| Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3372 | 2009 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2401 | 2019 |
| Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2228 | 2011 |
| Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ... Jama 313 (19), 1924-1938, 2015 | 1587 | 2015 |
| Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1417 | 2018 |
| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1214 | 2022 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 951 | 2017 |
| Therapeutic approaches to Alzheimer's disease HW Klafki, M Staufenbiel, J Kornhuber, J Wiltfang Brain 129 (11), 2840-2855, 2006 | 481 | 2006 |
| Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ... PloS one 5 (11), e13950, 2010 | 456 | 2010 |
| BOLD fMRI deactivation of limbic and temporal brain structures and mood enhancing effect by transcutaneous vagus nerve stimulation T Kraus, K Hösl, O Kiess, A Schanze, J Kornhuber, C Forster Journal of neural transmission 114, 1485-1493, 2007 | 453 | 2007 |
| Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt–Jakob disease M Otto, J Wiltfang, H Tumani, I Zerr, M Lantsch, J Kornhuber, T Weber, ... Neuroscience letters 225 (3), 210-212, 1997 | 442 | 1997 |
| Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents—preclinical studies W Danysz, CG Parsons, J Kornhuber, WJ Schmidt, G Quack Neuroscience & Biobehavioral Reviews 21 (4), 455-468, 1997 | 442 | 1997 |
| Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs E Gulbins, M Palmada, M Reichel, A Lüth, C Böhmer, D Amato, CP Müller, ... Nature medicine 19 (7), 934-938, 2013 | 439 | 2013 |
| Neurochemical diagnosis of Alzheimer’s dementia by CSF Aβ42, Aβ42/Aβ40 ratio and total tau P Lewczuk, H Esselmann, M Otto, JM Maler, AW Henkel, MK Henkel, ... Neurobiology of aging 25 (3), 273-281, 2004 | 401 | 2004 |
| Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications J Kornhuber, P Tripal, M Reichel, C Mühle, C Rhein, M Muehlbacher, ... Cellular Physiology and Biochemistry 26 (1), 9-20, 2010 | 399 | 2010 |
| Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage SJB Vos, F Verhey, L Frölich, J Kornhuber, J Wiltfang, W Maier, O Peters, ... Brain 138 (5), 1327-1338, 2015 | 393 | 2015 |
| Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study J Kornhuber, J Bormann, M Hübers, K Rusche, P Riederer European Journal of Pharmacology: Molecular Pharmacology 206 (4), 297-300, 1991 | 391 | 1991 |
| Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic … J Wiltfang, H Esselmann, M Bibl, A Smirnov, M Otto, S Paul, B Schmidt, ... Journal of neurochemistry 81 (3), 481-496, 2002 | 370 | 2002 |
| Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia RER Slot, SAM Sikkes, J Berkhof, H Brodaty, R Buckley, E Cavedo, ... Alzheimer's & Dementia 15 (3), 465-476, 2019 | 361 | 2019 |
| Brain membrane lipids in major depression and anxiety disorders CP Müller, M Reichel, C Mühle, C Rhein, E Gulbins, J Kornhuber Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 343 | 2015 |
