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Kim Tai Tran
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Non-covalent small-molecule Kelch-like ECH-associated protein 1–nuclear factor erythroid 2-related factor 2 (Keap1–Nrf2) inhibitors and their potential for targeting central …
JS Pallesen, KT Tran, A Bach
Journal of medicinal chemistry 61 (18), 8088-8103, 2018
862018
A comparative assessment study of known small-molecule Keap1− Nrf2 protein–protein interaction inhibitors: chemical synthesis, binding properties, and cellular activity
KT Tran, JS Pallesen, SMØ Solbak, D Narayanan, A Baig, J Zang, ...
Journal of medicinal chemistry 62 (17), 8028-8052, 2019
722019
Deconstructing noncovalent Kelch-like ECH-associated protein 1 (Keap1) inhibitors into fragments to reconstruct new potent compounds
JS Pallesen, D Narayanan, KT Tran, SMØ Solbak, G Marseglia, ...
Journal of medicinal chemistry 64 (8), 4623-4661, 2021
312021
Development of noncovalent small-molecule Keap1-Nrf2 inhibitors by fragment-based drug discovery
D Narayanan, KT Tran, JS Pallesen, SMØ Solbak, Y Qin, E Mukminova, ...
Journal of medicinal chemistry 65 (21), 14481-14526, 2022
152022
Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening
SW Lee, KT Tran, R Vazquez-Uribe, CH Gotfredsen, MH Clausen, ...
Journal of Medicinal Chemistry 65 (4), 3266-3305, 2022
52022
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