| General methods for analysis of sequential “n-step” kinetic mechanisms: application to single turnover kinetics of helicase-catalyzed DNA unwinding AL Lucius, NK Maluf, CJ Fischer, TM Lohman Biophysical journal 85 (4), 2224-2239, 2003 | 165 | 2003 |
| DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies AL Lucius, A Vindigni, R Gregorian, JA Ali, AF Taylor, GR Smith, ... Journal of molecular biology 324 (3), 409-428, 2002 | 101 | 2002 |
| Fluorescence stopped-flow studies of single turnover kinetics of E. coli RecBCD helicase-catalyzed DNA unwinding AL Lucius, CJ Wong, TM Lohman Journal of molecular biology 339 (4), 731-750, 2004 | 92 | 2004 |
| Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A BC Chenna, BA Shinkre, JR King, AL Lucius, SVL Narayana, SE Velu Bioorganic & medicinal chemistry letters 18 (1), 380-385, 2008 | 65 | 2008 |
| Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis KE Lopez, AN Rizo, E Tse, JB Lin, NW Scull, AC Thwin, AL Lucius, ... Nature structural & molecular biology 27 (5), 406-416, 2020 | 57 | 2020 |
| Effects of temperature and ATP on the kinetic mechanism and kinetic step-size for E. coli RecBCD helicase-catalyzed DNA unwinding AL Lucius, TM Lohman Journal of molecular biology 339 (4), 751-771, 2004 | 53 | 2004 |
| E. coli ClpA catalyzed polypeptide translocation is allosterically controlled by the protease ClpP JM Miller, J Lin, T Li, AL Lucius Journal of molecular biology 425 (15), 2795-2812, 2013 | 47 | 2013 |
| Escherichia coli ClpB is a non-processive polypeptide translocase T Li, CL Weaver, J Lin, EC Duran, JM Miller, AL Lucius Biochemical Journal 470 (1), 39-52, 2015 | 46 | 2015 |
| Molecular mechanism of polypeptide translocation catalyzed by the Escherichia coli ClpA protein translocase B Rajendar, AL Lucius Journal of molecular biology 399 (5), 665-679, 2010 | 45 | 2010 |
| Comparative analysis of the structure and function of AAA+ motors ClpA, ClpB, and Hsp104: Common threads and disparate functions EC Duran, CL Weaver, AL Lucius Frontiers in molecular biosciences 4, 54, 2017 | 43 | 2017 |
| Energetics of DNA end binding by E. coli RecBC and RecBCD helicases indicate loop formation in the 3′-single-stranded DNA tail CJ Wong, AL Lucius, TM Lohman Journal of molecular biology 352 (4), 765-782, 2005 | 43 | 2005 |
| Transient-state kinetic analysis of the RNA polymerase I nucleotide incorporation mechanism FD Appling, AL Lucius, DA Schneider Biophysical journal 109 (11), 2382-2393, 2015 | 35 | 2015 |
| The A12. 2 subunit is an intrinsic destabilizer of the RNA polymerase I elongation complex FD Appling, CE Scull, AL Lucius, DA Schneider Biophysical journal 114 (11), 2507-2515, 2018 | 29 | 2018 |
| Multisubunit RNA polymerase cleavage factors modulate the kinetics and energetics of nucleotide incorporation: an RNA polymerase I case study FD Appling, DA Schneider, AL Lucius Biochemistry 56 (42), 5654-5662, 2017 | 29 | 2017 |
| Generally Applicable NMR Titration Methods for the Determination of Equilibrium Constants for Coordination Complexes: Syntheses and Characterizations of Metallacrown Ethers … JT Sheff, AL Lucius, SB Owens, GM Gray Organometallics 30 (21), 5695-5709, 2011 | 29 | 2011 |
| Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors BC Chenna, JR King, BA Shinkre, AL Glover, AL Lucius, SE Velu European journal of medicinal chemistry 45 (9), 3752-3761, 2010 | 29 | 2010 |
| A novel assay for RNA polymerase I transcription elongation sheds light on the evolutionary divergence of eukaryotic RNA polymerases CE Scull, ZM Ingram, AL Lucius, DA Schneider Biochemistry 58 (16), 2116-2124, 2019 | 27 | 2019 |
| The Escherichia coli ClpA Molecular Chaperone Self-Assembles into Tetramers PK Veronese, RP Stafford, AL Lucius Biochemistry 48 (39), 9221-9233, 2009 | 27 | 2009 |
| The Escherichia coli PriA helicase has two nucleotide-binding sites differing dramatically in their affinities for nucleotide cofactors. 1. Intrinsic affinities … AL Lucius, MJ Jezewska, W Bujalowski Biochemistry 45 (23), 7202-7216, 2006 | 27 | 2006 |
| Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I CE Scull, AM Clarke, AL Lucius, DA Schneider Journal of Biological Chemistry 295 (5), 1288-1299, 2020 | 26 | 2020 |
Timothy M. LohmanMarvin A. Brennecke Professor of Biophysics, Washington University in St. Louis School of MedicineVerified email at wustl.edu
