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Purba Nag
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CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer
E Sanij, KM Hannan, J Xuan, S Yan, JE Ahern, AS Trigos, N Brajanovski, ...
Nature communications 11 (1), 2641, 2020
1122020
Enhanced dependency of KRAS‐mutant colorectal cancer cells on RAD 51‐dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae
M Kalimutho, AL Bain, B Mukherjee, P Nag, DM Nanayakkara, SK Harten, ...
Molecular oncology 11 (5), 470-490, 2017
372017
Cep55 overexpression promotes genomic instability and tumorigenesis in mice
D Sinha, P Nag, D Nanayakkara, PHG Duijf, A Burgess, P Raninga, ...
Communications biology 3 (1), 593, 2020
272020
Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress
W Shi, T Vu, D Boucher, A Biernacka, J Nde, RK Pandita, J Straube, ...
Blood, The Journal of the American Society of Hematology 129 (18), 2479-2492, 2017
222017
Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells
MA Khan, P Nag, A Grivei, KTK Giuliani, X Wang, V Diwan, W Hoy, ...
Cell Death & Disease 13 (2), 104, 2022
182022
Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer
M Kalimutho, D Sinha, D Mittal, S Srihari, D Nanayakkara, S Shafique, ...
Journal of Experimental & Clinical Cancer Research 38, 1-18, 2019
182019
Underlying histopathology determines response to oxidative stress in cultured human primary proximal tubular epithelial cells
MA Khan, X Wang, KTK Giuliani, P Nag, A Grivei, J Ungerer, W Hoy, ...
International Journal of Molecular Sciences 21 (2), 560, 2020
142020
Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells
KTK Giuliani, A Grivei, P Nag, X Wang, M Rist, K Kildey, B Law, MS Ng, ...
Cell Death & Disease 13 (8), 739, 2022
122022
The 2-μm plasmid encoded protein Raf1 regulates both stability and copy number of the plasmid by blocking the formation of the Rep1–Rep2 repressor complex
SM A. Rizvi, HK Prajapati, P Nag, SK Ghosh
Nucleic acids research 45 (12), 7167-7179, 2017
112017
HYPOXIA AND INTERLEUKIN (IL)-1β SYNERGISTICALLY INDUCE CELLULAR SENESCENCE IN HUMAN PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC)
AJ Kassianos, K Giuliani, P Nag, S Hong, X Wang, RL Johnston, B Adams, ...
Nephrology 28, 14-15, 2023
2023
HYPOXIA AND INTERLEUKIN (IL)-1 beta SENSITIZE PROXIMAL TUBULE EPITHELIAL CELLS (PTEC) TO TRANSFORMING GROWTH FACTOR (TGF)-beta SIGNALLING
KT Giuliani, RL Johnston, P Nag, A Grivei, MSY Ng, X Wang, J Ungerer, ...
NEPHROLOGY 27, 27-28, 2022
2022
BAICALEIN ATTENUATES ADENINE-INDUCED FERROPTOSIS IN HUMAN KIDNEY PRIMARY PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) VIA INDUCTION OF ANTIOXIDANT PATHWAYS
MA Khan, P Nag, KTK Giuliani, X Wang, A Grivei, W Hoy, H Healy, ...
NEPHROLOGY 26, 18-19, 2021
2021
INFLAMMASOME SIGNALLING IN HUMAN HYPOXIC CHRONIC KIDNEY DISEASE (CKD)
KTK Giuliani, A Grivei, P Nag, X Wang, J Ungerer, JM Forbes, H Healy, ...
NEPHROLOGY 26, 18-18, 2021
2021
POS-377 BAICALEIN ATTENUATES ADENINE-INDUCED FERROPTOSIS IN HUMAN KIDNEY PRIMARY PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) VIA MAINTENANCE OF HEME OXYGENASE-1 EXPRESSION
MA KHAN, P Nag, K Giuliani, X Wang, A Grivei, W Hoy, HG Healy, ...
Kidney International Reports 6 (4), S163, 2021
2021
POS-438 KIDNEYS ON FIRE: DECIPHERING THE ROLE OF INFLAMMASOME ACTIVATION IN HUMAN CHRONIC KIDNEY DISEASE (CKD)
K GIULIANI, A Grivei, P Nag, X Wang, AJ Kassianos, H Healy
Kidney International Reports 6 (4), S190-S191, 2021
2021
INDUCTION OF FERROPTOTIC DEATH IN HUMAN PRIMARY PROXIMAL TUBULAR EPITHELIAL CELLS (PTEC) DURING ADENINE-INDUCED CHRONIC KIDNEY DISEASE
MA Khan, P Nag, K Giuliani, XA Wang, A Grivei, W Hoy, H Healy, V Diwan, ...
NEPHROLOGY 25, 40-40, 2020
2020
Delineating the overlapping roles of the single-stranded DNA binding proteins Ssb1 and Ssb2 in the maintenance of genomic stability and intestinal homeostasis
P Nag
2019
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