MicroRNA expression profiles classify human cancers J Lu, G Getz, EA Miska, E Alvarez-Saavedra, J Lamb, D Peck, ... nature 435 (7043), 834-838, 2005 | 11783 | 2005 |
Discovery and preclinical validation of drug indications using compendia of public gene expression data M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ... Science translational medicine 3 (96), 96ra77-96ra77, 2011 | 852 | 2011 |
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon KM Haigis, KR Kendall, Y Wang, A Cheung, MC Haigis, JN Glickman, ... Nature genetics 40 (5), 600-608, 2008 | 692 | 2008 |
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis A Sweet-Cordero, S Mukherjee, A Subramanian, H You, JJ Roix, ... Nature genetics 37 (1), 48-55, 2005 | 490 | 2005 |
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ... Nature medicine 21 (10), 1163-1171, 2015 | 369 | 2015 |
Genome-informed targeted therapy for osteosarcoma LC Sayles, MR Breese, AL Koehne, SG Leung, AG Lee, HY Liu, ... Cancer discovery 9 (1), 46-63, 2019 | 284 | 2019 |
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer TG Oliver, KL Mercer, LC Sayles, JR Burke, D Mendus, KS Lovejoy, ... Genes & development 24 (8), 837-852, 2010 | 242 | 2010 |
Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma BE Schaffer, KS Park, G Yiu, JF Conklin, C Lin, DL Burkhart, AN Karnezis, ... Cancer research 70 (10), 3877-3883, 2010 | 237 | 2010 |
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 222 | 2020 |
Requirement for Rac1 in a K-ras–induced lung cancer in the mouse JL Kissil, MJ Walmsley, L Hanlon, KM Haigis, CF Bender Kim, ... Cancer research 67 (17), 8089-8094, 2007 | 208 | 2007 |
Oncogenic KRAS regulates amino acid homeostasis and asparagine biosynthesis via ATF4 and alters sensitivity to L-asparaginase DM Gwinn, AG Lee, M Briones-Martin-del-Campo, CS Conn, DR Simpson, ... Cancer cell 33 (1), 91-107. e6, 2018 | 192 | 2018 |
Dale's hypothesis revisited: different neuropeptides derived from a common prohormone are targeted to different processes. WS Sossin, A Sweet-Cordero, RH Scheller Proceedings of the National Academy of Sciences 87 (12), 4845-4848, 1990 | 173 | 1990 |
Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models S Vicent, R Chen, LC Sayles, C Lin, RG Walker, AK Gillespie, ... The Journal of clinical investigation 120 (11), 3940-3952, 2010 | 159 | 2010 |
A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma R Chen, P Khatri, PK Mazur, M Polin, Y Zheng, D Vaka, CD Hoang, ... Cancer research 74 (10), 2892-2902, 2014 | 157 | 2014 |
A rare population of CD24+ ITGB4+ Notchhi cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal Y Zheng, CC de la Cruz, LC Sayles, C Alleyne-Chin, D Vaka, TD Knaak, ... Cancer cell 24 (1), 59-74, 2013 | 156 | 2013 |
HIF-2α deletion promotes Kras-driven lung tumor development J Mazumdar, MM Hickey, DK Pant, AC Durham, A Sweet-Cordero, ... Proceedings of the National Academy of Sciences 107 (32), 14182-14187, 2010 | 156 | 2010 |
The genomic landscape of pediatric cancers: Implications for diagnosis and treatment EA Sweet-Cordero, JA Biegel Science 363 (6432), 1170-1175, 2019 | 155 | 2019 |
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ... Nature medicine 23 (3), 291-300, 2017 | 149 | 2017 |
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer A Vallejo, N Perurena, E Guruceaga, PK Mazur, S Martinez-Canarias, ... Nature communications 8 (1), 14294, 2017 | 139 | 2017 |
Twist1 Suppresses Senescence Programs and Thereby Accelerates and Maintains Mutant Kras-Induced Lung Tumorigenesis PT Tran, EH Shroff, TF Burns, S Thiyagarajan, ST Das, T Zabuawala, ... PLoS genetics 8 (5), e1002650, 2012 | 122 | 2012 |