Non-covalent small-molecule Kelch-like ECH-associated protein 1–nuclear factor erythroid 2-related factor 2 (Keap1–Nrf2) inhibitors and their potential for targeting central … JS Pallesen, KT Tran, A Bach Journal of medicinal chemistry 61 (18), 8088-8103, 2018 | 86 | 2018 |
A comparative assessment study of known small-molecule Keap1− Nrf2 protein–protein interaction inhibitors: chemical synthesis, binding properties, and cellular activity KT Tran, JS Pallesen, SMØ Solbak, D Narayanan, A Baig, J Zang, ... Journal of medicinal chemistry 62 (17), 8028-8052, 2019 | 72 | 2019 |
Deconstructing noncovalent Kelch-like ECH-associated protein 1 (Keap1) inhibitors into fragments to reconstruct new potent compounds JS Pallesen, D Narayanan, KT Tran, SMØ Solbak, G Marseglia, ... Journal of medicinal chemistry 64 (8), 4623-4661, 2021 | 31 | 2021 |
Development of noncovalent small-molecule Keap1-Nrf2 inhibitors by fragment-based drug discovery D Narayanan, KT Tran, JS Pallesen, SMØ Solbak, Y Qin, E Mukminova, ... Journal of medicinal chemistry 65 (21), 14481-14526, 2022 | 15 | 2022 |
Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening SW Lee, KT Tran, R Vazquez-Uribe, CH Gotfredsen, MH Clausen, ... Journal of Medicinal Chemistry 65 (4), 3266-3305, 2022 | 5 | 2022 |