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Genevieve Desjardins
Genevieve Desjardins
Zymeworks
Verified email at zymeworks.com
Title
Cited by
Cited by
Year
Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor
G Desjardins, CA Meeker, N Bhachech, SL Currie, M Okon, BJ Graves, ...
Proceedings of the National Academy of Sciences 111 (30), 11019-11024, 2014
472014
NMR Structure of Varkud Satellite Ribozyme Stem−Loop V in the Presence of Magnesium Ions and Localization of Metal-Binding Sites,
DO Campbell, P Bouchard, G Desjardins, P Legault
Biochemistry 45 (35), 10591-10605, 2006
462006
NMR structure of the A730 loop of the Neurospora VS ribozyme: insights into the formation of the active site
G Desjardins, E Bonneau, N Girard, J Boisbouvier, P Legault
Nucleic acids research 39 (10), 4427-4437, 2011
262011
Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme
P Bouchard, J Lacroix-Labonté, G Desjardins, P Lampron, V Lisi, ...
RNA 14 (4), 736-748, 2008
262008
Conformational dynamics and the binding of specific and nonspecific DNA by the autoinhibited transcription factor Ets-1
G Desjardins, M Okon, BJ Graves, LP McIntosh
Biochemistry 55 (29), 4105-4118, 2016
182016
An integrative NMR-SAXS approach for structural determination of large RNAs defines the substrate-free state of a trans-cleaving Neurospora Varkud Satellite …
P Dagenais, G Desjardins, P Legault
Nucleic Acids Research 49 (20), 11959-11973, 2021
102021
Anti-PD-1/LAG3 bispecific antibodies
L Fayadat-Dilman, V Juan, S Khan, S Huang, H Ying, EE Cabrera, ...
US Patent 11,072,658, 2021
52021
Increasing the therapeutic index of IL12 by engineering for tumor specific protease activation
JL Bishop, R Blackler, G Volkers, M Poffenberger, I Yu, J Smith, ...
Cancer Research 81 (13_Supplement), 1788-1788, 2021
32021
Structural characterization of DNA binding and autoinhibition by the ETS1 transcription factor
G Desjardins
University of British Columbia, 2015
22015
Anti-pd-1/lag3 bispecific antibodies
L Fayadat-Dilman, V Juan, S Khan, S Huang, H Ying, EE Cabrera, ...
US Patent App. 17/384,561, 2021
12021
Anti-pd-1/lag3 bispecific antibodies
L Fayadat-Dilman, V Juan, S Khan, S Huang, H Ying, EE Cabrera, ...
US Patent App. 17/384,539, 2021
12021
1396 TriTCE CPI: a novel trispecifc T cell engager platform with integrated PD-1/PD-L1 checkpoint inhibition engineered for the treatment of immunosuppressed tumors
MM Verstraete, M Poffenberger, M Zago, V Luu, B Ma, N Escalante, J Li, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
Masked il12 fusion proteins and methods of use thereof
R Blackler, G Volkers, D Douda, TS VON KREUDENSTEIN, G Desjardins, ...
US Patent App. 17/914,261, 2023
2023
PROTECTTM, a novel trispecific antibody masking platform with integrated immune modulation displays unique activity and differentiated modes of action
A von Rossum, G Desjardins, N Escalante, W Wong, B Harbourne, J Li, ...
Cancer Research 83 (7_Supplement), 2926-2926, 2023
2023
Masked il12 fusion proteins and methods of use thereof
G VOLKERS, TS VON KREUDENSTEIN, N AFACAN, G DESJARDINS, ...
2023
Masked il12 fusion proteins and methods of use thereof
R BLACKLER, G VOLKERS, D DOUDA, TS VON KREUDENSTEIN, ...
2021
Anti-pd-1/lag3 bispecific antibodies
L FAYADAT-DILMAN, V Juan, S Khan, S HUANG, H Ying, EE CABRERA, ...
2019
Études Structurales par Résonance Magnétique Nucléaire (RMN) du Site Actif du Ribozyme VS de Neurospora
G Desjardins-Séguin
2009
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Articles 1–18