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Madison Adolph
Madison Adolph
Verified email at vanderbilt.edu
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Year
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis
GJ Starrett, EM Luengas, JL McCann, D Ebrahimi, NA Temiz, RP Love, ...
Nature communications 7 (1), 12918, 2016
1662016
A single nucleotide polymorphism in human APOBEC3C enhances restriction of lentiviruses
CJ Wittkopp, MB Adolph, LI Wu, L Chelico, M Emerman
PLoS pathogens 12 (10), e1005865, 2016
652016
Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B
MB Adolph, RP Love, Y Feng, L Chelico
Nucleic acids research 45 (20), 11925-11940, 2017
562017
Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase
MB Adolph, J Webb, L Chelico
PloS one 8 (5), e64196, 2013
532013
Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure
YZ McDaniel, D Wang, RP Love, MB Adolph, N Mohammadzadeh, ...
Nucleic acids research 48 (3), 1353-1371, 2020
502020
Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization
MB Adolph, A Ara, Y Feng, CJ Wittkopp, M Emerman, JS Fraser, L Chelico
Nucleic acids research 45 (6), 3378-3394, 2017
482017
Mechanism of enhanced HIV restriction by virion coencapsidated cytidine deaminases APOBEC3F and APOBEC3G
A Ara, RP Love, TB Follack, KA Ahmed, MB Adolph, L Chelico
Journal of virology 91 (3), 10.1128/jvi. 02230-16, 2017
482017
Natural polymorphisms and oligomerization of human APOBEC3H contribute to single-stranded DNA scanning ability
Y Feng, RP Love, A Ara, TT Baig, MB Adolph, L Chelico
Journal of Biological Chemistry 290 (45), 27188-27203, 2015
452015
Biochemical basis of APOBEC3 deoxycytidine deaminase activity on diverse DNA substrates
MB Adolph, RP Love, L Chelico
ACS infectious diseases 4 (3), 224-238, 2018
422018
RADX controls RAD51 filament dynamics to regulate replication fork stability
MB Adolph, TM Mohamed, S Balakrishnan, C Xue, F Morati, M Modesti, ...
Molecular cell 81 (5), 1074-1083. e5, 2021
272021
RADX prevents genome instability by confining replication fork reversal to stalled forks
A Krishnamoorthy, J Jackson, T Mohamed, M Adolph, A Vindigni, ...
Molecular cell 81 (14), 3007-3017. e5, 2021
252021
APOBEC3 host restriction factors of HIV-1 can change the template switching frequency of reverse transcriptase
MB Adolph, A Ara, L Chelico
Journal of molecular biology 431 (7), 1339-1352, 2019
92019
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis. Nat Commun 7: 12918
GJ Starrett, EM Luengas, JL McCann, D Ebrahimi, NA Temiz, RP Love, ...
92016
APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response
KL Conner, AN Shaik, KA Marshall, AM Floyd, E Ekinci, J Lindquist, ...
NAR cancer 2 (4), zcaa033, 2020
62020
Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability
T Mohamed, MB Adolph, D Cortez
Journal of Biological Chemistry 298 (3), 2022
42022
Corrigendum: Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.
MB Adolph, RP Love, Y Feng, L Chelico
Nucleic Acids Research 46 (22), 12190-12191, 2018
22018
Structure of RADX and mechanism for regulation of RAD51 nucleofilaments
S Balakrishnan, M Adolph, MS Tsai, T Akizuki, K Gallagher, D Cortez, ...
Proceedings of the National Academy of Sciences 121 (12), e2316491121, 2024
2024
Abstract IA024: Mechanistic insights into how RADX regulates RAD51 nucleoprotein filaments to maintain genome stability and control replication stress responses
M Adolph, S Balakrishnan, W Chazin, D Cortez
Cancer Research 84 (1_Supplement), IA024-IA024, 2024
2024
Mechanistic insights into how RADX regulates RAD51 nucleoprotein filaments to maintain genome stability and control replication stress responses
M Adolph, S Balakrishnan, W Chazin, D Cortez
CANCER RESEARCH 84 (1), 2024
2024
CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
MB Adolph, AS Garje, S Balakrishnan, F Morati, M Modesti, WJ Chazin, ...
Journal of Molecular Biology 435 (19), 168236, 2023
2023
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