| An update on sphingosine-1-phosphate and other sphingolipid mediators H Fyrst, JD Saba Nature chemical biology 6 (7), 489-497, 2010 | 414 | 2010 |
| Point-counterpoint of sphingosine 1-phosphate metabolism JD Saba, T Hla Circulation research 94 (6), 724-734, 2004 | 334 | 2004 |
| The BST1 Gene of Saccharomyces cerevisiaeis the sphingosine-1-phosphate lyase JD Saba, F Nara, A Bielawska, S Garrett, YA Hannun Journal of Biological Chemistry 272 (42), 26087-26090, 1997 | 289 | 1997 |
| γ-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis Q Jiang, J Wong, H Fyrst, JD Saba, BN Ames Proceedings of the National Academy of Sciences 101 (51), 17825-17830, 2004 | 278 | 2004 |
| Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation M Kohno, M Momoi, ML Oo, JH Paik, YM Lee, K Venkataraman, Y Ai, ... Molecular and cellular biology, 2006 | 273 | 2006 |
| Sphingosine-1-phosphate lyase potentiates apoptosis via p53-and p38-dependent pathways and is down-regulated in colon cancer B Oskouian, P Sooriyakumaran, AD Borowsky, A Crans, L Dillard-Telm, ... Proceedings of the National Academy of Sciences 103 (46), 17384-17389, 2006 | 253 | 2006 |
| Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver M Bektas, ML Allende, BG Lee, WP Chen, MJ Amar, AT Remaley, ... Journal of Biological Chemistry 285 (14), 10880-10889, 2010 | 215 | 2010 |
| Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking ML Allende, M Bektas, BG Lee, E Bonifacino, J Kang, G Tuymetova, ... Journal of Biological Chemistry 286 (9), 7348-7358, 2011 | 212 | 2011 |
| Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells M Tauseef, V Kini, N Knezevic, M Brannan, R Ramchandaran, H Fyrst, ... Circulation research 103 (10), 1164-1172, 2008 | 211 | 2008 |
| Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast J Zhou, JD Saba Biochemical and biophysical research communications 242 (3), 502-507, 1998 | 202 | 1998 |
| Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function M Serra, JD Saba Advances in enzyme regulation 50 (1), 349-362, 2010 | 197 | 2010 |
| Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency S Lovric, S Goncalves, HY Gee, B Oskouian, H Srinivas, WI Choi, S Shril, ... The Journal of clinical investigation 127 (3), 912-928, 2017 | 193 | 2017 |
| The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity P Bandhuvula, YY Tam, B Oskouian, JD Saba Journal of Biological Chemistry 280 (40), 33697-33700, 2005 | 185 | 2005 |
| Cancer treatment strategies targeting sphingolipid metabolism B Oskouian, JD Saba Sphingolipids as Signaling and Regulatory Molecules, 185-205, 2010 | 180 | 2010 |
| Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis U Reiss, B Oskouian, J Zhou, V Gupta, P Sooriyakumaran, S Kelly, ... Journal of Biological Chemistry 279 (2), 1281-1290, 2004 | 174 | 2004 |
| Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs E Degagné, A Pandurangan, P Bandhuvula, A Kumar, A Eltanawy, ... The Journal of clinical investigation 124 (12), 5368-5384, 2014 | 149 | 2014 |
| Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren P Bandhuvula, JD Saba Trends in molecular medicine 13 (5), 210-217, 2007 | 149 | 2007 |
| The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses C MAO, JD SABA, LM OBEID Biochemical Journal 342 (3), 667-675, 1999 | 143 | 1999 |
| Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania K Zhang, JM Pompey, FF Hsu, P Key, P Bandhuvula, JD Saba, J Turk, ... The EMBO journal 26 (4), 1094-1104, 2007 | 136 | 2007 |
| Sply regulation of sphingolipid signaling molecules is essential for Drosophila development DR Herr, H Fyrst, V Phan, K Heinecke, R Georges, GL Harris, JD Saba Oxford University Press for The Company of Biologists Limited 130 (11), 2443 …, 2003 | 134 | 2003 |
