|Toll-like receptor 4 signaling contributes to paclitaxel-induced peripheral neuropathy|
Y Li, H Zhang, H Zhang, AK Kosturakis, AB Jawad, PM Dougherty
The Journal of Pain 15 (7), 712-725, 2014
|Dorsal root ganglion infiltration by macrophages contributes to paclitaxel chemotherapy-induced peripheral neuropathy|
H Zhang, Y Li, M de Carvalho-Barbosa, A Kavelaars, CJ Heijnen, ...
The Journal of Pain 17 (7), 775-786, 2016
|The cancer chemotherapeutic paclitaxel increases human and rodent sensory neuron responses to TRPV1 by activation of TLR4|
Y Li, P Adamek, H Zhang, CE Tatsui, LD Rhines, P Mrozkova, Q Li, ...
Journal of Neuroscience 35 (39), 13487-13500, 2015
|Induction of monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 in primary sensory neurons contributes to paclitaxel-induced peripheral neuropathy|
H Zhang, JA Boyette-Davis, AK Kosturakis, Y Li, SY Yoon, ET Walters, ...
The Journal of Pain 14 (10), 1031-1044, 2013
|CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain|
K Krukowski, N Eijkelkamp, G Laumet, CE Hack, Y Li, PM Dougherty, ...
Journal of Neuroscience 36 (43), 11074-11083, 2016
|Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons|
RY North, Y Li, P Ray, LD Rhines, CE Tatsui, G Rao, CA Johansson, ...
Brain 142 (5), 1215-1226, 2019
|Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3. 2) in paclitaxel-induced peripheral neuropathy|
Y Li, CE Tatsui, LD Rhines, RY North, DS Harrison, RM Cassidy, ...
Pain 158 (3), 417, 2017
|DRG Voltage-Gated Sodium Channel 1.7 Is Upregulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain|
Y Li, RY North, LD Rhines, CE Tatsui, G Rao, DD Edwards, RM Cassidy, ...
Journal of Neuroscience 38 (5), 1124-1136, 2018
|MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy|
Y Li, H Zhang, AK Kosturakis, RM Cassidy, H Zhang, ...
Brain, behavior, and immunity 49, 255-266, 2015
|Nociceptor translational profiling reveals the Ragulator-Rag GTPase complex as a critical generator of neuropathic pain|
S Megat, PR Ray, JK Moy, TF Lou, P Barragán-Iglesias, Y Li, G Pradhan, ...
Journal of Neuroscience 39 (3), 393-411, 2019
|Formaldehyde up-regulates TRPV1 through MAPK and PI3K signaling pathways in a rat model of bone cancer pain|
Y Han, Y Li, X Xiao, J Liu, XL Meng, FY Liu, GG Xing, Y Wan
Neuroscience bulletin 28 (2), 165-172, 2012
|Enhanced function of TRPV1 via up‐regulation by insulin‐like growth factor‐1 in a rat model of bone cancer pain|
Y Li, J Cai, Y Han, X Xiao, XL Meng, L Su, FY Liu, GG Xing, Y Wan
European Journal of Pain 18 (6), 774-784, 2014
|Subclinical peripheral neuropathy in patients with multiple myeloma before chemotherapy is correlated with decreased fingertip innervation density|
AK Kosturakis, Z He, Y Li, JA Boyette-Davis, N Shah, SK Thomas, ...
Journal of Clinical Oncology 32 (28), 3156, 2014
|Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy|
P Singhmar, XJ Huo, Y Li, PM Dougherty, F Mei, X Cheng, CJ Heijnen, ...
Pain 159 (5), 884-893, 2018
|Morphological and physiological plasticity of spinal lamina II GABA neurons is induced by sciatic nerve chronic constriction injury in mice|
H Zhang, Y Li, Q Yang, XG Liu, PM Dougherty
Frontiers in Cellular Neuroscience 12, 143, 2018
|ACE2 expression in human dorsal root ganglion sensory neurons: implications for SARS-CoV-2 virus-induced neurological effects|
S Shiers, P Ray, A Wangzhou, CE Tatsui, L Rhines, Y Li, ML Uhelski, ...
|Chemotherapy-induced peripheral neuropathy in a dish: dorsal root ganglion cells treated in vitro with paclitaxel show biochemical and physiological responses parallel to that …|
Y Li, T Marri, RY North, HR Rhodes, ML Uhelski, CE Tatsui, LD Rhines, ...
Pain 162 (1), 84-96, 2020
|Studying human nociceptors: from fundamentals to clinic|
SJ Middleton, AM Barry, M Comini, Y Li, PR Ray, S Shiers, ...
|Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling|
D Zhang, W Zhou, TT Lam, Y Li, JG Duman, PM Dougherty, ...
Neuro-oncology advances 2 (1), vdaa058, 2020
|Role of innate immunity in chemotherapy-induced peripheral neuropathy|
ML Uhelski, Y Li, MM Fonseca, EA Romero-Snadoval, PM Dougherty
Neuroscience Letters, 135941, 2021