Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily SE Tsutakawa, S Classen, BR Chapados, AS Arvai, LD Finger, ... Cell 145 (2), 198-211, 2011 | 320 | 2011 |
Purification and Characterization of Human NTH1, a Homolog ofEscherichia coli Endonuclease III: DIRECT IDENTIFICATION OF LYS-212 AS THE ACTIVE NUCLEOPHILIC RESIDUE S Ikeda, T Biswas, R Roy, T Izumi, I Boldogh, A Kurosky, AH Sarker, ... Journal of Biological Chemistry 273 (34), 21585-21593, 1998 | 282 | 1998 |
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome AH Sarker, SE Tsutakawa, S Kostek, C Ng, DS Shin, M Peris, E Campeau, ... Molecular cell 20 (2), 187-198, 2005 | 276 | 2005 |
Thirdhand smoke causes DNA damage in human cells B Hang, AH Sarker, C Havel, S Saha, TK Hazra, S Schick, P Jacob III, ... Mutagenesis 28 (4), 381-391, 2013 | 228 | 2013 |
Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes A Chakraborty, N Tapryal, T Venkova, N Horikoshi, RK Pandita, ... Nature communications 7 (1), 13049, 2016 | 184 | 2016 |
Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols M Takao, S Kanno, T Shiromoto, R Hasegawa, H Ide, S Ikeda, AH Sarker, ... The EMBO journal, 2002 | 172 | 2002 |
Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability SE Tsutakawa, MJ Thompson, AS Arvai, AJ Neil, SJ Shaw, SI Algasaier, ... Nature communications 8 (1), 15855, 2017 | 102 | 2017 |
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation*♦ A Chakraborty, M Wakamiya, T Venkova-Canova, RK Pandita, ... Journal of Biological Chemistry 290 (41), 24636-24648, 2015 | 100 | 2015 |
The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage JY Wang, AH Sarker, PK Cooper, MR Volkert Molecular and cellular biology 24 (13), 6084-6093, 2004 | 92 | 2004 |
Cloning and characterization of a mouse homologue (mNthl1) of Escherichia coli endonuclease III AH Sarker, S Ikeda, H Nakano, H Terato, H Ide, K Imai, K Akiyama, ... Journal of molecular biology 282 (4), 761-774, 1998 | 90 | 1998 |
Oxygen radical-induced single-strand DNA breaks and repair of the damage in a cell-free system AH Sarker, S Watanabe, S Seki, T Akiyama, S Okada Mutation Research/DNA Repair 337 (2), 85-95, 1995 | 68 | 1995 |
Tobacco toxins deposited on surfaces (third hand smoke) impair wound healing S Dhall, R Alamat, A Castro, AH Sarker, JH Mao, A Chan, B Hang, ... Clinical Science 130 (14), 1269-1284, 2016 | 66 | 2016 |
Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency S Barnhoorn, LM Uittenboogaard, D Jaarsma, WP Vermeij, M Tresini, ... PLoS genetics 10 (10), e1004686, 2014 | 66 | 2014 |
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2 S Dey, AK Maiti, ML Hegde, PM Hegde, I Boldogh, PS Sarkar, ... DNA repair 11 (6), 570-578, 2012 | 59 | 2012 |
Adverse health effects of thirdhand smoke: from cell to animal models B Hang, P Wang, Y Zhao, A Sarker, A Chenna, Y Xia, AM Snijders, ... International journal of molecular sciences 18 (5), 932, 2017 | 48 | 2017 |
NEIL2 protects against oxidative DNA damage induced by sidestream smoke in human cells AH Sarker, A Chatterjee, M Williams, S Lin, C Havel, P Jacob III, I Boldogh, ... PloS one 9 (3), e90261, 2014 | 48 | 2014 |
Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes K Imai, AH Sarker, K Akiyama, S Ikeda, M Yao, K Tsutsui, T Shohmori, ... Gene 222 (2), 287-295, 1998 | 48 | 1998 |
Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer KL Limpose, KS Trego, Z Li, SW Leung, AH Sarker, JA Shah, ... Nucleic acids research 46 (9), 4515-4532, 2018 | 46 | 2018 |
Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication M Wilamowski, M Hammel, W Leite, Q Zhang, Y Kim, KL Weiss, ... Biophysical journal 120 (15), 3152-3165, 2021 | 44 | 2021 |
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations SE Tsutakawa, AH Sarker, C Ng, AS Arvai, DS Shin, B Shih, S Jiang, ... Proceedings of the National Academy of Sciences 117 (25), 14127-14138, 2020 | 42 | 2020 |