Proteome-wide identification of poly (ADP-ribose) binding proteins and poly (ADP-ribose)-associated protein complexes JP Gagne, M Isabelle, KS Lo, S Bourassa, MJ Hendzel, VL Dawson, ... Nucleic acids research 36 (22), 6959-6976, 2008 | 478 | 2008 |
Poly (ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis SA Andrabi, GKE Umanah, C Chang, DA Stevens, SS Karuppagounder, ... Proceedings of the National Academy of Sciences 111 (28), 10209-10214, 2014 | 340 | 2014 |
Iduna is a poly (ADP-ribose)(PAR)-dependent E3 ubiquitin ligase that regulates DNA damage HC Kang, YI Lee, JH Shin, SA Andrabi, Z Chi, JP Gagné, Y Lee, HS Ko, ... Proceedings of the National Academy of Sciences 108 (34), 14103-14108, 2011 | 252 | 2011 |
Germline mutations in BAP1 impair its function in DNA double-strand break repair IH Ismail, R Davidson, JP Gagné, ZZ Xu, GG Poirier, MJ Hendzel Cancer research 74 (16), 4282-4294, 2014 | 229 | 2014 |
ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion E Fouquerel, EM Goellner, Z Yu, JP Gagne, MB de Moura, T Feinstein, ... Cell reports 8 (6), 1819-1831, 2014 | 217 | 2014 |
Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry M Isabelle, X Moreel, JP Gagné, M Rouleau, C Ethier, P Gagné, ... Proteome science 8, 1-11, 2010 | 202 | 2010 |
Reprogramming cellular events by poly (ADP-ribose)-binding proteins J Krietsch, M Rouleau, É Pic, C Ethier, TM Dawson, VL Dawson, ... Molecular aspects of medicine 34 (6), 1066-1087, 2013 | 196 | 2013 |
ADP‐ribosyltransferases, an update on function and nomenclature B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ... The FEBS journal 289 (23), 7399-7410, 2022 | 181 | 2022 |
Quantitative proteomics profiling of the poly (ADP-ribose)-related response to genotoxic stress JP Gagne, E Pic, M Isabelle, J Krietsch, C Ethier, E Paquet, I Kelly, ... Nucleic acids research 40 (16), 7788-7805, 2012 | 177 | 2012 |
PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks J Krietsch, MC Caron, JP Gagne, C Ethier, J Vignard, M Vincent, ... Nucleic acids research 40 (20), 10287-10301, 2012 | 170 | 2012 |
Poly (ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks MC Caron, AK Sharma, J O’Sullivan, LR Myler, MT Ferreira, A Rodrigue, ... Nature communications 10 (1), 2954, 2019 | 160 | 2019 |
The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice IH Ismail, JP Gagné, MM Genois, H Strickfaden, D McDonald, Z Xu, ... Nature cell biology 17 (11), 1446-1457, 2015 | 147 | 2015 |
The expanding role of poly (ADP-ribose) metabolism: current challenges and new perspectives JP Gagné, MJ Hendzel, A Droit, GG Poirier Current opinion in cell biology 18 (2), 145-151, 2006 | 147 | 2006 |
Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation J O’Sullivan, M Tedim Ferreira, JP Gagné, AK Sharma, MJ Hendzel, ... Nature Communications 10 (1), 1182, 2019 | 140 | 2019 |
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage IH Ismail, JP Gagné, MC Caron, D McDonald, Z Xu, JY Masson, ... Nucleic acids research 40 (12), 5497-5510, 2012 | 139 | 2012 |
Poly (ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation S Wieler, JP Gagné, H Vaziri, GG Poirier, S Benchimol Journal of Biological Chemistry 278 (21), 18914-18921, 2003 | 138 | 2003 |
A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly (ADP-ribose)-binding proteins JP Gagné, JM Hunter, B Labrecque, B Chabot, GG Poirier Biochemical Journal 371 (2), 331-340, 2003 | 138 | 2003 |
Mapping PARP-1 auto-ADP-ribosylation sites by liquid chromatography–tandem mass spectrometry JD Chapman, JP Gagné, GG Poirier, DR Goodlett Journal of proteome research 12 (4), 1868-1880, 2013 | 112 | 2013 |
The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase YMO Alhammad, MM Kashipathy, A Roy, JP Gagné, P McDonald, P Gao, ... Journal of virology 95 (3), 10.1128/jvi. 01969-20, 2021 | 95 | 2021 |
Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly (ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation M Isabelle, JP Gagné, IE Gallouzi, GG Poirier Journal of cell science 125 (19), 4555-4566, 2012 | 85 | 2012 |