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John Goffin
John Goffin
Verified email at medportal.ca
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Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer
WD Foulkes, IM Stefansson, PO Chappuis, LR Bégin, JR Goffin, N Wong, ...
Journal of the national cancer institute 95 (19), 1482-1485, 2003
13042003
Probability of cancer in pulmonary nodules detected on first screening CT
A McWilliams, MC Tammemagi, JR Mayo, H Roberts, G Liu, K Soghrati, ...
New England journal of medicine 369 (10), 910-919, 2013
12952013
The prognostic implication of the basal-like (cyclin Ehigh/p27low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer
WD Foulkes, JS Brunet, IM Stefansson, O Straume, PO Chappuis, ...
Cancer research 64 (3), 830-835, 2004
5162004
A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment
ME Robson, PO Chappuis, J Satagopan, N Wong, J Boyd, JR Goffin, ...
Breast Cancer Research 6, 1-10, 2003
3552003
First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer: a systematic review
J Goffin, C Lacchetti, PM Ellis, YC Ung, WK Evans
Journal of Thoracic Oncology 5 (2), 260-274, 2010
2712010
Effect of combined immune checkpoint inhibition vs best supportive care alone in patients with advanced colorectal cancer: the Canadian Cancer Trials Group CO. 26 Study
EX Chen, DJ Jonker, JM Loree, HF Kennecke, SR Berry, F Couture, ...
JAMA oncology 6 (6), 831-838, 2020
2672020
Survival of patients with non-small-cell lung cancer after a diagnosis of brain metastases
A Ali, JR Goffin, A Arnold, PM Ellis
Current Oncology 20 (4), 300-306, 2013
2672013
Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study
MC Tammemagi, H Schmidt, S Martel, A McWilliams, JR Goffin, ...
The lancet oncology 18 (11), 1523-1531, 2017
2042017
The cost-effectiveness of high-risk lung cancer screening and drivers of program efficiency
S Cressman, SJ Peacock, MC Tammemägi, WK Evans, NB Leighl, ...
Journal of Thoracic Oncology 12 (8), 1210-1222, 2017
1392017
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10‐Year follow‐up data
JR Goffin, PO Chappuis, LR Bégin, N Wong, JS Brunet, N Hamel, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 2003
1342003
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers
O Straume, PO Chappuis, HB Salvesen, OJ Halvorsen, SA Haukaas, ...
Cancer Research 62 (23), 6808-6811, 2002
1332002
Cost-effectiveness of lung cancer screening in Canada
JR Goffin, WM Flanagan, AB Miller, NR Fitzgerald, S Memon, MC Wolfson, ...
JAMA oncology 1 (6), 807-813, 2015
1212015
Epidermal growth factor receptor: pathway, therapies, and pipeline
JR Goffin, K Zbuk
Clinical therapeutics 35 (9), 1282-1303, 2013
1172013
Objective responses in patients with malignant melanoma or renal cell cancer in early clinical studies do not predict regulatory approval
J Goffin, S Baral, D Tu, D Nomikos, L Seymour
Clinical cancer research 11 (16), 5928-5934, 2005
1042005
Brief report: a phase II study of sunitinib in malignant pleural mesothelioma. the NCIC Clinical Trials Group
SA Laurie, A Gupta, Q Chu, CW Lee, W Morzycki, R Feld, AH Foo, J Seely, ...
Journal of Thoracic Oncology 6 (11), 1950-1954, 2011
792011
Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment
PO Chappuis, E Donato, JR Goffin, N Wong, LR Begin, LR Kapusta, ...
Annals of oncology 16 (5), 735-742, 2005
712005
Biennial lung cancer screening in Canada with smoking cessation—outcomes and cost-effectiveness
JR Goffin, WM Flanagan, AB Miller, NR Fitzgerald, S Memon, MC Wolfson, ...
Lung Cancer 101, 98-103, 2016
662016
Lung Cancer Disease Site Group of Cancer Care Ontario’s Program in Evidence-Based Care. First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer …
J Goffin, C Lacchetti, PM Ellis, YC Ung, WK Evans
J Thorac Oncol 5 (2), 260-74, 2010
642010
CCTG CO. 26 trial: A phase II randomized study of durvalumab (D) plus tremelimumab (T) and best supportive care (BSC) versus BSC alone in patients (pts) with advanced …
EX Chen, DJ Jonker, HF Kennecke, SR Berry, F Couture, CE Ahmad, ...
Journal of Clinical Oncology 37 (4_suppl), 481-481, 2019
572019
Low prevalence of high-grade lesions detected with autofluorescence bronchoscopy in the setting of lung cancer screening in the pan-canadian lung cancer screening study
A Tremblay, N Taghizadeh, AM McWilliams, P MacEachern, DR Stather, ...
Chest 150 (5), 1015-1022, 2016
562016
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