Stephen Mack
TitleCited byYear
Medulloblastoma comprises four distinct molecular variants
PA Northcott, A Korshunov, H Witt, T Hielscher, CG Eberhart, S Mack, ...
Journal of Clinical Oncology 29 (11), 1408, 2011
10052011
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49, 2012
5762012
Cancer stem cells in glioblastoma
JD Lathia, SC Mack, EE Mulkearns-Hubert, CLL Valentim, JN Rich
Genes & development 29 (12), 1203-1217, 2015
5602015
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups
KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ...
Cancer cell 27 (5), 728-743, 2015
4282015
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ...
Nature genetics 41 (4), 465, 2009
3992009
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
3892014
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ...
Cancer cell 20 (2), 143-157, 2011
3372011
Cross-species genomics matches driver mutations and cell compartments to model ependymoma
RA Johnson, KD Wright, H Poppleton, KM Mohankumar, D Finkelstein, ...
Nature 466 (7306), 632, 2010
2972010
Cytogenetic prognostication within medulloblastoma subgroups
DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ...
Journal of clinical oncology 32 (9), 886, 2014
1922014
Divergent clonal selection dominates medulloblastoma at recurrence
AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ...
Nature 529 (7586), 351, 2016
1802016
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
PA Northcott, T Hielscher, A Dubuc, S Mack, D Shih, M Remke, ...
Acta neuropathologica 122 (2), 231-240, 2011
1722011
Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
P Castelo-Branco, S Choufani, S Mack, D Gallagher, C Zhang, T Lipman, ...
The lancet oncology 14 (6), 534-542, 2013
1542013
A three-dimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo
CG Hubert, M Rivera, LC Spangler, Q Wu, SC Mack, BC Prager, M Couce, ...
Cancer research 76 (8), 2465-2477, 2016
1372016
The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants
KW Pajtler, SC Mack, V Ramaswamy, CA Smith, H Witt, A Smith, ...
Acta neuropathologica 133 (1), 5-12, 2017
1162017
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126 (6), 917-929, 2013
1102013
Preferential iron trafficking characterizes glioblastoma stem-like cells
DL Schonberg, TE Miller, Q Wu, WA Flavahan, NK Das, JS Hale, ...
Cancer cell 28 (4), 441-455, 2015
1072015
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
X Jin, LJY Kim, Q Wu, LC Wallace, BC Prager, T Sanvoranart, RC Gimple, ...
Nature medicine 23 (11), 1352, 2017
922017
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ...
Nature 547 (7663), 355, 2017
782017
Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis
V Ramaswamy, T Hielscher, SC Mack, A Lassaletta, T Lin, KW Pajtler, ...
Journal of Clinical Oncology 34 (21), 2468, 2016
772016
The genetics of pediatric brain tumors
AM Dubuc, PA Northcott, S Mack, H Witt, S Pfister, MD Taylor
Current neurology and neuroscience reports 10 (3), 215-223, 2010
762010
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