Marc Prentki
Marc Prentki
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A genome-wide association study identifies novel risk loci for type 2 diabetes
R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D Serre, P Boutin, ...
Nature 445 (7130), 881-885, 2007
Islet β cell failure in type 2 diabetes
M Prentki, CJ Nolan
The Journal of clinical investigation 116 (7), 1802-1812, 2006
Type 2 diabetes across generations: from pathophysiology to prevention and management
CJ Nolan, P Damm, M Prentki
The Lancet 378 (9786), 169-181, 2011
Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion
M Prentki, FM Matschinsky
Physiological reviews 67 (4), 1185-1248, 1987
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and-independent glucose-stimulated insulin secretion.
HE Hohmeier, H Mulder, G Chen, R Henkel-Rieger, M Prentki, ...
Diabetes 49 (3), 424-430, 2000
AMPK, insulin resistance, and the metabolic syndrome
NB Ruderman, D Carling, M Prentki, JM Cacicedo
The Journal of clinical investigation 123 (7), 2764-2772, 2013
Saturated fatty acids synergize with elevated glucose to cause pancreatic β-cell death
W El-Assaad, J Buteau, ML Peyot, C Nolan, R Roduit, S Hardy, E Joly, ...
Endocrinology 144 (9), 4154-4163, 2003
Are the β-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?
M Prentki, BE Corkey
Diabetes 45 (3), 273-283, 1996
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in β-cell adaptation and failure in the etiology of diabetes
M Prentki, E Joly, W El-Assaad, R Roduit
Diabetes 51 (suppl 3), S405-S413, 2002
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA …
J Buteau, R Roduit, S Susini, M Prentki
Diabetologia 42 (7), 856-864, 1999
Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion.
M Prentki, S Vischer, MC Glennon, R Regazzi, JT Deeney, BE Corkey
Journal of Biological Chemistry 267 (9), 5802-5810, 1992
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome
N Ruderman, M Prentki
Nature reviews Drug discovery 3 (4), 340-351, 2004
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
J Rung, S Cauchi, A Albrechtsen, L Shen, G Rocheleau, ...
Nature genetics 41 (10), 1110, 2009
Glucagon-like peptide 1 induces pancreatic β-cell proliferation via transactivation of the epidermal growth factor receptor
J Buteau, S Foisy, E Joly, M Prentki
Diabetes 52 (1), 124-132, 2003
Rapid mobilization of Ca 2+ from rat insulinoma microsomes by inositol-1, 4, 5-trisphosphate
M Prentki, TJ Biden, D Janjic, RF Irvine, MJ Berridge, CB Wollheim
Nature 309 (5968), 562-564, 1984
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in …
H Park, VK Kaushik, S Constant, M Prentki, E Przybytkowski, ...
Journal of Biological Chemistry 277 (36), 32571-32577, 2002
Metabolic fate of glucose in purified islet cells: glucose-regulated anaplerosis in β cells
F Schuit, A De Vos, K Moens, D Pipeleers, S Farfari, T Brun, M Prentki
Journal of Biological Chemistry 272 (30), 18572-18579, 1997
Fatty acid signaling in the β-cell and insulin secretion
CJ Nolan, MSR Madiraju, V Delghingaro-Augusto, ML Peyot, M Prentki
Diabetes 55 (Supplement 2), S16-S23, 2006
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity
J Buteau, W El-Assaad, CJ Rhodes, L Rosenberg, E Joly, M Prentki
Diabetologia 47 (5), 806-815, 2004
Metabolic signaling in fuel-induced insulin secretion
M Prentki, FM Matschinsky, SRM Madiraju
Cell metabolism 18 (2), 162-185, 2013
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