Rajarshi Guha

Citée par

	Toutes	Depuis 2019
Citations	11151	5434
indice h	53	34
indice i10	97	73

1100

550

275

825

200620072008200920102011201220132014201520162017201820192020202120222023202464 96 169 234 282 389 451 417 562 623 648 747 913 957 1037 1099 931 784 626

Accès public

Tout afficher

65 articles

1 article

disponibles

non disponibles

Sur la base des exigences liées au financement

Coauteurs

Marc FerrerDirector, NIHAdresse e-mail validée de mail.nih.gov
Egon WillighagenTGX, NUTRIM, Maastricht University/NL, ORCID:0000-0001-7542-0286, https://social.edu.nl/@egonwAdresse e-mail validée de maastrichtuniversity.nl
Christoph SteinbeckFriedrich-Schiller-University JenaAdresse e-mail validée de uni-jena.de
James IngleseADST Laboratory, NCATS, Adjunct Investigator NHGRI, NIHAdresse e-mail validée de mail.nih.gov
Lesley MathewsNovartisAdresse e-mail validée de novartis.com
Michele CeribelliStaff Scientist, Division of Pre-Clinical Innovation, NCATS, NIHAdresse e-mail validée de nih.gov
Kelli WilsonNational Center for Advancing Translational Science (NCATS)Adresse e-mail validée de nih.gov
Noel SouthallAstraZenecaAdresse e-mail validée de astrazeneca.com
John H. Van DrieVan Drie Research LLCAdresse e-mail validée de vandrieresearch.com
Louis M. StaudtNational Cancer InstituteAdresse e-mail validée de mail.nih.gov
Ola SpjuthProfessor at Department of Pharmaceutical Biosciences, Uppsala UniversityAdresse e-mail validée de farmbio.uu.se
Andreas BenderUniversity of Cambridge; Pangea Bio; Universitatea Babeș-Bolyai; UMF ClujAdresse e-mail validée de cam.ac.uk
Stefan KuhnLecturerAdresse e-mail validée de ut.ee
Ajit JadhavPfizerAdresse e-mail validée de pfizer.com
Eugen BuehlerAstraZenecaAdresse e-mail validée de astrazeneca.com
YIBIN YANGFox Chase Cancer CenterAdresse e-mail validée de fccc.edu
Marlon PierceIndiana UniversityAdresse e-mail validée de iu.edu
Geoffrey FoxProfessor of Computer Science, University of Virginia, Biocomplexity InstituteAdresse e-mail validée de virginia.edu
Geoffrey HutchisonProfessor of Chemistry, University of PittsburghAdresse e-mail validée de pitt.edu
Nina JeliazkovaIdeaconsult Ltd.Adresse e-mail validée de ideaconsult.net

Suivre

Rajarshi Guha

Vertex Pharmaceuticals

Adresse e-mail validée de vrtx.com - Page d'accueil

Chemistry Cheminformatics Bioinformatics Machine Learning Visualization


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma Y Yang, AL Shaffer, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ... Cancer cell 21 (6), 723-737, 2012	607	2012
Recent developments of the chemistry development kit (CDK)-an open-source java library for chemo-and bioinformatics C Steinbeck, C Hoppe, S Kuhn, M Floris, R Guha, EL Willighagen Current pharmaceutical design 12 (17), 2111-2120, 2006	571	2006
The Blue Obelisk—interoperability in chemical informatics R Guha, MT Howard, GR Hutchison, P Murray-Rust, H Rzepa, ... Journal of chemical information and modeling 46 (3), 991-998, 2006	493	2006
The Chemistry Development Kit (CDK) v2. 0: atom typing, depiction, molecular formulas, and substructure searching EL Willighagen, JW Mayfield, J Alvarsson, A Berg, L Carlsson, ... Journal of cheminformatics 9, 1-19, 2017	467	2017
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ... Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014	422	2014
Unexplored therapeutic opportunities in the human genome TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ... Nature reviews Drug discovery 17 (5), 317-332, 2018	393	2018
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy SA Hasson, LA Kane, K Yamano, CH Huang, DA Sliter, E Buehler, ... Nature 504 (7479), 291-295, 2013	390	2013
Structure− activity landscape index: identifying and quantifying activity cliffs R Guha, JH Van Drie Journal of chemical information and modeling 48 (3), 646-658, 2008	361	2008
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS Pathog 12 (7), e1005763, 2016	307	2016
Chemical informatics functionality in R R Guha Journal of Statistical Software 18, 1-16, 2007	291	2007
RNA polymerase II regulates topoisomerase 1 activity to favor efficient transcription L Baranello, D Wojtowicz, K Cui, BN Devaiah, HJ Chung, KY Chan-Salis, ... Cell 165 (2), 357-371, 2016	282	2016
PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ... Cancer Discovery 7 (8), 884-899, 2017	280	2017
What are we ‘tweeting’about obesity? Mapping tweets with topic modeling and Geographic Information System D Ghosh, R Guha Cartography and geographic information science 40 (2), 90-102, 2013	272	2013
Pharos: collating protein information to shed light on the druggable genome DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ... Nucleic acids research 45 (D1), D995-D1002, 2017	269	2017
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors M Ceribelli, PN Kelly, AL Shaffer, GW Wright, W Xiao, Y Yang, ... Proceedings of the National Academy of Sciences 111 (31), 11365-11370, 2014	227	2014
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ... Cancer cell 24 (1), 90-104, 2013	217	2013
Modelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectives KC Bulusu, R Guha, DJ Mason, RPI Lewis, E Muratov, YK Motamedi, ... Drug discovery today 21 (2), 225-238, 2016	206	2016
ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses R Jossé, SE Martin, R Guha, P Ormanoglu, TD Pfister, PM Reaper, ... Cancer research 74 (23), 6968-6979, 2014	189	2014
Navigating structure–activity landscapes J Bajorath, L Peltason, M Wawer, R Guha, MS Lajiness, JH Van Drie Drug Discovery Today 14 (13-14), 698-705, 2009	188	2009
On exploring structure–activity relationships R Guha In silico models for drug discovery, 81-94, 2013	184	2013

Le système ne peut pas réaliser cette opération maintenant. Veuillez réessayer plus tard.

Articles 1–20

Nombre de citations par an

Citations en double

Citations fusionnées

Ajouter les coauteursCoauteurs

Suivre

Citée par

Coauteurs