| The classical complement cascade mediates CNS synapse elimination B Stevens, NJ Allen, LE Vazquez, GR Howell, KS Christopherson, ... Cell 131 (6), 1164-1178, 2007 | 3181 | 2007 |
| The DNA sequence of the human X chromosome MT Ross, DV Grafham, AJ Coffey, S Scherer, K McLay, D Muzny, ... Nature 434 (7031), 325-337, 2005 | 1383 | 2005 |
| Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene AJ Coffey, RA Brooksbank, O Brandau, T Oohashi, GR Howell, JM Bye, ... Nature genetics 20 (2), 129-135, 1998 | 877 | 1998 |
| TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse modelsTREM2 expression and function in AD TR Jay, CM Miller, PJ Cheng, LC Graham, S Bemiller, ML Broihier, G Xu, ... The Journal of experimental medicine 212 (3), 287-295, 2015 | 691 | 2015 |
| Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma GR Howell, RT Libby, TC Jakobs, RS Smith, FC Phalan, JW Barter, ... The Journal of cell biology 179 (7), 1523-1537, 2007 | 621 | 2007 |
| The DNA sequence and analysis of human chromosome 6 AJ Mungall, SA Palmer, SK Sims, CA Edwards, JL Ashurst, L Wilming, ... Nature 425 (6960), 805-811, 2003 | 535 | 2003 |
| Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma GR Howell, DG Macalinao, GL Sousa, M Walden, I Soto, SC Kneeland, ... The Journal of clinical investigation 121 (4), 1429-1444, 2011 | 461 | 2011 |
| Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model CA Tagge, AM Fisher, OV Minaeva, A Gaudreau-Balderrama, ... Brain 141 (2), 422-458, 2018 | 418 | 2018 |
| Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy RW Nickells, GR Howell, I Soto, SWM John Annual review of neuroscience 35, 153-179, 2012 | 370 | 2012 |
| A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation A Carrié, L Jun, T Bienvenu, MC Vinet, N McDonell, P Couvert, R Zemni, ... Nature genetics 23 (1), 25-31, 1999 | 341 | 1999 |
| Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma JNC Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, ... Nature genetics 48 (2), 189-194, 2016 | 257 | 2016 |
| A robust system for RNA interference in the chicken using a modified microRNA operon RM Das, NJ Van Hateren, GR Howell, ER Farrell, FK Bangs, VC Porteous, ... Developmental biology 294 (2), 554-563, 2006 | 240 | 2006 |
| Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma GR Howell, I Soto, X Zhu, M Ryan, DG Macalinao, GL Sousa, LB Caddle, ... The Journal of clinical investigation 122 (4), 1246-1261, 2012 | 227 | 2012 |
| Neuroinflammation in glaucoma: A new opportunity PA Williams, N Marsh-Armstrong, GR Howell, A Bosco, J Danias, J Simon, ... Experimental eye research 157, 20-27, 2017 | 222 | 2017 |
| The complex role of neuroinflammation in glaucoma I Soto, GR Howell Cold Spring Harbor perspectives in medicine 4 (8), a017269, 2014 | 218 | 2014 |
| Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 107908, 2020 | 209 | 2020 |
| Mutations in the RNA granule component TDRD7 cause cataract and glaucoma SA Lachke, FS Alkuraya, SC Kneeland, T Ohn, A Aboukhalil, GR Howell, ... Science 331 (6024), 1571-1576, 2011 | 206 | 2011 |
| Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma PA Williams, JR Tribble, KW Pepper, SD Cross, BP Morgan, JE Morgan, ... Molecular neurodegeneration 11, 1-13, 2016 | 173 | 2016 |
| Toward more predictive genetic mouse models of Alzheimer's disease KD Onos, SJS Rizzo, GR Howell, M Sasner Brain research bulletin 122, 1-11, 2016 | 169 | 2016 |
| Comprehensive evaluation of the 5XFAD mouse model for preclinical testing applications: a MODEL-AD study AL Oblak, PB Lin, KP Kotredes, RS Pandey, D Garceau, HM Williams, ... Frontiers in aging neuroscience 13, 713726, 2021 | 161 | 2021 |
Simon WM JohnProfessor of Ophthalmology, Columbia UniversityVerified email at cumc.columbia.edu
