Heyu Ni
Heyu Ni
Scientist, Canadian Blood Services & St. Michael's Hospital; Professor, University of Toronto
Verified email at
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Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
H Ni, CV Denis, S Subbarao, JL Degen, TN Sato, RO Hynes, DD Wagner
The Journal of clinical investigation 106 (3), 385-392, 2000
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
R Aslam, ER Speck, M Kim, AR Crow, KWA Bang, FP Nestel, H Ni, ...
Blood 107 (2), 637-641, 2006
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia
J Li, DE Van Der Wal, G Zhu, M Xu, I Yougbare, L Ma, B Vadasz, N Carrim, ...
Nature communications 6 (1), 7737, 2015
Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond
XR Xu, D Zhang, BE Oswald, N Carrim, X Wang, Y Hou, Q Zhang, ...
Critical reviews in clinical laboratory sciences 53 (6), 409-430, 2016
Plasma fibronectin promotes thrombus growth and stability in injured arterioles
H Ni, PST Yuen, JM Papalia, JE Trevithick, T Sakai, R Fässler, RO Hynes, ...
Proceedings of the National Academy of Sciences 100 (5), 2415-2419, 2003
Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents
XR Xu, GM Yousef, H Ni
Blood, The Journal of the American Society of Hematology 131 (16), 1777-1789, 2018
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice
J Chen, A Reheman, FC Gushiken, L Nolasco, X Fu, JL Moake, H Ni, ...
The Journal of clinical investigation 121 (2), 593-603, 2011
Platelets in hemostasis and thrombosis: role of integrins and their ligands
H Ni, J Freedman
Transfusion and Apheresis Science 28 (3), 257-264, 2003
Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPARα
S Sethi, O Ziouzenkova, H Ni, DD Wagner, J Plutzky, TN Mayadas
Blood, The Journal of the American Society of Hematology 100 (4), 1340-1346, 2002
A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy
L Chow, R Aslam, ER Speck, M Kim, N Cridland, ML Webster, P Chen, ...
Blood, The Journal of the American Society of Hematology 115 (6), 1247-1253, 2010
Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis
Y Hou, N Carrim, Y Wang, RC Gallant, A Marshall, H Ni
Journal of biomedical research 29 (6), 437, 2015
Plasma fibronectin supports hemostasis and regulates thrombosis
Y Wang, A Reheman, CM Spring, J Kalantari, AH Marshall, AS Wolberg, ...
The Journal of clinical investigation 124 (10), 4281-4293, 2014
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis
AJ Murphy, N Bijl, L Yvan-Charvet, CB Welch, N Bhagwat, A Reheman, ...
Nature medicine 19 (5), 586-594, 2013
Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies
ML Webster, E Sayeh, M Crow, P Chen, B Nieswandt, J Freedman, H Ni
Blood 108 (3), 943-946, 2006
Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies
XR Xu, N Carrim, MAD Neves, T McKeown, TW Stratton, RMP Coelho, ...
Thrombosis journal 14, 37-46, 2016
Crosstalk between platelets and the immune system: old systems with new discoveries
C Li, J Li, Y Li, S Lang, I Yougbare, G Zhu, P Chen, H Ni
Advances in hematology 2012, 2012
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking
JR Byrnes, C Duval, Y Wang, CE Hansen, B Ahn, MJ Mooberry, MA Clark, ...
Blood, The Journal of the American Society of Hematology 126 (16), 1940-1948, 2015
Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the β1Integrin chain
H Ni, A Li, N Simonsen, JA Wilkins
Journal of Biological Chemistry 273 (14), 7981-7987, 1998
Vitronectin stabilizes thrombi and vessel occlusion but plays a dual role in platelet aggregation
A Reheman, P Gross, H Yang, P Chen, D Allen, V Leytin, J Freedman, ...
Journal of Thrombosis and Haemostasis 3 (5), 875-883, 2005
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis
X Lei, A Reheman, Y Hou, H Zhou, Y Wang, AH Marshall, C Liang, X Dai, ...
Thromb Haemost 111 (2), 279-289, 2014
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