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James Wells
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Year
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
JR Spence, CN Mayhew, SA Rankin, MF Kuhar, JE Vallance, K Tolle, ...
Nature 470 (7332), 105-109, 2011
20002011
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
KW McCracken, EM Catá, CM Crawford, KL Sinagoga, M Schumacher, ...
Nature 516 (7531), 400-404, 2014
10162014
Vertebrate endoderm development and organ formation
AM Zorn, JM Wells
Annual Review of Cell and Developmental 25, 221-251, 2009
9062009
In vitro generation of human pluripotent stem cell derived lung organoids
BR Dye, DR Hill, MAH Ferguson, YH Tsai, MS Nagy, R Dyal, JM Wells, ...
elife 4, e05098, 2015
7692015
Vertebrate endoderm development
JM Wells, DA Melton
Annual review of cell and developmental biology 15 (1), 393-410, 1999
7211999
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
MJ Workman, MM Mahe, S Trisno, HM Poling, CL Watson, N Sundaram, ...
Nature medicine 23 (1), 49-59, 2017
5842017
An in vivo model of human small intestine using pluripotent stem cells
CL Watson, MM Mahe, J Múnera, JC Howell, N Sundaram, HM Poling, ...
Nature medicine 20 (11), 1310-1314, 2014
5652014
Early mouse endoderm is patterned by soluble factors from adjacent germ layers
JM Wells, DA Melton
Development 127 (8), 1563-1572, 2000
5502000
Generating human intestinal tissue from pluripotent stem cells in vitro
KW McCracken, JC Howell, JM Wells, JR Spence
Nature protocols 6 (12), 1920-1928, 2011
4542011
Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids
R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ...
Cell metabolism 30 (2), 374-384. e6, 2019
3912019
Sox17 and Sox4 differentially regulate β-catenin/T-cell factor activity and proliferation of colon carcinoma cells
D Sinner, JJ Kordich, JR Spence, R Opoka, S Rankin, SCJ Lin, D Jonatan, ...
Molecular and cellular biology 27 (22), 7802-7815, 2007
3822007
Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
AE Serls, S Doherty, P Parvatiyar, JM Wells, GH Deutsch
Oxford University Press for The Company of Biologists Limited 132 (1), 35-47, 2005
3732005
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells
JR Spence, AW Lange, SCJ Lin, KH Kaestner, AM Lowy, I Kim, ...
Developmental cell 17 (1), 62-74, 2009
3392009
Organoids by design
T Takebe, JM Wells
Science 364 (6444), 956-959, 2019
3142019
Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish
HA McCauley, JM Wells
Development 144 (6), 958-962, 2017
3032017
Global expression analysis of gene regulatory pathways during endocrine pancreatic development
G Gu, JM Wells, D Dombkowski, F Preffer, B Aronow, DA Melton
Oxford University Press for The Company of Biologists Limited 131 (1), 165-179, 2004
2952004
Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary
H Koike, K Iwasawa, R Ouchi, M Maezawa, K Giesbrecht, N Saiki, ...
Nature 574 (7776), 112-116, 2019
2612019
Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling
JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson, M Mahe, ...
Cell stem cell 21 (1), 51-64. e6, 2017
2522017
Wnt/β-catenin promotes gastric fundus specification in mice and humans
KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, ...
Nature 541 (7636), 182-187, 2017
2422017
FGF signaling is necessary for establishing gut tube domains alongthe anterior–posterior axis in vivo
J Dessimoz, R Opoka, JJ Kordich, A Grapin-Botton, JM Wells
Mechanisms of development 123 (1), 42-55, 2006
2412006
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Articles 1–20