, 2014 | 540 | 2014 |
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy S Von Karstedt, A Montinaro, H Walczak Nature Reviews Cancer 17 (6), 352-366, 2017 | 531 | 2017 |
Ferroptosis in cancer cell biology CM Bebber, F Müller, L Prieto Clemente, J Weber, S von Karstedt Cancers 12 (1), 164, 2020 | 255 | 2020 |
Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance JKM Lim, A Delaidelli, SW Minaker, HF Zhang, M Colovic, H Yang, ... Proceedings of the National Academy of Sciences 116 (19), 9433-9442, 2019 | 229 | 2019 |
The TRAIL-induced cancer secretome promotes a tumor-supportive immune microenvironment via CCR2 T Hartwig, A Montinaro, S von Karstedt, A Sevko, S Surinova, ... Molecular cell 65 (4), 730-742. e5, 2017 | 214 | 2017 |
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis S von Karstedt, A Conti, M Nobis, A Montinaro, T Hartwig, J Lemke, ... Cancer cell 27 (4), 561-573, 2015 | 193 | 2015 |
Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics L Pedrera, RA Espiritu, U Ros, J Weber, A Schmitt, J Stroh, S Hailfinger, ... Cell Death & Differentiation 28 (5), 1644-1657, 2021 | 185 | 2021 |
Is TRAIL the holy grail of cancer therapy? T Newsom-Davis, S Prieske, H Walczak Apoptosis 14, 607-623, 2009 | 173 | 2009 |
Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1 J Lemke, S von Karstedt, M Abd El Hay, A Conti, F Arce, A Montinaro, ... Cell Death & Differentiation 21 (3), 491-502, 2014 | 137 | 2014 |
The emerging role of cyclin-dependent kinases (CDKs) in pancreatic ductal adenocarcinoma B García-Reyes, AL Kretz, JP Ruff, S Von Karstedt, A Hillenbrand, ... International journal of molecular sciences 19 (10), 3219, 2018 | 95 | 2018 |
Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023 | 93 | 2023 |
TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells MH Tuthill, A Montinaro, J Zinngrebe, K Prieske, P Draber, S Prieske, ... Oncogene 34 (16), 2138-2144, 2015 | 92 | 2015 |
Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes CM Bebber, ES Thomas, J Stroh, Z Chen, A Androulidaki, A Schmitt, ... Nature communications 12 (1), 2048, 2021 | 89 | 2021 |
Friend or foe: S100 proteins in cancer C Allgöwer, AL Kretz, S von Karstedt, M Wittau, D Henne-Bruns, J Lemke Cancers 12 (8), 2037, 2020 | 81 | 2020 |
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation J Zinngrebe, E Rieser, L Taraborrelli, N Peltzer, T Hartwig, H Ren, ... Journal of Experimental Medicine 213 (12), 2671-2689, 2016 | 80 | 2016 |
TRAILblazing strategies for cancer treatment AL Kretz, A Trauzold, A Hillenbrand, U Knippschild, D Henne-Bruns, ... Cancers 11 (4), 456, 2019 | 74 | 2019 |
Should we keep walking along the trail for pancreatic cancer treatment? Revisiting TNF-related apoptosis-inducing ligand for anticancer therapy AL Kretz, S Von Karstedt, A Hillenbrand, D Henne-Bruns, U Knippschild, ... Cancers 10 (3), 77, 2018 | 56 | 2018 |
Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation F Müller, JKM Lim, CM Bebber, E Seidel, S Tishina, A Dahlhaus, J Stroh, ... Cell Death & Differentiation 30 (2), 442-456, 2023 | 45 | 2023 |
Dynasore blocks ferroptosis through combined modulation of iron uptake and inhibition of mitochondrial respiration LP Clemente, M Rabenau, S Tang, J Stanka, E Cors, J Stroh, C Culmsee, ... Cells 9 (10), 2259, 2020 | 39 | 2020 |
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I J Brägelmann, C Lorenz, S Borchmann, K Nishii, J Wegner, L Meder, ... Nature communications 12 (1), 5505, 2021 | 38 | 2021 |