Inducible activation of CEBPB, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells C Guerzoni, M Bardini, SA Mariani, G Ferrari-Amorotti, P Neviani, ... Blood 107 (10), 4080-4089, 2006 | 117 | 2006 |
Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis A Agraz-Doblas, C Bueno, R Bashford-Rogers, A Roy, P Schneider, ... haematologica 104 (6), 1176, 2019 | 88 | 2019 |
Bortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouse VA Carozzi, CL Renn, M Bardini, G Fazio, A Chiorazzi, C Meregalli, ... PloS one 8 (9), e72995, 2013 | 82 | 2013 |
DNA copy-number abnormalities do not occur in infant ALL with t (4; 11)/MLL-AF4 M Bardini, R Spinelli, S Bungaro, E Mangano, L Corral, I Cifola, G Fazio, ... Leukemia 24 (1), 169-176, 2010 | 76 | 2010 |
The silent mutational landscape of infant MLL‐AF4 pro‐B acute lymphoblastic leukemia SE Dobbins, AL Sherborne, YP Ma, M Bardini, A Biondi, G Cazzaniga, ... Genes, Chromosomes and Cancer 52 (10), 954-960, 2013 | 69 | 2013 |
Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement M Bardini, PS Woll, L Corral, S Luc, L Wittmann, Z Ma, L Lo Nigro, ... Leukemia 29 (1), 38-50, 2015 | 58 | 2015 |
Implementation of array based whole-genome high-resolution technologies confirms the absence of secondary copy-number alterations in MLL-AF4-positive infant ALL patients M Bardini, M Galbiati, A Lettieri, S Bungaro, TA Gorletta, A Biondi, ... Leukemia 25 (1), 175-178, 2011 | 52 | 2011 |
Development refractoriness of MLL-rearranged human B cell acute leukemias to reprogramming into pluripotency A Muñoz-López, D Romero-Moya, C Prieto, V Ramos-Mejía, ... Stem cell reports 7 (4), 602-618, 2016 | 50 | 2016 |
The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL AM Savino, J Sarno, L Trentin, M Vieri, G Fazio, M Bardini, C Bugarin, ... Leukemia 31 (11), 2365-2375, 2017 | 45 | 2017 |
NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL C Prieto, B López-Millán, H Roca-Ho, RW Stam, D Romero-Moya, ... Leukemia 32 (3), 633-644, 2018 | 41 | 2018 |
Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase AM Savino, SI Fernandes, O Olivares, A Zemlyansky, A Cousins, ... Nature cancer 1 (10), 998-1009, 2020 | 39 | 2020 |
Preclinical efficacy and safety of CD19CAR cytokine-induced killer cells transfected with sleeping beauty transposon for the treatment of acute lymphoblastic leukemia CF Magnani, C Mezzanotte, C Cappuzzello, M Bardini, S Tettamanti, ... Human gene therapy 29 (5), 602-613, 2018 | 39 | 2018 |
Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis L Trentin, S Bresolin, E Giarin, M Bardini, V Serafin, B Accordi, F Fais, ... Scientific reports 6 (1), 34449, 2016 | 26 | 2016 |
Minimal residual disease in BCR:: ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease J Zuna, L Hovorkova, J Krotka, A Koehrmann, M Bardini, L Winkowska, ... Leukemia 36 (12), 2793-2801, 2022 | 23 | 2022 |
LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients V Cazzaniga, C Bugarin, M Bardini, M Giordan, G te Kronnie, G Basso, ... Oncotarget 6 (3), 1569, 2015 | 22 | 2015 |
Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4+ Infant ALL M Bardini, L Trentin, F Rizzo, M Vieri, AM Savino, P Garrido Castro, ... Molecular Cancer Therapeutics 17 (8), 1705-1716, 2018 | 20 | 2018 |
Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia JR Tejedor, C Bueno, M Vinyoles, P Petazzi, A Agraz-Doblas, I Cobo, ... The Journal of Clinical Investigation 131 (13), 2021 | 14 | 2021 |
Recurrent genetic fusions redefine MLL germ line acute lymphoblastic leukemia in infants G Fazio, M Bardini, P De Lorenzo, A Grioni, M Quadri, L Pedace, ... Blood, The Journal of the American Society of Hematology 137 (14), 1980-1984, 2021 | 14 | 2021 |
Expression of CCL9/MIP-1γ is repressed by BCR/ABL and its restoration suppresses in vivo leukemogenesis of 32D-BCR/ABL cells G Iotti, G Ferrari-Amorotti, C Rosafio, F Corradini, MR Lidonnici, ... Oncogene 26 (24), 3482-3491, 2007 | 14 | 2007 |
PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120 G Fazio, S Bresolin, D Silvestri, M Quadri, C Saitta, E Vendramini, ... EBioMedicine 83, 2022 | 9 | 2022 |