| Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis HH Jarosz-Griffiths, T Scambler, CH Wong, S Lara-Reyna, J Holbrook, ... Elife 9, e54556, 2020 | 97 | 2020 |
| ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis T Scambler, HH Jarosz-Griffiths, S Lara-Reyna, S Pathak, C Wong, ... Elife 8, e49248, 2019 | 90 | 2019 |
| Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome DM Rowczenio, S Pathak, JI Arostegui, A Mensa-Vilaro, E Omoyinmi, ... Blood, The Journal of the American Society of Hematology 131 (9), 974-981, 2018 | 90 | 2018 |
| The burgeoning field of innate immune‐mediated disease and autoinflammation D Peckham, T Scambler, S Savic, MF McDermott The Journal of pathology 241 (2), 123-139, 2017 | 85 | 2017 |
| Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin T Tang, TE Scambler, T Smallie, HE Cunliffe, EA Ross, DR Rosner, ... Scientific reports 7 (1), 4350, 2017 | 83 | 2017 |
| Metabolic reprograming of cystic fibrosis macrophages via the IRE1α arm of the unfolded protein response results in exacerbated inflammation S Lara-Reyna, T Scambler, J Holbrook, C Wong, HH Jarosz-Griffiths, ... Frontiers in immunology 10, 460242, 2019 | 49 | 2019 |
| Autoinflammatory disease in the lung T Scambler, J Holbrook, S Savic, MF McDermott, D Peckham Immunology 154 (4), 563-573, 2018 | 35 | 2018 |
| A case of adult-onset Still’s disease caused by a novel splicing mutation in TNFAIP3 successfully treated with tocilizumab D Lawless, S Pathak, TE Scambler, L Ouboussad, R Anwar, S Savic Frontiers in Immunology 9, 372267, 2018 | 32 | 2018 |
| Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations … SR Harrison, T Scambler, L Oubussad, C Wong, M Wittmann, ... Frontiers in immunology 9, 173, 2018 | 21 | 2018 |
| Glucose-6-Phosphatase Catalytic Subunit 3 (G6PC3) Deficiency Associated With Autoinflammatory Complications A Mistry, T Scambler, D Parry, M Wood, G Barcenas-Morales, C Carter, ... Frontiers in Immunology 8, 1485, 2017 | 17 | 2017 |
| Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in cystic fibrosis T Scambler, HH Jarosz-Griffiths, S Lara-Reyna, S Pathak, C Wong, ... bioRxiv, 458208, 2018 | 2 | 2018 |
| Regulation of the unfolded protein response in disease: cellular stress and microRNAs S Lara-Reyna, T Scambler, J Holbrook, HH Jarosz-Griffiths, D Peckham, ... Current Immunology Reviews 14 (1), 3-14, 2018 | 1 | 2018 |
| Protection against lupus-like inflammatory disease is in the LAP of non-canonical autophagy T Scambler, C Feeley, MF McDermott Annals of Translational Medicine 4 (24), 2016 | 1 | 2016 |
| WS12. 6 Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis H Jarosz-Griffiths, T Scambler, C Wong, S Lara-Reyna, J Holbrook, ... Journal of Cystic Fibrosis, 2020 | | 2020 |
| WS08-4 Metabolic reprogramming of cystic fibrosis macrophages by the IRE1α-XBP1 pathway leads to an exaggerated inflammatory response SL Reyna, T Scambler, J Holbrook, H Jarosz-Griffiths, C Wong, F Martinon, ... Journal of Cystic Fibrosis 18, S15, 2019 | | 2019 |
| P028 Autophagy in cystic fibrosis J Holbrook, S Lara-Reyna, HH Jarosz-Griffiths, C Wong, T Scambler, ... Journal of Cystic Fibrosis 18, S64-S65, 2019 | | 2019 |
| S138 Inhibition of auto-inflammation in cystic fibrosis using small molecule therapy H Jarosz-Griffiths, T Scambler, J Holbrook, SL Reyna, C Wong, S Savic, ... Thorax 73 (Suppl 4), A86-A86, 2018 | | 2018 |
| Enac modulates innate immune inflammation and metabolism in cystic fibrosis T Scambler, C Wong, S Pathak, S Lara Reyna, J Holbrook, ... Pediatric Pulmonology 53 (S2), 184-185, 2018 | | 2018 |
| The effect of cysteamine and epigallocatechin gallate on the inflammatory phenotype in cystic fibrosis J Holbrook, T Scambler, S Lara Reyna, C Wong, H Jarosz-Griffiths, ... Pediatric Pulmonology 53 (S2), 245-245, 2018 | | 2018 |
| Overactivation of IRE1α drives overexpression of IL-6 in cystic fibrosis S Lara Reyna, T Scambler, J Holbrook, H Jarosz-Griffiths, C Wong, ... Pediatric Pulmonology 53 (S2), 189-189, 2018 | | 2018 |
Sinisa SavicProfessor of clinical immunologyVerified email at leeds.ac.uk
