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William A Flavahan
William A Flavahan
Assistant Professor, University of Massachusetts Chan Medical School
Verified email at umassmed.edu - Homepage
Title
Cited by
Cited by
Year
Insulator dysfunction and oncogene activation in IDH mutant gliomas
WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ...
Nature 529 (7584), 110-114, 2016
12482016
Epigenetic plasticity and the hallmarks of cancer
WA Flavahan, E Gaskell, BE Bernstein
Science 357 (6348), eaal2380, 2017
11462017
Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
W Zhou, SQ Ke, Z Huang, W Flavahan, X Fang, J Paul, L Wu, AE Sloan, ...
Nature cell biology 17 (2), 170-182, 2015
8242015
Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake
WA Flavahan, Q Wu, M Hitomi, N Rahim, Y Kim, AE Sloan, RJ Weil, ...
Nature neuroscience 16 (10), 1373-1382, 2013
4882013
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell stem cell 20 (2), 233-246. e7, 2017
4642017
Mitochondrial control by DRP1 in brain tumor initiating cells
Q Xie, Q Wu, CM Horbinski, WA Flavahan, K Yang, W Zhou, ...
Nature neuroscience 18 (4), 501-510, 2015
3632015
Preferential iron trafficking characterizes glioblastoma stem-like cells
DL Schonberg, TE Miller, Q Wu, WA Flavahan, NK Das, JS Hale, ...
Cancer cell 28 (4), 441-455, 2015
2872015
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression
JS Hale, B Otvos, M Sinyuk, AG Alvarado, M Hitomi, K Stoltz, Q Wu, ...
Stem cells 32 (7), 1746-1758, 2014
2342014
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ...
Stem cells 34 (8), 2026-2039, 2016
2192016
Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells
M Venere, P Hamerlik, Q Wu, RD Rasmussen, LA Song, A Vasanji, ...
Cell Death & Differentiation 21 (2), 258-269, 2014
1962014
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ...
Nature 547 (7663), 355-359, 2017
1912017
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs
WA Flavahan, Y Drier, SE Johnstone, ML Hemming, DR Tarjan, E Hegazi, ...
Nature 575 (7781), 229-233, 2019
1902019
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ...
Nature neuroscience 20 (5), 661-673, 2017
1702017
Differential connexin function enhances self-renewal in glioblastoma
M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ...
Cell reports 11 (7), 1031-1042, 2015
1172015
Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction
NA Flavahan, SR Bailey, WA Flavahan, S Mitra, S Flavahan
American Journal of Physiology-Heart and Circulatory Physiology 288 (2 …, 2005
932005
High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor
JD Lathia, M Li, M Sinyuk, AG Alvarado, WA Flavahan, K Stoltz, ...
Cell reports 6 (1), 117-129, 2014
872014
Epigenome editing strategies for the functional annotation of CTCF insulators
DR Tarjan, WA Flavahan, BE Bernstein
Nature communications 10 (1), 4258, 2019
632019
CDC20 maintains tumor initiating cells
Q Xie, Q Wu, SC Mack, K Yang, L Kim, CG Hubert, WA Flavahan, C Chu, ...
Oncotarget 6 (15), 13241, 2015
562015
Salmonella Typhi colonization provokes extensive transcriptional changes aimed at evading host mucosal immune defense during early infection of human intestinal tissue
KP Nickerson, S Senger, Y Zhang, R Lima, S Patel, L Ingano, ...
EBioMedicine 31, 92-109, 2018
522018
Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells
Y Bai, JD Lathia, P Zhang, W Flavahan, JN Rich, MP Mattson
Glia 62 (10), 1687-1698, 2014
472014
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