3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing K Takayama, K Kawabata, Y Nagamoto, K Kishimoto, K Tashiro, ... Biomaterials 34 (7), 1781-1789, 2013 | 312 | 2013 |
Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction K Takayama, M Inamura, K Kawabata, K Katayama, M Higuchi, K Tashiro, ... Molecular Therapy 20 (1), 127-137, 2012 | 286 | 2012 |
In vitro and animal models for SARS-CoV-2 research K Takayama Trends in pharmacological sciences 41 (8), 513-517, 2020 | 210 | 2020 |
Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes K Takayama, Y Morisaki, S Kuno, Y Nagamoto, K Harada, N Furukawa, ... Proceedings of the National Academy of Sciences 111 (47), 16772-16777, 2014 | 208 | 2014 |
Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction K Takayama, M Inamura, K Kawabata, M Sugawara, K Kikuchi, M Higuchi, ... Journal of hepatology 57 (3), 628-636, 2012 | 190 | 2012 |
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants T Tamura, J Ito, K Uriu, J Zahradnik, I Kida, Y Anraku, H Nasser, M Shofa, ... Nature communications 14 (1), 2800, 2023 | 160 | 2023 |
The structural basis of accelerated host cell entry by SARS‐CoV‐2 M Seyran, K Takayama, VN Uversky, K Lundstrom, G Palù, SP Sherchan, ... The FEBS journal 288 (17), 5010-5020, 2021 | 155 | 2021 |
Carbon-based nanomaterials: promising antiviral agents to combat COVID-19 in the microbial-resistant era Á Serrano-Aroca, K Takayama, A Tuñón-Molina, M Seyran, SS Hassan, ... ACS nano 15 (5), 8069-8086, 2021 | 152 | 2021 |
Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure Y Nagamoto, K Takayama, K Ohashi, R Okamoto, F Sakurai, M Tachibana, ... Journal of hepatology 64 (5), 1068-1075, 2016 | 152 | 2016 |
Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX M Inamura, K Kawabata, K Takayama, K Tashiro, F Sakurai, K Katayama, ... Molecular Therapy 19 (2), 400-407, 2011 | 143 | 2011 |
The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using type I collagen and Swiss 3T3 cell sheets Y Nagamoto, K Tashiro, K Takayama, K Ohashi, K Kawabata, F Sakurai, ... Biomaterials 33 (18), 4526-4534, 2012 | 131 | 2012 |
Virological characteristics of the SARS-CoV-2 Omicron BA. 2.75 variant A Saito, T Tamura, J Zahradnik, S Deguchi, K Tabata, Y Anraku, I Kimura, ... Cell host & microbe 30 (11), 1540-1555. e15, 2022 | 104 | 2022 |
Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system K Takayama, K Igai, Y Hagihara, R Hashimoto, M Hanawa, T Sakuma, ... Nucleic Acids Research 45 (9), 5198-5207, 2017 | 93 | 2017 |
Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes K Takayama, Y Nagamoto, N Mimura, K Tashiro, F Sakurai, M Tachibana, ... Stem cell reports 1 (4), 322-335, 2013 | 91 | 2013 |
Protective face masks: current status and future trends A Tuñón-Molina, K Takayama, EM Redwan, VN Uversky, J Andrés, ... ACS Applied Materials & Interfaces 13 (48), 56725-56751, 2021 | 86 | 2021 |
Generation of human bronchial organoids for SARS-CoV-2 research T Suzuki, Y Itoh, Y Sakai, A Saito, D Okuzaki, D Motooka, S Minami, ... biorxiv, 2020.05. 25.115600, 2020 | 80 | 2020 |
Generation of safe and therapeutically effective human induced pluripotent stem cell‐derived hepatocyte‐like cells for regenerative medicine K Takayama, N Akita, N Mimura, R Akahira, Y Taniguchi, M Ikeda, ... Hepatology Communications 1 (10), 1058-1069, 2017 | 76 | 2017 |
Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection T Yoshida, K Takayama, M Kondoh, F Sakurai, H Tani, N Sakamoto, ... Biochemical and biophysical research communications 416 (1-2), 119-124, 2011 | 76 | 2011 |
Efficient and directive generation of two distinct endoderm lineages from human ESCs and iPSCs by differentiation stage-specific SOX17 transduction K Takayama, M Inamura, K Kawabata, K Tashiro, K Katayama, F Sakurai, ... PloS one 6 (7), e21780, 2011 | 72 | 2011 |
Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine T Ozawa, K Takayama, R Okamoto, R Negoro, F Sakurai, M Tachibana, ... Scientific reports 5 (1), 16479, 2015 | 70 | 2015 |