Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy F Li, G Sethi Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1805 (2), 167-180, 2010 | 510 | 2010 |
Potential role of signal transducer and activator of transcription (STAT) 3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma A Subramaniam, MK Shanmugam, E Perumal, F Li, A Nachiyappan, X Dai, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (1), 46-60, 2013 | 347 | 2013 |
Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells F Li, PP Fernandez, P Rajendran, KM Hui, G Sethi Cancer letters 292 (2), 197-207, 2010 | 221 | 2010 |
Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription … F Li, P Rajendran, G Sethi British journal of pharmacology 161 (3), 541-554, 2010 | 211 | 2010 |
NF-κB in cancer therapy F Li, J Zhang, F Arfuso, A Chinnathambi, ME Zayed, SA Alharbi, ... Archives of toxicology 89, 711-731, 2015 | 202 | 2015 |
A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value C Zou, A Chen, L Xiao, HM Muller, P Ache, G Haberer, M Zhang, W Jia, ... Cell Research 27 (11), 1327-1340, 2017 | 192 | 2017 |
Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma F Li, MK Shanmugam, L Chen, S Chatterjee, J Basha, AP Kumar, ... Cancer prevention research 6 (8), 843-854, 2013 | 185 | 2013 |
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways R Kannaiyan, KA Manu, L Chen, F Li, P Rajendran, A Subramaniam, ... Apoptosis 16, 1028-1041, 2011 | 176 | 2011 |
Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo G Sethi, S Chatterjee, P Rajendran, F Li, MK Shanmugam, KF Wong, ... Molecular cancer 13, 1-14, 2014 | 172 | 2014 |
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo P Rajendran, F Li, MK Shanmugam, R Kannaiyan, JN Goh, KF Wong, ... Cancer prevention research 5 (4), 631-643, 2012 | 172 | 2012 |
Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice MK Shanmugam, P Rajendran, F Li, T Nema, S Vali, T Abbasi, S Kapoor, ... Journal of molecular medicine 89, 713-727, 2011 | 170 | 2011 |
Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo CD Mohan, H Bharathkumar, KC Bulusu, V Pandey, S Rangappa, ... Journal of Biological Chemistry 289 (49), 34296-34307, 2014 | 162 | 2014 |
Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer KA Manu, MK Shanmugam, L Ramachandran, F Li, KS Siveen, ... Cancer Letters 363 (1), 28-36, 2015 | 158 | 2015 |
Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse … KS Siveen, N Mustafa, F Li, R Kannaiyan, KS Ahn, AP Kumar, WJ Chng, ... Oncotarget 5 (3), 634, 2014 | 156 | 2014 |
First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB … KA Manu, MK Shanmugam, L Ramachandran, F Li, CW Fong, AP Kumar, ... Clinical Cancer Research 18 (8), 2220-2229, 2012 | 155 | 2012 |
γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model KS Siveen, KS Ahn, TH Ong, MK Shanmugam, F Li, WN Yap, AP Kumar, ... Oncotarget 5 (7), 1897, 2014 | 152 | 2014 |
Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products KA Manu, MK Shanmugam, F Li, L Chen, KS Siveen, KS Ahn, AP Kumar, ... Journal of molecular medicine 92, 267-276, 2014 | 151 | 2014 |
Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ... Journal of Biological Chemistry 287 (45), 38028-38040, 2012 | 151 | 2012 |
Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3 A Subramaniam, MK Shanmugam, TH Ong, F Li, E Perumal, L Chen, ... British journal of pharmacology 170 (4), 807-821, 2013 | 150 | 2013 |
Honokiol inhibits signal transducer and activator of transcription‐3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine … P Rajendran, F Li, MK Shanmugam, S Vali, T Abbasi, S Kapoor, KS Ahn, ... Journal of cellular physiology 227 (5), 2184-2195, 2012 | 149 | 2012 |